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3 results about "Human endometrium" patented technology
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Osmium complex, its preparation method and application in preparation of medicine for treating endometriosis
The application discloses an osmium complex, a preparation method thereof and application of the osmium complex in preparation of a medicine for treating endometriosis. The complex has a near-infrared light catalytic treatment effect on human endometrial ectopic cells (12Z), can generate superoxide anions and singlet oxygen under irradiation of a 700 nm light source, and has catalytic oxidation ability on NADH / NADPH in the 12Z cells. The series of complexes have good proliferation inhibition ability (IC 50 <40 μM) on the 12Z cells, and the proliferation inhibition ability on the 12Z cells is enhanced with optimization of a ligand structure, which has important significance for research on a new medicine for treating endometriosis and provides a new idea for developing a photodynamic treatment medicine for endometriosis in a clinic.
Owner:SUN YAT SEN UNIV
Medicinal preparation for repairing endometrial injury
The invention provides a pharmaceutical preparation for repairing endometrial injury, and belongs to the technical field of biomedicine. The pharmaceutical preparation takes improved polypeptide as an active ingredient, and the amino acid sequence of the improved polypeptide is shown as SEQ ID NO.5. Experimental results show that the polypeptide can significantly promote proliferation and migration of human endometrial stromal cells, still maintains low cytotoxicity under high concentration, and shows excellent safety. Furthermore, in a rat endometrial mechanical injury model, the preparation can obviously increase the endometrial thickness, improve the Ki-67 positive cell rate, enhance the proliferation activity of endometrial cells and promote the repair of damaged tissues. Compared with the original polypeptide, the preparation disclosed by the invention shows unexpected technical effects in the aspects of repairing activity and safety, and has a good application prospect.
Owner:BEYOND REGENERATIVE MEDICINE (HANGZHOU) CO LTD
A method for the production of a human embryonic stem cell line + Methods for controlled construction and advanced differentiation of human endometrial organoids from human endometrial epithelial stem cells
PendingCN122146570AVertebrate cellsArtificial cell constructsHuman embryonic stem cell lineEndometrial Disorder
Owner:梅州市人民医院