38results about How to "No potential side effects" patented technology

The invention provides a preparation method and application of green tea essence for cigarette dropping pills. The preparation method of the green tea essence comprises the steps that a green tea aroma component in green tea is extracted through supercritical fluid, olive oil is added to so as to fully dissolve the green tea aroma component, and after filtering, a first component is obtained; an ethanol solution and citric acid are added to the green tea obtained after supercritical fluid extraction for reflux extraction twice, filter liquors are combined, decompressing concentration is conducted, and then a second component 2 is obtained; Span80 is added to the first component, so that a phase A is obtained; the second component, water, glycerol, Tween80 and carbomer are evenly stirred, so that a phase B is obtained; the phase A and the phase B are heated respectively, the phase A is slowly added to the phase B for homogenization, after the pH value is added, a vitamin C aqueous solution is added, and then the green tea essence for the cigarette dropping pills is obtained. The prepared green tea fragrance is of an oil-in-water system, the active component, tea polyphenol, of the green tea is added to the water phase, and the potential toxic and side effects of a compound are avoided; and no off-odor exists, and when applied to cigarette filter tips, the green tea essence has the anti-oxidation function and can remove free radicals in smoke.

The invention discloses an anti-browning method for fresh-cut yams, which comprises the following steps: cleaning, slicing and sterilizing yams without diseases and pests, soaking in the processing liquid for 5-10 min, then removing the surface moisture, and packaging, refrigerating or performing distribution and sales, wherein the processing liquid is the tea polyphenol water solution, tea polyphenol ethanol water solution or ethanol water solution brewed by tea leaves. The anti-browning method adopts tea polyphenol as the main processing liquid, which has a strong anti-oxidation effect with less use amount and great effect, has no potential toxic side effect of compounds, and can protect pigment and vitamins in food, so that the food can keep the original color, luster and nutritional level in a longer time.

The invention discloses a natural color-preserving reducing agent for a sausage casing. The invention is characterized in that the natural color-preserving reducing agent comprises the following formula in percentage by weight: 60-90 percent of tea polyphenol solution with concentration of 40 percent; 5-20 percent of ascorbic sodium salt; 0-10 percent of D-cysteine; and 5-10 percent of citric acid. The invention has the advantages that the natural color-preserving reducing agent adopts the natural tea polyphenol as a main component and has no potential toxic-side effects of synthetics; and catechin plays the role of protecting pigment and vitamins in food, therefore, the sausage casing can keep the original color and nutritional level for a long time, and the odor can be removed.

The invention belongs to the technical field of medicines and particularly relates to a novel pyridine derivative shown, stereoisomers of the pyridine derivative, pharmaceutically acceptable salts of the pyridine derivative, solvates of the pyridine derivate in the general formula (I) and intermediates shown in the general formulas (I') and (II), wherein R1, R2, R3, R4, R5 and n are as defined in a specification; the invention also relates to preparation methods for the compounds, a medicine combination containing the medicine compounds, and the application of the compounds in medicines for preventing and / or treating peptic ulcers, ulcer bleeding and diseases related to gastric acids.

The invention discloses a preparation method of a mask containing water-soluble cannabidiol (CBD). The mask is prepared from the water-soluble cannabidiol with specific active ingredients, epidermal growth factor, a transdermal absorption promoter, collagen, a humectant, a preservative, a thickener and a solubilizer. According to the method, the anti-oxidation, antibacterial, anti-inflammation andantiallergic effects of cannabidiol are reasonably utilized, other effective components in the formula are also used, and a proper proportion is selected, so that the mask product has antioxidant, anti-aging, antibacterial, anti-inflammation, acne-removing, antiallergic, moisturizing and water supplementing effects and the like. Meanwhile, the mask is prepared by adding the water-soluble CBD through a special technology, and the water solubility is extremely high, so that the effect of the CBD is brought into full play.

The invention belongs to the pharmaceutical technical field and specifically relates to new naphthyridine imidazole derivatives which are shown in general formula (I), acceptable salts in pharmacy and isomers thereof, wherein, R, R, R, R and R are defined as in the specification. The invention also relates to preparation methods of the compounds, drug compositions containing the compounds and the application of the compounds in preparing drugs for preventing and / or treating digestive ulcer.

The invention belongs to the pharmaceutical technical field and specifically relates to hydrosulphonyl benzoglioxaline derivatives which are shown in general formula (I) and contain dioxo heptane pyridine, isomers and pharmaceutically acceptable salts thereof, wherein, R, R and R are defined as in the specification. The invention also relates to preparation methods of the compounds, drug compositions containing the compounds and the application of the compounds in preparing drugs for preventing and / or treating digestive ulcer.

The invention belongs to the pharmaceutical technical field and specifically relates to benzoglioxaline derivatives which are shown in general formula (I) and contain naphthyridine tetrahydrochysene isoxazole substituted by alcoxyl ethide, pharmaceutically acceptable salts and isomers thereof, wherein, R, R and R are defined as in the specification. The invention also relates to preparation methods of the compounds, drug compositions containing the compounds and the application of the compounds in preparing drugs for preventing and / or treating digestive ulcer.

The invention relates to a sauce bag of instant nutritional congee and a preparation technology thereof. The sauce bag comprises 50-60kg of edible oil, 8-12kg of sesame oil, 10-12kg of lean pork, 10-12kg of onion, 5.0-8.0kg of leek, 8.0-13kg of garlic, 3.5-5.5kg of ginger, 3.8-4.5kg of cooking wine, 1.5-3.5kg of table salt, 0.1-0.5kg of anise powder, 0.2-0.4kg of cassia bark powder, 3.0-5.0kg of light soy sauce, 3.0-6.0kg of pork essence paste, and 0.02-0.04kg of tea polyphenol. The preparation technology comprises the following steps of cleaning the above raw materials, carrying out chopping or crushing, carrying out heating frying in a steam interlayer pot, and carrying out grinding by a colloid grinding machine to obtain colloidal sauce. Through utilization of the natural anti-oxidant tea polyphenol, food and edible oil spoilage is effectively prevented; a shelf-life is prolonged; and a peculiar smell is eliminated. Through utilization of leek, garlic, ginger, cooking wine, table salt, anise powder and cassia bark powder, a sauce local flavor and a sauce taste are improved.

The invention belongs to the technical field of medicines, and in particular relates to a benzimidazole derivative containing pyridine substituted by alkoxy as well as pharmaceutically acceptable salts or isomers thereof shown in a general formula (I), wherein R, R, R, R, R and n are defined as the specification. The invention also relates to a method for preparing the compounds and a pharmaceutical composition containing the compounds, and application of the compounds to preparing the medicines for treating and / or preventing peptic ulcer.

The invention discloses tea polyphenol grape wine and a preparation method thereof. The tea polyphenol grape wine is mainly prepared from the following raw materials in parts by weight: 100 to 150 parts of fresh grape, 15 to 20 parts of tea, 30 to 60 parts of maltose, and 100 to 200 parts of water. As the effective component tea polyphenol of tea is added into grape wine, the tea polyphenol grapewine has the efficacies of maintaining beauty and keeping young, oxidation resistance and ageing resistance.

The invention provides a preparation method and application of green tea essence for cigarette dropping pills. The preparation method of the green tea essence comprises the steps that a green tea aroma component in green tea is extracted through supercritical fluid, olive oil is added to so as to fully dissolve the green tea aroma component, and after filtering, a first component is obtained; an ethanol solution and citric acid are added to the green tea obtained after supercritical fluid extraction for reflux extraction twice, filter liquors are combined, decompressing concentration is conducted, and then a second component 2 is obtained; Span80 is added to the first component, so that a phase A is obtained; the second component, water, glycerol, Tween80 and carbomer are evenly stirred, so that a phase B is obtained; the phase A and the phase B are heated respectively, the phase A is slowly added to the phase B for homogenization, after the pH value is added, a vitamin C aqueous solution is added, and then the green tea essence for the cigarette dropping pills is obtained. The prepared green tea fragrance is of an oil-in-water system, the active component, tea polyphenol, of the green tea is added to the water phase, and the potential toxic and side effects of a compound are avoided; and no off-odor exists, and when applied to cigarette filter tips, the green tea essence has the anti-oxidation function and can remove free radicals in smoke.

The invention belongs to the pharmaceutical technical field and specifically relates to hydrosulphonyl benzoglioxaline derivatives which are shown in general formula (I) and contain dihydrofuran pyridine, pharmaceutically acceptable salts and isomers thereof, wherein, R, R, R and R are defined as in the specification. The invention also relates to preparation methods of the compounds, drug compositions containing the compounds and the application of the compounds in preparing drugs for preventing and / or treating digestive ulcer.

The present invention relates to benzimidazole derivatives and their pharmaceutical compositions and uses, specifically to benzimidazole derivatives of Formula (I), or their stereoisomer, pharmaceutically acceptable salt or solvates thereof, in which R 1 , R 2 , R 3 , R 4 , R 5 and n have the definitions in the description; the present invention further relates to a pharmaceutical composition containing the compounds, methods for preparing the compounds, and use of the compounds for manufacturing of a medicament for prophylaxis and / or treatment of peptic ulcer, ulcer hemorrhage and diseases associated with gastric acid.

The invention belongs to the technical field of medicine, and in particular relates to compounds which are shown in a general formula (I) and contain imidazopyridine, pharmaceutically acceptable salts of the same and isomers of the same, wherein R, R, R, and X are defined in a specification. The invention also relates to a method for preparing the compounds, a pharmaceutical composition containing the compounds, and application of the compounds to preparation of medicines for preventing and / or treating peptic ulcer.

The invention belongs to the pharmaceutical technical field and specifically relates to hydrosulphonyl benzoglioxaline derivatives which are shown in general formula (I) and contain dioxo heptane pyridine, isomers and pharmaceutically acceptable salts thereof, wherein, R<1>, R<2> and R<3> are defined as in the specification. The invention also relates to preparation methods of the compounds, drugcompositions containing the compounds and the application of the compounds in preparing drugs for preventing and / or treating digestive ulcer.

The invention belongs to the pharmaceutical technical field and specifically relates to benzoglioxaline derivatives which are shown in general formula (I) and contain naphthyridine tetrahydrofuran substituted by alcoxyl ethide, pharmaceutically acceptable salts and isomers thereof, wherein, R, R and R are defined as in the specification. The invention also relates to preparation methods of the compounds, drug compositions containing the compounds and the application of the compounds in preparing drugs for preventing and / or treating digestive ulcer.

The invention belongs to the technical field of medicine, and in particular relates to compounds of imidazopyridine which are shown in a general formula (I) and contain aminooxy substituted pyridine, pharmaceutically acceptable salts of the same and isomers of the same, wherein R, R, R and R are defined in a specification. The invention also relates to a method for preparing the compounds, a pharmaceutical composition containing the compounds, and application of the compounds to preparation of medicines for preventing and / or treating peptic ulcer.

The invention belongs to the pharmaceutical technical field and specifically relates to imidazopyridine derivatives which are shown in general formula (I) and contain dioxide heterocyclic pyridine, pharmaceutically acceptable salts and isomers thereof, wherein, R<1>, R<2>, R<3> and n are defined as in the specification. The invention also relates to preparation methods of the compounds, drug compositions containing the compounds and the application of the compounds in preparing drugs for preventing and / or treating digestive ulcer.

The invention belongs to the technical field of medicine, and in particular relates to pyridinemethylsulfinyl imidazopyridine derivatives shown in a general formula (I), pharmaceutically acceptable salts of the same and isomers of the same, wherein R, R, R, X and Y are defined in a specification. The invention also relates to a method for preparing the compounds, a pharmaceutical composition containing the compounds, and application of the compounds to preparation of medicines for treating peptic ulcer.

The invention belongs to the pharmaceutical technical field and specifically relates to benzoglioxaline derivatives which are shown in general formula (I) and contain naphthyridine tetrahydrochysene isoxazole substituted by alcoxyl alkyl, pharmaceutically acceptable salts and isomers thereof, wherein, R, R and R are defined as in the specification. The invention also relates to preparation methods of the compounds, drug compositions containing the compounds and the application of the compounds in preparing drugs for preventing and / or treating digestive ulcer.

The invention belongs to the pharmaceutical technical field and specifically relates to dihydro isoxazole pyridine derivatives which are shown in general formula (I) and contain alcoxyl acetyl, pharmaceutically acceptable salts and isomers thereof, wherein, R, R, R and R are defined as in the specification. The invention also relates to preparation methods of the compounds, drug compositions containing the compounds and the application of the compounds in preparing drugs for preventing and / or treating digestive ulcer.

The invention belongs to the pharmaceutical technical field and specifically relates to sulfhydryl imidazopyridine derivatives which are shown in general formula (I) and contain diosulberane pyridine, isomers and pharmaceutically acceptable salts thereof, wherein, R<1>, R<2> and R<3> are defined as in the specification. The invention also relates to preparation methods of the compounds, drug compositions containing the compounds and the application of the compounds in preparing drugs for preventing and / or treating digestive ulcer.

The invention belongs to the technical field of medicine, and in particular relates to pyridinemethylsulfinyl imidazopyridine derivatives shown in a general formula (I), pharmaceutically acceptable salts of the same and isomers of the same, wherein R<1>, R<2>, R<3>, X and Y are defined in a specification. The invention also relates to a method for preparing the compounds, a pharmaceutical composition containing the compounds, and application of the compounds to preparation of medicines for treating peptic ulcer.

The invention belongs to the technical field of medicines, and in particular relates to a benzimidazole derivative containing pyridine substituted by alcoxyl and alkanamine oxygroup as well as pharmaceutically acceptable salts or isomers thereof shown in a general formula (I), wherein R<1>, R<2>, R<3>, R<4>, R<5> and n are defined as the specification. The invention also relates to a method for preparing the compounds and a pharmaceutical composition containing the compounds, and application of the compounds to preparing the medicines for treating and / or preventing peptic ulcer.

The invention belongs to the pharmaceutical technical field and specifically relates to benzoglioxaline derivatives which are shown in general formula (I) and contain isoxazole pyridine, pharmaceutically acceptable salts and isomers thereof, wherein, R, R, R and R are defined as in the specification. The invention also relates to preparation methods of the compounds, drug compositions containing the compounds and the application of the compounds in preparing drugs for preventing and / or treating digestive ulcer.

The invention belongs to the technical field of medicines, and in particular relates to a benzimidazole derivative containing pyridine substituted by alcoxyl and alkanamine oxygroup as well as pharmaceutically acceptable salts or isomers thereof shown in a general formula (I), wherein R, R, R, R, R and n are defined as the specification. The invention also relates to a method for preparing the compounds and a pharmaceutical composition containing the compounds, and application of the compounds to preparing the medicines for treating and / or preventing peptic ulcer.