Soluble effervescent preparations
An effervescent preparation and soluble technology, applied in the field of pharmaceutical preparations, can solve the problems of loss of nutrients, weak foaming ability, and decreased pure calcium content, and achieve the effects of stable properties, helpful absorption and broad application prospects.
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[0014] Example 1:
[0015] Pearl powder, citric acid and sodium bicarbonate are mixed according to the following weight ratios to form a soluble pearl effervescent powder preparation:
[0016] Pearl powder 50g
[0017] Sodium bicarbonate 25g
[0018] Anhydrous citric acid 75g
[0019] The above powder can also be filled into capsule preparations. Dissolve it in an appropriate amount of water before taking it, and form a clear solution after standing for 3 to 8 minutes, and take it orally or drink it directly.
Example Embodiment
[0020] Example 2:
[0021] After mixing 50g of pearl powder, 75g of anhydrous citric acid and 25g of sodium bicarbonate, the ethanol solution of the binder containing crospovidone is added to the mixture, granulated, dried to make granules or compressed into tablets.
Example Embodiment
[0022] Example 3:
[0023] Pearl powder 50g
[0024] Sodium bicarbonate 25g
[0025] Citric acid 75g
[0026] Crospovidone or starch 4g
[0027] Anhydrous ethanol amount
[0028] Mix the above 1 / 2 amount of pearl powder and sodium bicarbonate, add an appropriate amount of cross-linked povidone binder ethanol solution; take another 1 / 2 amount of pearl powder and mix it with citric acid, add the remaining amount of cross-linked povidone The ethanol solution of the binder is granulated separately, dried at low temperature, and then the two dry granules are mixed evenly to obtain granules, which can be tableted after tableting.
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