A CD-ROM staggered optical storage system includes CD-ROM drive walls, a CD storage rack, a CD-ROM manipulator assembly, a distribution box, etc. The CD-ROM drive walls are composed of two rows of CD-ROM drive arranged in opposite staggered arrangement, the CD storage rack is used for storing that CD case, a stack of optical disc is stored in each optical disc case. The CD-ROM manipulator assemblyincludes a CD-ROM cassette push-pull manipulator, a CD access manipulator and a guide rail support, and the whole system running process comprises the optical disc manipulator assembly is moved alonga track in a channel between two rows of optical disc storage frames to a designated optical disc cartridge position, the push-pull manipulator of the optical disc case pulls out the optical disc case, the optical disc access manipulator takes out the optical disc and puts it into the optical disc drive in turn, after reading and writing, the optical disc access manipulator takes out the opticaldisc and puts it back into the optical disc case, and the push-pull manipulator pushes the optical disc case back to the original position.