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3 results about "Nerve agent" patented technology
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Nerve agents, sometimes also called nerve gases, are a class of organic chemicals that disrupt the mechanisms by which nerves transfer messages to organs. The disruption is caused by the blocking of acetylcholinesterase, an enzyme that catalyzes the breakdown of acetylcholine, a neurotransmitter.
Hydroxy-pyridinaldoxime scaffolds
The present invention relates to a compound of formula (I). It also relates to a pharmaceutical composition comprising at least one compound of formula (I) and at least one pharmaceutically acceptable support. Finally, it relates to the use of such a compound as a medicine, preferably in the treatment of a nervous and / or respiratory failure due to intoxication with at least one organophosphorous nerve agent; in the treatment of neurological diseases such as Alzheimer's disease; and / or in the treatment of cancer.
Owner:CENT NAT DE LA RECH SCI (C N R S) +2
Diazinoximes scaffolds
The present invention relates to a compound of formulas (II) to (V). It also relates to a pharmaceutical composition comprising at least one compound of formulas (II) to (V) and at least one pharmaceutically acceptable support. Finally, it relates to the use of such a compound as a medicine, preferably in the treatment of a nervous and / or respiratory failure due to intoxication with at least one organophosphorus nerve agent by reactivation of hAChE; in the treatment of neurological diseases such as Alzheimer's disease; and / or in the treatment of cancer.
Owner:CENT NAT DE LA RECH SCI (C N R S) +2
An organic fluorescent sensing array for selectively detecting sarin and its preparation method
ActiveCN117304919BEfficient detectionhigh sensitivityOrganic chemistryFluorescence/phosphorescenceFluorescenceChemical compound
This invention relates to an organic fluorescent sensor array for the sensitive and selective detection of sarin using fluorescence methods, and its preparation method. The organic fluorescent sensor material is assembled with compounds of formula (B) and formula (C), which are insensitive to nerve agents, along with the compound of formula (A), to form an organic fluorescent sensor array consisting of material 1 and material 2. This improves upon the poor stability and susceptibility to interference when using compound (A) alone for sarin detection, while maintaining the sensitivity for sarin detection, thus improving the fluorescence stability and anti-interference capability of the detection.
Owner:INST OF CHEM CHINESE ACAD OF SCI