The invention discloses a traditional Chinese medicament for treating organic phosphorus pesticide poisoning and a preparation method thereof. The traditional Chinese medicament is prepared from the following medicinal materials: folium mori, rhizoma phragmitis, bamboo leaf, scutellaria baicalensis, coptis chinensis, radix gentianae, meadowrue root and rhizome, andrographis paniculata, folium isatidis, rhizoma paridis, bistort rhizome, Chinese olive, radix tinosporae, Chinese lobelia, semen oroxyli, phaseolus radiatus, radix rehmanniae recen, radix scrophulariae, cornu bubali, lilac daphne flower bud, rheum officinale, aloe, ramulus mori, herba siegesbeckiae, semen coicis, shepherdspurse herb, cortex cinnamomi, radix aristolochiae, semen aesculi, pericarpium arecae, radix ranunculi ternati, lucid ganoderma, nacre mother of pearl, cornu saigae tataricae, calculus bovis, uncaria rhynchophylla, earthworm, centipede and borneol. The traditional Chinese medicament has the effects of clearing heat and removing toxicity, resolving dampness and restoring consciousness, can be used for treating organic phosphorus pesticide poisoning, is capable of strengthening the pathogenic factor resistance of a body and solidifying and protecting vital energy by utilizing the traditional Chinese medical theory and focusing on the holism concept, has the advantages of strong targeting property, toxin removal, symptom and root cause treatment, few adverse response and short course of treatment by treatment based on syndrome differentiation, and is safe and effective.