Traditional Chinese medicament for treating organic phosphorus pesticide poisoning and preparation method thereof

A technology of organophosphorus pesticides and traditional Chinese medicines, applied in the field of pharmacy, can solve the problems of relatively few studies on the law of organophosphorus pesticide poisoning syndrome differentiation and treatment, can not stop muscle tremors, spasms and relieve paralysis, and threaten the life safety of patients, so as to enhance the defense against diseases. Evil ability, improved cure rate, less side effects

Inactive Publication Date: 2014-11-05
李凡旺
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Western medicine treatment of organophosphorus pesticide poisoning cholinergic nerve inhibitors such as atropine and anisodamine have no effect on nicotine-like effects, nor can they revive cholinesterase, so they cannot stop muscle tremors, spasms, and relieve paralysis. There are many adverse reactions, and the dosage is not easy to control. If the dosage of the drug is not well grasped, it will directly thre

Method used

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Examples

Experimental program
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preparation example Construction

[0087] Wherein, when the dosage form of Chinese medicine is honey refining pill, its preparation method comprises the following steps:

[0088] Step 1: First mix mulberry leaves, reed roots, bamboo leaves, scutellaria baicalensis, coptis, gentian, horsetail, andrographis paniculata, Folium Folium, chrysanthemum and boxing ginseng according to the stated ratio, and distill and crystallize to obtain powder;

[0089] Step 2: Take the remaining raw materials and mix them according to the ratio, add 2-6 times the amount of 83-94% ethanol to soak for 1-2 hours, heat and extract twice, each time for 1-1.5 hours, and combine the extracts , 124-150 mesh filtration, and then ultrafiltration through an ultrafiltration column with a cut-off molecular weight of 4400-98000, and the ultrafiltrate is concentrated under reduced pressure to an extract with a relative density of 1.04 at 87°C, which becomes component 1;

[0090] Step 3: Soak the dregs of the traditional Chinese medicine in step 2...

Embodiment 1

[0104] Embodiment 1 honey refining pill of the present invention

[0105] Take 17g of mulberry leaves, 32g of reed root, 16g of bamboo leaves, 30g of skullcap, 14g of berberine, 31g of gentian, 25g of horsetail, 32g of Andrographis paniculata, 35g of Daqingye, 11g of chrysanthemum, 11g of ginseng, 20g of green fruit, and 30g of golden fruit olive , lobelia 29g, wood butterfly 24g, mung bean 24g, habitat 8g, scrophulariaceae 26g, buffalo horn 29g, genkwa 39g, rhubarb 17g, aloe vera 16g, mulberry branch 24g, weasel 21g, coix seed 11g, shepherd's purse 32g, cinnamon 30g, Qingmuxiang 33g, Sala seed 18g, Dabupipi 20g, Cat's Claw 26g, Ganoderma lucidum 15g, Mother of Pearl 12g, Antelope Horn 36g, Bezoar 25g, Uncaria 10g, Earthworm 12g, Centipede 10g and borneol 5g.

[0106] Its preparation method comprises the following steps:

[0107] Step 1: First mix mulberry leaves, reed roots, bamboo leaves, scutellaria baicalensis, coptis, gentian, horsetail, andrographis paniculata, Folium F...

Embodiment 2

[0112] Embodiment 2 Granules of the present invention

[0113] Take 33g of mulberry leaves, 36g of reed root, 13g of bamboo leaves, 25g of Scutellaria baicalensis, 10g of berberine, 27g of gentian, 38g of horsetail, 18g of Andrographis paniculata, 29g of Daqingye, 10g of Chonglou, 21g of ginseng, 14g of green fruit, and 18g of golden fruit olive , lobelia 30g, wood butterfly 19g, mung bean 32g, habitat 5g, scrophulariaceae 18g, buffalo horn 36g, Daphne genkwa 31g, rhubarb 21g, aloe vera 23g, mulberry branch 35g, weasel 19g, coix seed 17g, shepherd's purse 35g, cinnamon 37g, Qingmuxiang 26g, Salazi 29g, Dabupi 23g, Cat's Claw 36g, Ganoderma lucidum 20g, Mother of Pearl 23g, Antelope Horn 31g, Bezoar 37g, Uncaria 14g, Earthworm 17g, Centipede 6g and Borneol 9g.

[0114] Its preparation method comprises the following steps:

[0115]Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 95% that is 6 times that of the m...

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Abstract

The invention discloses a traditional Chinese medicament for treating organic phosphorus pesticide poisoning and a preparation method thereof. The traditional Chinese medicament is prepared from the following medicinal materials: folium mori, rhizoma phragmitis, bamboo leaf, scutellaria baicalensis, coptis chinensis, radix gentianae, meadowrue root and rhizome, andrographis paniculata, folium isatidis, rhizoma paridis, bistort rhizome, Chinese olive, radix tinosporae, Chinese lobelia, semen oroxyli, phaseolus radiatus, radix rehmanniae recen, radix scrophulariae, cornu bubali, lilac daphne flower bud, rheum officinale, aloe, ramulus mori, herba siegesbeckiae, semen coicis, shepherdspurse herb, cortex cinnamomi, radix aristolochiae, semen aesculi, pericarpium arecae, radix ranunculi ternati, lucid ganoderma, nacre mother of pearl, cornu saigae tataricae, calculus bovis, uncaria rhynchophylla, earthworm, centipede and borneol. The traditional Chinese medicament has the effects of clearing heat and removing toxicity, resolving dampness and restoring consciousness, can be used for treating organic phosphorus pesticide poisoning, is capable of strengthening the pathogenic factor resistance of a body and solidifying and protecting vital energy by utilizing the traditional Chinese medical theory and focusing on the holism concept, has the advantages of strong targeting property, toxin removal, symptom and root cause treatment, few adverse response and short course of treatment by treatment based on syndrome differentiation, and is safe and effective.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine for treating organophosphorus pesticide poisoning and a preparation method thereof. [0002] Background technique [0003] There are many kinds of organophosphorus pesticides. According to their toxicity, they are divided into three categories: high toxicity, poisoning, and low toxicity. Phosphorus (1605) is 3.5-15mg; demeton (1059) is 4-10mg; phorate (3911) is 2.1-3.7mg; diphorate is 4mg; The above are highly toxic). Dichlorvos is 50-110 mg; methyl parathion (methyl 1065) is 14-42 mg; methyl demeton (methyl 1059, 4044) is 80-130 mg (the above are poisonous), trichlorfon is 450- 500mg; dimethoate 230~450mg; malathion (4049, marathon) 1800mg; Highly toxic organophosphorus pesticides can be poisoned by a small amount of contact, and low-toxic organophosphorus pesticides can also cause harm if they enter the body in large quantities. The poisonin...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61P39/02A61K31/045A61K35/32A61K35/413A61K35/56A61K35/64
Inventor 李凡旺杨清
Owner 李凡旺
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