43results about How to "Avoid disability" patented technology

The present invention overcomes limitations of the prior art by providing new compounds and methods for the treatment of conditions, such as neurodegenerative diseases (e.g., multiple sclerosis), psychiatric disorders (e.g., psychosis, bipolar disorder, depression, neuropathic pain), conditions involving CNS-mediated chronic pain, spinal cord injuries, and other diseases or injuries.

This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula:wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.

Disclosed herein are novel oleanolic acid derivatives. Methods of preparing these compounds are also disclosed. The oleanolic acid derivatives of this invention may be used for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.

This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula:wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.

This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula:wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.

This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula:wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.

Disclosed herein are novel oleanolic acid derivatives. Methods of preparing these compounds are also disclosed. The oleanolic acid derivatives of this invention may be used for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.

The present invention features monocyclic cyanoenone compositions and methods for using the same in the treatment of diseases such as cancer, inflammatory diseases and neurodegenerative diseases.

The invention belongs to the technical field of traditional Chinese medicines and relates to a processing method of a traditional Chinese medicine formulation paris polyphylla direct-oral decoction piece, namely a paris polyphylla freeze-dried powder wall-breaking oral decoction piece, with the effects of clearing away heat and toxic materials and preventing and treating tumors. A finished product is obtained through the following steps of: pretreating; freeze-drying; drying for the second time; crushing; granulating, and the like. The prepared product ensures that the paris polyphylla freeze-dried powder wall-breaking oral decoction piece disclosed by the invention has the advantages of light weight, portability, flexibility in preparation and fast usage, can be used for farthest preserving the drug effect components of an original drug and reducing the property of a crude drug, enhances the quality and drug effect of the paris polyphylla decoction piece, reduces the waste and consumption of paris polyphylla wild resources and improves the utilization ratio of the effective components of paris polyphylla.

A taping tape includes: a base material 12 having elasticity; an adhesive layer attached to one side of the base material 12; and plural slits 14 that are formed along one direction on an inner side of the base material 12 and are arranged parallel to each other. Both side edge portions 12a and 12b of the base material 12 in the vicinities of end portions of the slits 14 are formed obliquely to each other towards a longitudinal direction center of the base material 12 from the vicinities of the end portions of the slits 14 to base material end portions 12c and 12d positioned on extensions of the slits 14. The end portions of the slits 14 curve towards the center of the base material 12 along the side edge portions 12a and 12b.

Compositions and methods of using SerpinF2-binding molecules for preventing and / or reducing organ damage, functional disability or mortality in a patient at risk due to the activity of SerpinF2 and / or plasminogen activators on tissue injury. Also provided are compositions and methods of using SerpinF2-binding molecules for inhibiting hemorrhage, edema, and apoptosis. Methods for the preparation of medicaments for such methods of treatment and prevention are provided.

According to the present invention, a network device includes a plurality of ports which are connected to a LAN; a communication controller; and a communication shutoff release unit. The communication controller includes: a linkup detection unit, a loop detection frame sending out unit that sends out the loop detection frame from a linkup detected port, which is a port for which the linkup is detected, after a predetermined period from a time point when the linkup is detected by the linkup detection unit to the local area network, and a loop detection frame detection unit that detects the loop detection frame if the loop detection frame is received on the each port. The communication shutoff release unit releases the shutoff of the communication on the linkup detected port only if the loop detection frame is not detected by the loop detection frame detection unit.

A vehicle communication system includes: a control device 10B provided in a vehicle; and a management device 50 that is provided in a battery 20 mounted on the vehicle while communicably connected to the control device 10B. One of the control device 10B and the management device 50 discriminates a communication specification of the other and switches the communication specification. In this configuration, consistency of the communication specification is attained between the control device 10B of the vehicle and the battery 20, so that disability of communication between the control device 10B and the battery 20 can be prevented.

The invention discloses an intelligent integrated circuit (IC) card water meter outer box which comprises an upper cover (1) and a box body (2). An IC card water meter body is located inside the box body (2). The upper cover (1) and the IC card water meter body are arranged in a separated mode. An observation opening (3) is formed in the front portion of the upper cover (1). A fixed type card swiping area (4) is arranged on the surface of the rear portion of the upper cover (1). A card groove (5) is formed in the card swiping area (4). The card groove (5) corresponds to the size of an IC card. The intelligent IC card water meter outer box not only can protect the water meter, but also can accurately read out data and keep the cleaning of an intelligent water meter.

The invention discloses a clinical condition evaluation new system for predicting a one-year joint destruction progress of a rheumatoid arthritis patient. According to the invention, a new index whichcan be used for predicting the one-year joint destruction progress of the rheumatoid arthritis patient is researched, namely a limb muscle index (ASMI), and the clinical condition evaluation new system for predicting the one-year joint destruction progress of the rheumatoid arthritis patient is established based on the limb muscle index. The system can accurately screen the high-risk patient, themiddle-risk patient and the low-risk patient in the one-year joint destruction progress earlier than prior art for nine months to one year, and different treatment plans are utilized for the high-risk patient, the middle-risk patient and the low-risk patient, thereby realizing intensive treatment of the high-risk patient and the middle-risk patient earlier for nine months to one year, guiding clinical medicine taking for more effectively reducing or blocking the joint destruction progress of the rheumatoid arthritis patient, preventing disability, and realizing important meaning and high value in treatment controlling and monitoring of rheumatoid arthritis.

The invention discloses one group of primers for detecting FVIII / FIX gene mutations of a patient with hemophilia and application of one group of primers. The primers are 8 pairs of F9 primers, 39 pairs of 22 inversion 3 F8 primers and 1 inversion 4 F8 primers, can be used for etiological classification of hemophilia, can be applied to treatment of a non-factor drug to the hemophilia according to etiological classification of the hemophilia and can enable the patient with the hemophilia to change from severe type to a moderate type and a mild type. By adopting the primers, an acquired getter FVIII / FIX:C can be returned mormality; and further verified that the hemophilia etiological classification method provided by the invention is definite and reliable, opens up a new thought and a new wayof preventing hemophilia bleeding and avoiding disability and has an important significance of guiding prenatal and postnatal care and blocking inheritance.

The invention relates to the technical field of meat duck cage culture, in particular to a safe and efficient duck catching method in a duck shed. According to the safe and efficient duck catching method for the duck shed, duck catching operation is realized through nondestructive cage door opening hooks, a duck-catching slow-down platform mechanism, a duck catching trolley for movement and a duckpushing plate, so that the duck catching time is greatly shortened; and meat ducks in duck cages on the left and right sides simultaneously slide down along a sliding plate of the duck-catching slow-down platform mechanism at the middle of the duck shed, and the time from opening the cage door to completing duck catching and closing the cage door is about 30-40s, so that the duck catching processis greatly shortened, and manpower and material resources are saved.

The invention discloses a system for predicting one-year joint damage progress of a rheumatoid arthritis patient. The system comprises an immunopathology marker score determination module, an optimized synovial membrane cellular immunology score calculation module, a joint damage progress risk comparison module and a risk result display module. According to the system, the cell immunological scoreof the synovial membrane with the optimized evaluation index constructed by immunopathology markers related to the synovial membrane is used as the prediction index for the first time to predict thecondition of one-year joint damage progress of rheumatoid arthritis patients, and high-risk patients with the joint damage progress can be accurately screened out one year in advance; high-risk patients can be subjected to intensive treatment one year ahead of time, so that the joint damage progress of the patients can be effectively reduced or blocked, and the method has important significance and clinical value for accurate treatment of RA and reduction of disability rate.

A vehicle communication system includes: a control device 10B provided in a vehicle; and a management device 50 that is provided in a battery 20 mounted on the vehicle while communicably connected to the control device 10B. One of the control device 10B and the management device 50 discriminates a communication specification of the other and switches the communication specification. In this configuration, consistency of the communication specification is attained between the control device 10B of the vehicle and the battery 20, so that disability of communication between the control device 10B and the battery 20 can be prevented.

The invention belongs to the field of ankle rehabilitation training, and especially discloses ankle rehabilitation training apparatus for patients with gout. In order to solve the problem of unable meeting of needs of use caused by necessity of frequent manual rehabilitation training by accompanying personnel at present, the invention discloses a scheme as follows: the ankle rehabilitation training apparatus for the patients with gout comprises an apparatus body which adopts a hollow structure; a fixing groove is formed at a bottom end of an inner wall of the apparatus body; an iron block is provided inside the fixing groove in a movable way; a mounting base is connected with a top end of the iron block, and extends outside the fixing groove; the iron block is provided with a spring on oneside far away from the mounting base; one end of the spring, which is far away from the iron block, is arranged on an inner-wall bottom end of the fixing groove; a magnet is provided on one side of an inner wall of the fixing groove; and a movable plate is provided on the iron block on one side far away from the magnet. The ankle rehabilitation training apparatus for the patients with gout is rational in structure, and capable of realizing rehabilitation training of bare feet from multiple angles; and moreover, the ankle rehabilitation training apparatus is also capable of avoiding disabilityof the patients caused by non-flowing of the blood, thereby meeting the needs of use.