Composition with effects of protecting joints and increasing bone mineral density and preparation method of composition

A technology to increase bone density and protect joints, applied to medical preparations containing active ingredients, drug combinations, applications, etc., can solve problems such as increased bone fragility, prone to bone pain, fractures, and unable to fundamentally solve bone health

Pending Publication Date: 2016-03-02
SHENZHEN TAITAI PHARMA IND +2
View PDF4 Cites 11 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Currently popular sayings include calcium supplementation to prevent and treat osteoporosis, but clinical studies have shown that most osteoporosis patients are not caused by calcium deficiency, and simple supplementation of calcium and other inorganic

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Composition with effects of protecting joints and increasing bone mineral density and preparation method of composition
  • Composition with effects of protecting joints and increasing bone mineral density and preparation method of composition
  • Composition with effects of protecting joints and increasing bone mineral density and preparation method of composition

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0071] Example 1: Preparation of the composition tablet of the present invention

[0072] 1. Raw material composition:

[0073] 330g calcium citrate malate, 220g glucosamine sulfate potassium salt, 160g chondroitin sulfate, 100g collagen peptide powder, 30g casein phosphopeptide.

[0074] 2. The composition of auxiliary materials:

[0075] 50g lactose, 50g copovidone, 40g microcrystalline cellulose, 5g silicon dioxide, 5g magnesium stearate.

[0076] 3. Preparation method:

[0077] (1) Measure the moisture of each raw and auxiliary material, and control the moisture ≤5.0%;

[0078] (2) Pass calcium citrate malate, collagen peptide powder, casein phosphopeptide, lactose, copovidone, and microcrystalline cellulose through a 60 mesh sieve; pass chondroitin sulfate and magnesium stearate through an 80 mesh sieve, press The formula weighs the raw and auxiliary materials;

[0079] (3) Mix glucosamine sulfate potassium salt and silicon dioxide for 5 minutes, pass through an 80-mesh sieve, and mi...

Example Embodiment

[0082] Example 2: Preparation of the composition tablet of the present invention

[0083] 1. Raw material composition:

[0084] 400g calcium citrate malate, 150g glucosamine sulfate potassium salt, 200g chondroitin sulfate, 50g collagen peptide powder, 40g casein phosphopeptide.

[0085] 2. Composition of accessories:

[0086] 70g lactose, 50g copovidone, 30g microcrystalline cellulose, 5g silicon dioxide, 5g magnesium stearate.

[0087] 3. Preparation method:

[0088] (1) Determine the moisture content of each raw and auxiliary material, and control the moisture content ≤5.0%;

[0089] (2) Pass the raw and auxiliary materials through a 60-mesh sieve, and weigh the raw and auxiliary materials according to the formula;

[0090] (3) Mix glucosamine sulfate potassium salt and silica for 30 minutes, and then mix with the above-mentioned other materials that have been screened with an automatic lifting hopper mixer for 45 minutes, then put the materials into the turnover container and weigh th...

Example Embodiment

[0092] Example 3: Preparation of the composition tablet of the present invention

[0093] 1. Raw material composition:

[0094] 250g calcium citrate malate, 300g glucosamine sulfate potassium salt, 100g chondroitin sulfate, 150g collagen peptide powder, 40g casein phosphopeptide.

[0095] 2. Composition of accessories:

[0096] Lactose 30g, copovidone 50g, microcrystalline cellulose 55g, silicon dioxide 5g, magnesium stearate 10g.

[0097] 3. Preparation method:

[0098] (1) Determine the moisture content of each raw and auxiliary material, and control the moisture content ≤5.0%;

[0099] (2) Pass the raw and auxiliary materials through an 80-mesh sieve, and weigh the raw and auxiliary materials according to the formula;

[0100] (3) Mix glucosamine sulfate potassium salt and silicon dioxide for 10 minutes, then mix with the above-mentioned other materials that have been screened with an automatic lifting hopper mixer for 75 minutes, then put the materials into the turnover container and ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Hardnessaaaaaaaaaa
Login to view more

Abstract

The invention provides a composition with effects of protecting joints and increasing bone mineral density. The composition is prepared from the following components in parts by weight: 250-400 parts of calcium citrate malate, 150-300 parts of N-Sulfo-glucosamine potassium salt, 100-200 parts of chondroitin sulfate, 50-150 parts of bone collagen peptide powder, and 10-50 parts of casein phosphopeptides. According to the composition provided by the invention, the active ingredients achieve the synergistic effect, the bioavailability is high, and the composition can be used for increasing the bone mineral density and restoring the bone functions. Through a preparation method provided by the invention, the composition can be prepared into a compound preparation, the curative effects are definite, the quality is controllable, no toxic or side effect exists, and the composition is suitable for large-scale popularization and application.

Description

technical field [0001] The present invention relates to a composition, in particular to a composition with the functions of protecting joints and increasing bone density. Background technique [0002] Osteoporosis (OP) is a systemic skeletal disease characterized by decreased bone mass, damaged bone microarchitecture, increased bone fragility, and susceptibility to fracture. According to the data of the World Health Organization, the incidence rate of osteoporosis is 21% at the age of 50-60, 58% at the age of 60-70, and almost 100% at the age of 70-80, especially in postmenopausal women and elderly men. The incidence rate is higher, and there is a younger trend. In particular, the eating habits of Chinese residents can easily lead to insufficient calcium intake, which in turn leads to an increasingly serious incidence of osteoporosis. Therefore, the prevention and treatment of osteoporosis is imperative. [0003] At present, the etiology and pathogenesis of primary osteop...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K38/39A23L33/00A23L33/125A23L2/38A23L2/39A61P19/10A61P19/02A61K31/737A61K31/7008A61K38/17A61K31/194A61K31/12
CPCA61K38/1709A61K38/39A23L2/38A23L2/39A61K9/1652A61K9/2054A61K9/28A61K31/12A61K31/194A61K31/7008A61K31/737A23V2002/00A61K2300/00A23V2200/306A23V2200/30A23V2250/1628A23V2250/2112A23V2250/51A23V2250/51084A23V2250/55A23V2250/612A23V2250/5114
Inventor 常弘杰余孝云李志明陆宝宝
Owner SHENZHEN TAITAI PHARMA IND
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap