Method for extracting hesperidin from tangerine peel

A technology of hesperidin and tangerine peel, applied in the field of extraction and separation of hesperidin, which can solve the problems of large amount of ethanol, high production cost, and long time consumption, and achieve high extraction rate and content of products, short production cycle and simple process Effect

Active Publication Date: 2010-06-23
ZHEJIANG UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above method has the following disadvantages: the heat reflux method has a large amount of ethanol and high production cost; the solvent immersion method takes a long time and the content of hesperidin in the product is low; the water extraction method consumes a lot of energy, the extraction rate and the content of hesperidin are low; The method needs to use strong alkali to extract, and the dosage is large, time-consuming, and it is highly corrosive to production equipment, so it is difficult to apply to industrial production
At present, there is no relevant report on the extraction of hesperidin by mechanochemical technology

Method used

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  • Method for extracting hesperidin from tangerine peel

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Mix 5.0g tangerine peel powder with 7.5g sodium bicarbonate and grind together to powder particle size D 90 37 μm (detected by a particle size analyzer, the same below), take out the grinding powder, add 100ml of water, centrifuge after fully stirring, take the supernatant, add acetic acid to adjust the pH value to 5.0, filter after standing, the filter cake is a white precipitate, dry , that is, 0.2714g of hesperidin product was obtained, with a yield of 5.43% and a content of 90.60%.

Embodiment 2

[0033] Mix 5.0g tangerine peel powder with 10.0g potassium bicarbonate and grind together to powder particle size D 90 68μm, take out the grinding powder, add 300ml of water, centrifuge after fully stirring, take the supernatant, add acetic acid to adjust the pH value to 6.0, filter after standing, the filter cake is a white precipitate, dry, and obtain the hesperidin product 0.2658g , the yield was 5.32%, and the content was 91.57%.

Embodiment 3

[0035] Mix 5.0g tangerine peel powder with 5.0g potassium carbonate and grind together to powder particle size D 90 53μm, take out the ground powder, add 200ml of water, centrifuge after fully stirring, take the supernatant, add 6mol / L hydrochloric acid to adjust the pH value to 3.0, let stand and filter, the filter cake is white precipitate, dry, and orange peel is obtained The glycoside product is 0.2636g, the yield is 5.27%, and the content is 90.97%.

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Abstract

The invention discloses a method for extracting hesperidin from tangerine peel. The method comprises: mixing tangerine peel with a solid-phase alkali reagent, wherein the tangerine peel is tangerine peel powder which is ground to have a powder particle size analysis result D90 between 10 and 200 mu m; adding water, stirring, centrifuging and taking supernatant; adding acid to regulate pH between 2.0 and 6.0; standing and then filtering the obtained product; drying a filter cake; and obtaining hesperidin. The solid-phase alkali reagent is one or arbitrary mixture of more than two of sodium hydroxide, aluminum hydroxide, calcium hydroxide, potassium hydroxide, sodium bicarbonate, potassium bicarbonate, sodium carbonate, potassium carbonate, calcium carbonate, sodium silicate, disodium hydrogen phosphate or dipotassium hydrogen phosphate. By adopting a mechanochemical technique to extract and separate the hesperidin, the method has the advantages of high extraction rate, high product purity, simple process, environment-friendly property, low cost and short production cycle, and is an extraction-separation route with broad industrialization prospects.

Description

(1) Technical field [0001] The invention relates to a method for extracting and separating hesperidin, in particular to a method for extracting and separating hesperidin from tangerine peel by using mechanochemical technology. (2) Background technology [0002] Tangerine peel is the dry and mature peel of Rutaceae plant orange and its cultivars. Dried tangerine peel tastes pungent, bitter, warm in nature, enters the spleen and lung meridians, and has the effect of "regulating qi and invigorating the spleen, drying dampness and resolving phlegm". It is mainly used to treat diseases of the digestive system and respiratory system. It is the most commonly used drug for tract diseases, which can treat abdominal fullness, belching, pantothenic acid, nausea and vomiting, constipation or diarrhea, etc. Chenpi mainly contains volatile oil, flavonoids, organic amines and trace elements. Among them, flavonoids (3.6%-10.0%) are mainly hesperidin (3.4%-8.7%), neohesperidin, nobiletin, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07H17/07C07H1/08
Inventor 谢捷王平苏为科朱兴一曹铭希
Owner ZHEJIANG UNIV OF TECH
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