A nano-sulfur containing composition and application thereof

a technology of nano-sulfur and composition, applied in the field of nano-sulfur containing composition and application, can solve the problems of large specific application limitations, poor practical clinical application effect, and almost obsolete in the mark

Inactive Publication Date: 2020-05-21
SUZHOU CANASTAR NEW MATERIALS TECH CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although sulfur is widely used, its specific application is greatly limited.
For example, commercially available sulfur preparations such as sulfur ointments or sulfur creams, although indicated in their instructions that it can treat many skin diseases, the effects are not good in practical clinical applications, and are almost obsolete in the market.
The main reasons are as follows: 1) Sulfur is insoluble in water, so the sulfur particles in the paste are large (usually several tens of micrometers) and are difficult to be absorbed by the skin, low in antibacterial activity and bioavailability, and not good in medical effect; 2) The sulfur ointment or cream, with more amount of sulfur used, is irritating.
However, the description of the nano-sulfur in this patent is limited to the nanometer sulfur particle size of 50 nm and it can be obtained by processing elemental sulfur using nanotechnology (see paragraphs and of the specification), ie the patent does not specifically describe how to obtain nano-sulfur powder with a particle size of about 50 nm and the characterization data of the nano-sulfur powder.
According to the existing documentary records (for example, CN1453205A and CN104944381), preparation processes of nano-sulfur powder are usually very complicated, resulting in high cost; in addition, although the particle size of the nano-sulfur powder as a raw material is relatively small, once added into the acne toner system or other application system, the nano-sulfur powder will be significantly agglomerated, forming a larger particle size of sulfur particles, so that it is difficult to effectively act on bacterium or germs on the surface of or in the pores of the skin.
Similarly, it is difficult to effectively sterilize other substrates with bacteria or bacteria.
The sulfur containing product obtained by such method, its sulfur is easy to agglomerate, and has low activity, poor effect and limited application.

Method used

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  • A nano-sulfur containing composition and application thereof

Examples

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example 1

[0110]This example provides a nano-sulfur containing composition, the raw materials of which comprise sodium thiosulfate pentahydrate, hydroxypropyl starch ether, hydrochloric acid and water. The preparation method was as follows:

[0111]50 g of sodium thiosulfate pentahydrate and 1 g of hydroxypropyl starch ether were weighted, and sodium thiosulfate pentahydrate was dissolved in water to prepare an aqueous sodium thiosulfate solution containing 50% by mass of sodium thiosulfate. Hydroxypropyl starch ether was then added to the aqueous sodium thiosulfate solution, and finally a 10% by mass hydrochloric acid solution was added to the aqueous sodium thiosulfate solution (wherein the molar ratio of the added thiosulfate to the hydrogen ion was 1:2), and the system was ultrasonically stirred until the reaction was completed, to give a nano-sulfur containing composition. The mass content of nano-sulfur in the obtained nano-sulfur containing composition was about 3.06%. The nano-sulfur con...

example 2

[0112]This example provides a nano-sulfur containing composition, the raw materials of which comprise sodium thiosulfate, guar gum, acetic acid, and water. The preparation method was as follows:

[0113]50 g of sodium thiosulfate and 1.5 g of guar gum were weighed, and sodium thiosulfate was dissolved in water to prepare an aqueous sodium thiosulfate solution containing 60% by mass of sodium thiosulfate, and then guar gum was added to the aqueous sodium thiosulfate solution, and finally a 10% by mass acetic acid solution was added to the sodium thiosulfate solution (wherein, the molar ratio of added thiosulfate to hydrogen ion was 1.05:2), and the system was ultrasonically stirred until the reaction was completed, to give a nano-sulfur containing composition. The mass content of nano-sulfur in the obtained nano-sulfur containing composition was about 2.17%. The nano-sulfur containing composition prepared in this example further contained sodium acetate as a by-product, which can be use...

example 3

[0114]This example provides a nano-containing sulfur composition, the raw materials of which comprise sodium thiosulfate, phosphorylated distarch phosphate, acetic acid and water. The preparation method was as follows:

[0115]50 g of sodium thiosulfate and 2 g of phosphorylated di starch phosphate were weighted, and sodium thiosulfate was dissolved in water to prepare an aqueous sodium thiosulfate solution containing 65% by mass of sodium thiosulfate; the phosphorylated disstarch phosphate was added to a 40% by mass acetic acid solution to form a mixed solution, and then the mixed solution was added to the aqueous sodium thiosulfate solution (wherein the molar ratio of the added thiosulfate to the hydrogen ion was 1:2), and the system was ultrasonically stirred until the reaction was completed, to give a nano-sulfur containing composition. The mass content of nano-sulfur in the obtained nano-sulfur containing composition was about 5.9%. The nano-sulfur containing composition prepared ...

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Abstract

A composition containing nano-sulfur and an application thereof, the composition containing nano-sulfur contains nano-sulfur and further contains an anti-agglomeration agent used for preventing or delaying the agglomeration of the nano-sulfur, is provided. The composition containing nano-sulfur may be widely used for preparing toiletries for use on the surface of the skin on humans or animals, pharmaceutical compositions treating skin disorders, pesticides, preservatives for vegetables and fruits, additives for animal feed, additives for mold prevention in paint, mold prevention agents for textiles or (textile) mite-killing agents. The composition containing nano-sulfur is easy to prepare, and the nano-sulfur may remain in the nano state for a long time, reducing or even eliminating the occurrence of the agglomeration of the nano-sulfur, while achieving the goals of being applied in various products and preventing fungus by simply adding a very small amount.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application claims priority to PCT Application No. PCT / CN2018 / 099661, having a filing date of Aug. 9, 2018, which is based on Chinese Application No. 201710679091.X, having a filing date of Aug. 10, 2017, the entire contents both of which are hereby incorporated by reference.FIELD OF TECHNOLOGY[0002]The following relates to a nano-sulfur containing composition and application thereof.BACKGROUND[0003]Sulfur is a very active non-metallic element that is widely used in the manufacture of sulfuric acid, agricultural chemicals, chemical fibers, rubber, dyes, paper-making, pharmaceuticals, explosives, matches, etc. Sulfur plays an important role in our daily lives, such as sulfuric acid for disinfection, sulfur ointment for treating skin diseases, etc. Sulfur in nature is also closely related to our health. For example, sulfur hot spring is called “ soup for skin”, which has the effect of softening the stratum corneum of skin and efficacy ...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): C01B17/02
CPCC01P2004/64C01B17/0248A61K47/36A01N59/02A23B7/157A23K20/20A61K8/23A61K8/73A61K8/732A61K8/733A61K8/736A61K8/737A61K33/04A23V2002/00A61Q17/005A61K45/06A61K33/06A61K33/30A61K33/22A61P31/10A61P35/00A61P17/00A01N59/14A23K20/163A23K20/105A61K2800/413A61K2800/412A61K2300/00A23V2250/1624A23V2250/1614A23V2250/5026A23V2200/10C01B17/06C01B17/10
Inventor XIA, KUI
Owner SUZHOU CANASTAR NEW MATERIALS TECH CORP
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