Soluble effervescent preparations

Abstract

The present invention relates to a soluble effervescence preparation which comprises powder, granular preparation, tablet or capsule, in particular to a medicine or food preparation which takes pearl as active component, which belongs to the technical field of medication preparation. The present invention takes pearl powder as the active component and takes sodium bicarbonate and citric acid as effervescence substrate, which also comprises accessory ingredient which is not necessary and is acceptable in medicine. Counted by weight, the proportion of the pearl powder, the sodium bicarbonate and the citric acid is 1-5:0.25-50:0.25-50. Certain quantity of water is added, the meta acid solution which is formed by a great deal of bubbles generated by acid-base interaction of three components can dissolve the pearl powder with the insoluble alkali component into clear solution, so as to be directly taken orally or drunk and has the advantages of stable characteristic, not losing nutrient component of the pearl powder, being helpful for being absorbed, not increasing the burden of digestive system, convenient use etc. The present invention provides a novel approach for taking the pearl powder and is ideal medicine and nutrient product preparation, which has very wide application prospect.

Description

technical field [0001] The invention relates to a soluble effervescent preparation, including powder, granule, tablet or capsule, in particular to a medicine or food preparation with pearl as an active ingredient, belonging to the technical field of pharmaceutical preparations. Background technique [0002] Pearls can be divided into freshwater pearls and seawater pearls in terms of resources and varieties; in terms of acquisition methods, they can be natural wild or artificially cultivated. Pearls are rich in nutrients and various sources of life. As a traditional Chinese medicine, it has been used in my country for thousands of years. It has the functions of calming the nerves, nourishing yin and wind, improving eyesight and eliminating cloudiness, detoxifying and promoting muscle growth. Diabetes, dizziness, tinnitus, red eyes and cloudy eyes, etc., externally treat sores without constricting the mouth, and can also cure facial chloasma, making the skin moist and tender, ...

AI Technical Summary

Problems solved by technology

According to composition wherein calcium carbonate reacts with acetic acid and hydrochloric acid to generate soluble calcium acetate or calcium chloride etc., calcium ion forms and exists, and the main deficiency of the existence of said method is: the pure calcium content declines in the calcium chloride or calcium acetate that forms, And oral administration has certain irritation to the human gastrointestinal tract, so it is not an ideal oral preparation

At the same time, some nutrients such as trace elements, proteins and essential amino acids are lost to varying degrees after being filtered during the preparation of soluble hydrolyzate.

[0005] Publication No. CN1138529C Chinese Invention Patent "Effervescent Preparation" discloses a technique for preparing effervescent preparations of selegiline using calcium carbonate and citric acid as effervescent bases, wherein the effervescent base used is commonly used in pharmacy An effervescent base of calcium carbonate and / or magnesium carbonate and citric acid, which has weak foaming ability and weak solubility for insoluble ingredients

Since the main component of pearl powder is calcium carbonate, which belongs to alkaline earth metal and has weak alkalinity, it reacts with citric acid alone to form calcium citrate, which needs to add a high proportion of citric acid, and it is difficult to form a soluble solution. Therefore, it cannot effectively Applied to the preparation of insoluble alkaline ingredients pearl powder oral effervescent preparations