Method for producing 3-hydracrylic acid

A technology of hydroxypropionic acid and amino acid, applied in the field of production of 3-hydroxypropionic acid, which can solve problems such as difficult large-scale production and large-scale production
CN101445813AInactive Publication Date: 2009-06-03TSINGHUA UNIV
7 Cites 8 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
TSINGHUA UNIV
Publication Date
2009-06-03
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses a method for producing 3-hydracrylic acid. The method is characterized by taking 1,3-propylene glycol as a raw material, and producing the 3-hydracrylic acid by microbes which express 1,3-propylene glycol dehydrogenase and aldehyde oxidase. The microbes which express the 1,3-propylene glycol dehydrogenase and the aldehyde oxidase are microbes which naturally express the 1,3-propylene glycol dehydrogenase and the aldehyde oxidase, or recombinant microbes which can express the 1,3-propylene glycol dehydrogenase and the aldehyde oxidase and are obtained by transferring coding gene of 1,3-propylene glycol dehydrogenase and coding genes of the aldehyde oxidase into a microbe host. By the method, the 1,3-propylene glycol is taken as the raw material, content of the 3-hydracrylic acid per liter of a culture medium is up to 0.24-12.1g.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The present invention relates to a method for producing 3-hydroxypropionic acid. Background technique

[0002] 3-Hydroxypropionic acid (3HP) is a viscous liquid with a logarithmic acid dissociation constant (pKA) of 4.5 in water, easily soluble in water and ethanol, and miscible with ether (Merck Index, 11 th Edition, 4681). 3HP has a wide range of applications, and can be used as a precursor for chemical synthesis and drug synthesis to produce coatings, adhesives, water treatment chemicals, and personal skin care products. Currently reported chemical products that can be synthesized from 3HP include Ethyl ethoxy propionate (EEP), acrylamide compounds, acrylates, acrylic acid polymers, and 1,3-malonic acid. 3HP can also be used as a precursor for the synthesis of ultra-high-performance polyester plastic PHP and a high-performance monomer component precursor for the synthesis of high-performance biodegradable plastic polyhydroxyalkanoate (PHA) (MattC...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More