22results about "Bis-indole indigos" patented technology

The present invention relates to methods for making compounds of formula (I) including violacein, violacein analogues and derivatives thereof, and to compositions, cells, and fermentation liquids comprising the compounds resulting from these methods.

Method of making an aqueous aniline-free or aniline-free and N-methylaniline-free leucoindigo solution from an aqueous leucoindigo solution comprising aniline or aniline and N-methylaniline, the concentration of aniline or aniline and N-methylaniline being determined according to ISO 14362-1:2017(E), wherein said leucoindigo is in the form of an alkali metal salt, the method comprising at least steps (A) to (C): (A) providing a liquid stream comprising said aqueous leucoindigo solution comprising said amine(s); (B) providing a purification stream; (C) bringing into contact said liquid stream with said purification stream.

Use of an encapsulated natural color for coloring a household, industrial or institutional (HI&I) product wherein the encapsulated natural color is stable in water to simulated solar irradiation at 765 Watt in accordance with International Commission on Illumination 85 (1989, Table 4, 3 mm window glass) reference sun for a period of between 8 hours and 16 hours.

The present invention relates to methods for making compounds of formula (I) including violacein, violacein analogues and derivatives thereof, and to compositions, cells, and fermentation liquids comprising the compounds resulting from these methods.

The present invention discloses a reducing dye dispersant, its application and a preparation method of a reducing dye. The reducing dye dispersant is an aqueous solution of a copolymer and an alkali. The copolymer is one or more of an ethylene-maleic anhydride alternating copolymer, a propylene-maleic anhydride alternating copolymer, and an isobutylene-maleic anhydride alternating copolymer. Different from a graft copolymer, this copolymer is an alternating copolymer, and the ethylene, propylene, and isobutylene groups and the maleic anhydride groups in its structural units alternate. Since the basic unit of the olefin-maleic anhydride alternating copolymer is a hydrophobic olefin unit and a hydrophilic maleic group after being dissolved by an alkali, the molecule has amphiphilicity. Different from a small molecule dispersant, this dispersant can form a self-assembled structure in the reducing dye dispersion liquid, better wrap the reducing dye colloidal particles, and thus exhibit better dispersion performance. This dispersant only contains three elements of carbon, hydrogen, and oxygen, does not contain elements such as N and S, and has high environmental friendliness.

The present invention provides a composition comprising indigo carmine and a copper (II) metal ion or a salt or hydrate thereof, wherein the composition has a CD value of ≤1.5 and a pH≤5. The present invention significantly increases the shelf-life of aqueous indigo carmine formulations at pH≤5 without requiring special filling or storage conditions to physically remove oxygen from the system. In doing so, aqueous solutions comprising indigo carmine dye are stabilized and suitable for use in, for example, colorized disinfection systems.

The present invention relates to the field of fine chemical technology, and in particular to a method for hydrogenating indigo to form indigo white; the method comprising, in an alkaline environment, hydrogenating and reducing indigo to form hydrogenated indigo; wherein, a single-atom platinum-carbon catalyst is used, in which platinum metal is loaded on a carbon support in the form of a single atom or a cluster; and the platinum content in the platinum-carbon catalyst is 0.2-10wt%. The present invention adopts a catalytic hydrogenation reduction method to reduce indigo to hydrogenated indigo, which can ensure the continuous production of indigo leuco-body, has high efficiency, short reduction time, no wastewater during the production process, and effectively reduces environmental pollution; relative to the use of a sulfur-containing reducing agent, it has greater production flexibility, effectively reduces the amount of wastewater in the dyeing process, reduces the cost of wastewater treatment, saves resources, and protects the environment.

The present invention relates to a method for separating and purifying indigo from a microbial fermentation broth, which comprises the following steps: Step 1, pretreatment of the microbial cells: separating the solid and liquid of the fermentation broth of indigo-producing microorganisms to obtain microbial cells; Step 2, cell disruption: disrupting the microbial cells obtained in Step 1 by mechanical disruption, chemical disruption or a combination of mechanical and chemical disruption to allow the content to flow out, obtaining a disrupted sample; Step 3, washing and centrifugation: adding a washing solvent to the disrupted sample obtained in Step 2, washing the disrupted sample several times, centrifuging, pouring off the upper liquid, collecting and combining the bottom solids to obtain solids; Step 4, drying: drying the solids obtained in Step 3 to obtain an indigo product. The process flow of the present invention is simple, the obtained indigo has a high color value, good purity and high yield, and the equipment used in the separation and purification process are all mature industrialized equipment with large capacity, realizing the industrialization of the separation and purification of indigo from microbial fermentation broth.

The present invention relates to the synthesis of dyes. More specifically, the present invention is a method for preparing substituted or unsubstituted indigo, which comprises reacting a substituted or unsubstituted anthranilic acid with glyoxylic acid in a solvent in the presence of a metal catalyst under hydrogenation to obtain a substituted or unsubstituted 2-(carboxymethylamino)benzoic acid, and a step of converting the substituted or unsubstituted 2-(carboxymethylamino)benzoic acid into a substituted or unsubstituted indigo.

The invention discloses a preparation method of indigo carmine, which comprises the following steps: (1) adding indigo into chloralkane, stirring and controlling the temperature, and dropwise adding chlorosulfonic acid for sulfonation reaction; after the reaction is finished, controlling the temperature, adding deionized water, stirring, standing for layering, removing a lower-layer organic phase, adding liquid caustic soda into an upper-layer water phase under the temperature control, separating out a slurry solid until the pH value of a mixture of the slurry solid and the solution is greater than or equal to 13, cooling to be less than or equal to 10 DEG C, and filtering; washing the filter cake with cold deionized water and methanol in sequence to obtain an indigo carmine wet crude product; (2) adding the crude product obtained in the step (1) into deionized water, heating to 90 DEG C or above, completely dissolving the crude product, adding activated carbon, stirring, filtering while hot, carrying out reduced pressure distillation on filtrate, cooling to 10 DEG C or below, and filtering; and washing the filter cake with cold deionized water and acetone in sequence, and carrying out vacuum drying to obtain an indigo carmine product. The method has the advantages of simplicity in operation, high product yield, low cost and small amount of wastewater and waste solvent.

To provide a compound which has a high transmittance in a specific region of near-infrared (900 nm-1200 nm), excellent ability of cutting near-infrared of 700 nm-800 nm, and good heat resistance.SOLUTION: The invention provides a complex salt obtained by reacting a compound represented by the formula in the figure with a metal salt in a solvent. (In the formula, X41 to X48 are each independently H, an alkyl group, or the like.)SELECTED DRAWING: Figure 1

A biosynthetic method and composition for producing an Indigo dyestuff including Indigotin and Indirubin. Tryptophanase (TRP) and flavin-containing monooxygenase (FMO) are generated from a genetically-modified organism having a vector coding for tryptophanase and flavin-containing monooxygenase. The conversion of L-tryptophan to Indigo dyestuff is converted by the generated TRP and FMO in the presence of one or more bioactive additives selected from the cysteine, 2-oxindole, or 2-indoxyl to form a dyestuff having a ratio of Indigotin to Indirubin by weight between 1:0.1 to 1:4. The dyestuff has a color hue defined by CIE XYZ color space with X: 0.1920 to 0.2481, Y: 0.2537 to 0.2019, Z: 0.5543 to 0.5501. Selectable and reproduceable color hues are provided.

The present disclosure relates to an indoline derivative that inhibits CXXC5-Dvl interaction, a preparation method thereof and a use thereof. The present disclosure has resolved the low solubility of a conventional indoline derivative and efficiently activates the Wnt / β-catenin signaling pathway through excellent activity by which CXXC5-Dvl interaction is inhibited, and thus can be effectively used for the effects of treating, alleviating or preventing diseases associated with CXXC5-Dvl interaction activity.

The application discloses a hair dyeing molecule for improving hair dyeing color fastness and hair oxidation resistance performance and a synthesis method thereof. The hair dyeing molecule is prepared by esterification or amidation reaction of a natural pigment molecule with a phenolic hydroxyl group, an alcoholic hydroxyl group, an amino group or an imino group structure and an organic acid containing an alpha, beta-carbon-carbon double bond, so as to obtain a natural pigment molecule derivative with an alpha-carbonyl carbon-carbon double bond structure. The improved pigment molecule is connected to the keratin of the hair through a chemical bond by a thiol click reaction, so that the pigment residence performance is greatly improved, and the color fastness effect is improved.

An aqueous leucoindigo solution comprising an aromatic amine in the form of aniline or aniline and N-methylaniline, wherein the leucoindigo is in the form of an alkali metal salt; wherein the concentration of the aromatic amine is below 40 ppm as determined according to ISO 14362-1 :2017(E); and wherein the concentration of the leucoindigo salt is in the concentration range of 5 to 45 wt.-% based on the total weight of the solution and wherein the solution is stable at a temperature of 23 °C; or wherein the concentration of the leucoindigo salt is in the concentration range of 45 to 65 wt.-% based on the total weight of the solution and wherein the solution is stable at a temperature of 60 °C.

A biosynthetic method and composition for producing indigo dyes comprising indigotin and isatin. A tryptophanase (TRP) and a flavin monooxygenase (FMO) can be produced through a transgenic organism having carrier encoded tryptophanase and flavin monooxygenase. The produced tryptophanase and flavin monooxygenase convert L-tryptophan into indigo dyes in the presence of one or more bioactive additives selected from cysteine, 2-hydroxyindole, or 2-indoxyl, and the weight ratio of indigotin to isatin in the dyes is between 1:0.1 to 1:4. The dyes have a hue of X: 0.1920 to 0.2481, Y: 0.2537 to 0.2019, Z: 0.5543 to 0.5501 in the CIE XYZ color space definition. Selectable and repeatable dyeing hues are provided.

The present invention relates to processes for the preparation of compounds of formula (I) comprising violacein, violacein analogs and derivatives thereof, and to compositions, cells and fermentation liquids comprising the compounds obtained by these processes.

The present invention relates to a series of novel indigo-type structures, alizarin-type structures and anthraquinone-type structures comprising various substituents, and methods for their synthesis. In one aspect the invention provides a dye comprising one of novel structures. Embodiments of the present invention stem from the realization that it is possible to add pendant or functional groups to certain natural compounds, particularly indigo, alizarin and anthraquinone based compounds to improve their textile dyeing properties to be competitive with fossil fuel based dyes.

The invention provides a novel solid-liquid alkali fusion synthesis kettle which comprises a kettle body, a motor, a stirring shaft and stirring blades, and further comprises at least one guide cutting plate and a plurality of tangential baffles, the tangential baffles are obliquely arranged on the inner wall of the kettle body at intervals; the guide cutting plate is fixed on the stirring shaft and faces the inner wall of the kettle body, and a local reaction area is formed between the guide cutting plate and the tangential baffle when the guide cutting plate rotates along with the stirring shaft. The reaction kettle has an efficient local reaction area, materials are continuously centrifugally thrown out, cut and mixed, the limitation of traditional frame type stirring is broken through, the contact area of solid-phase, liquid-phase and gas-phase materials is increased, and the reaction speed and the mixing uniformity are improved; the method is suitable for exothermic reaction between bulky solids such as sylvite and gas, has obvious advantages in indigo blue production, can be popularized to other similar solid-liquid-gas multiphase reaction processes, and has wide application prospects.

The present invention provides a composition containing a compound represented by formula (1), a curable compound, and a solvent. Also provided are a film, an optical filter, a solid-state imaging element, an image display device, an infrared sensor, and a camera module using the composition.

A biosynthetic method and composition for producing an Indigo dyestuff including Indigotin and Indirubin. Tryptophanase (TRP) and flavin-containing monooxygenase (FMO) are generated from a genetically-modified organism having a vector coding for tryptophanase and flavin-containing monooxygenase. The conversion of L-tryptophan to Indigo dyestuff is converted by the generated TRP and FMO in the presence of one or more bioactive additives selected from the cysteine, 2-oxindole, or 2-indoxyl to form a dyestuff having a ratio of Indigotin to Indirubin by weight between 1:0.1 to 1:4. The dyestuff has a color hue defined by CIE XYZ color space with X: 0.1920 to 0.2481, Y: 0.2537 to 0.2019, Z: 0.5543 to 0.5501. Selectable and reproduceable color hues are provided.

Method of making an aqueous aniline-free or aniline-free and N-methylaniline-free leucoindigo solution from an aqueous leucoindigo solution comprising aniline or aniline and N-methylaniline, the concentration of aniline or aniline and N-methylaniline being determined according to ISO 14362-1:2017(E), wherein said leucoindigo is in the form of an alkali metal salt, the method comprising at least steps (A) to (C): (A) providing a liquid stream comprising said aqueous leucoindigo solution comprising said amine(s); (B) providing a purification stream; (C) bringing into contact said liquid stream with said purification stream.