41results about How to "Avoid disability" patented technology

The present invention overcomes limitations of the prior art by providing new compounds and methods for the treatment of conditions, such as neurodegenerative diseases (e.g., multiple sclerosis), psychiatric disorders (e.g., psychosis, bipolar disorder, depression, neuropathic pain), conditions involving CNS-mediated chronic pain, spinal cord injuries, and other diseases or injuries.

Disclosed herein are novel oleanolic acid derivatives. Methods of preparing these compounds are also disclosed. The oleanolic acid derivatives of this invention may be used for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.

This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula:

wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.

This invention provides novel compounds comprising the following anti-inflammatory pharmacore:

wherein X, R₁ and R₂ are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.

The present invention features monocyclic cyanoenone compositions and methods for using the same in the treatment of diseases such as cancer, inflammatory diseases and neurodegenerative diseases.

A taping tape includes: a base material 12 having elasticity; an adhesive layer attached to one side of the base material 12; and plural slits 14 that are formed along one direction on an inner side of the base material 12 and are arranged parallel to each other. Both side edge portions 12a and 12b of the base material 12 in the vicinities of end portions of the slits 14 are formed obliquely to each other towards a longitudinal direction center of the base material 12 from the vicinities of the end portions of the slits 14 to base material end portions 12c and 12d positioned on extensions of the slits 14. The end portions of the slits 14 curve towards the center of the base material 12 along the side edge portions 12a and 12b.

A transparent substrate with a multilayer anti-glare coating includes a transparent substrate; a first coating layer formed on the transparent substrate and being formed of a first dielectric layer having a refractive index of n1; a second coating layer formed on the first coating layer and being formed of a metal oxide layer having a refractive index of n2; a third coating layer formed on the second coating layer and being formed of a second dielectric layer having a refractive index of n3; and a fourth coating layer formed on the third coating layer and being formed of a third dielectric layer having a refractive index of n4. The refractive indexes of the coating layers satisfy: n1=n3>n2>n4.

Compositions and methods of using SerpinF2-binding molecules for preventing and/or reducing organ damage, functional disability or mortality in a patient at risk due to the activity of SerpinF2 and/or plasminogen activators on tissue injury. Also provided are compositions and methods of using SerpinF2-binding molecules for inhibiting hemorrhage, edema, and apoptosis. Methods for the preparation of medicaments for such methods of treatment and prevention are provided.

The invention discloses one group of primers for detecting FVIII/FIX gene mutations of a patient with hemophilia and application of one group of primers. The primers are 8 pairs of F9 primers, 39 pairs of 22 inversion 3 F8 primers and 1 inversion 4 F8 primers, can be used for etiological classification of hemophilia, can be applied to treatment of a non-factor drug to the hemophilia according to etiological classification of the hemophilia and can enable the patient with the hemophilia to change from severe type to a moderate type and a mild type. By adopting the primers, an acquired getter FVIII/FIX:C can be returned mormality; and further verified that the hemophilia etiological classification method provided by the invention is definite and reliable, opens up a new thought and a new wayof preventing hemophilia bleeding and avoiding disability and has an important significance of guiding prenatal and postnatal care and blocking inheritance.

The invention relates to the technical field of meat duck cage culture, in particular to a safe and efficient duck catching method in a duck shed. According to the safe and efficient duck catching method for the duck shed, duck catching operation is realized through nondestructive cage door opening hooks, a duck-catching slow-down platform mechanism, a duck catching trolley for movement and a duckpushing plate, so that the duck catching time is greatly shortened; and meat ducks in duck cages on the left and right sides simultaneously slide down along a sliding plate of the duck-catching slow-down platform mechanism at the middle of the duck shed, and the time from opening the cage door to completing duck catching and closing the cage door is about 30-40s, so that the duck catching processis greatly shortened, and manpower and material resources are saved.

The invention belongs to the field of ankle rehabilitation training, and especially discloses ankle rehabilitation training apparatus for patients with gout. In order to solve the problem of unable meeting of needs of use caused by necessity of frequent manual rehabilitation training by accompanying personnel at present, the invention discloses a scheme as follows: the ankle rehabilitation training apparatus for the patients with gout comprises an apparatus body which adopts a hollow structure; a fixing groove is formed at a bottom end of an inner wall of the apparatus body; an iron block is provided inside the fixing groove in a movable way; a mounting base is connected with a top end of the iron block, and extends outside the fixing groove; the iron block is provided with a spring on oneside far away from the mounting base; one end of the spring, which is far away from the iron block, is arranged on an inner-wall bottom end of the fixing groove; a magnet is provided on one side of an inner wall of the fixing groove; and a movable plate is provided on the iron block on one side far away from the magnet. The ankle rehabilitation training apparatus for the patients with gout is rational in structure, and capable of realizing rehabilitation training of bare feet from multiple angles; and moreover, the ankle rehabilitation training apparatus is also capable of avoiding disabilityof the patients caused by non-flowing of the blood, thereby meeting the needs of use.