Composition with functions of promoting hair growth, repairing scalp and preserving moisture and preparation method of composition
A composition and efficacy technology, applied in the directions of medical preparations containing active ingredients, hair care, pharmaceutical formulations, etc., can solve the problems of high cost and many components in shampoo formulations, improve stability, and increase skin moisturization. performance, the effect of promoting cell regeneration
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Embodiment 1
[0037] The preparation of embodiment 1 nanoemulsion
[0038] The formula of A-E group nanoemulsion sees the following table:
[0039] components Group A Group B Group C Group D Group E Rice bran oil (%) 5 10 8 6 10 Caprylic triglyceride (%) 5 / 3 / 5 Capric triglyceride (%) / 1 / 5 / Phospholipids (%) 8 1 5 6 8 Sorbitan Oleate (%) 1 8 5 4 8 Phenoxyethanol(%) 1 0.1 0.2 0.5 1 water(%) 80 79.9 78.8 78.5 68
[0040] Preparation:
[0041] (1) Mix rice bran oil, caprylic / capric triglyceride, phospholipids, phenoxyethanol and sorbitan oleate, heat to 70°C, stir while heating until the materials are completely dissolved, and set aside;
[0042] (2) Add water to the dissolved material in step (1), and stir for 4 minutes under the condition that the rotating speed is 500r / min, to prepare a coarse emulsion;
[0043] (3) When the temperature of the crude emulsion is lowered to 40°C, add the crud...
Embodiment 2
[0044] Embodiment 2 nanoemulsion quality detection
[0045] The average particle size and particle size distribution of the nanoemulsions prepared in groups A-E were measured by using a laser particle size analyzer (UK, Malvern Instruments) Nano ZS90 through dynamic light scattering. The droplet size of an emulsion is the mean diameter describing the cumulative measurements, measured in a sample cell at a fixed angle of 173°C. The particle size distribution is described by the particle size polydispersity index (Polymerdispersity index, PDI). The results are shown in Table 1.
[0046] The average particle diameter and PDI of table 1 nanoemulsion
[0047] index Group A Group B Group C Group D Group E Average particle size (nm) 25.84 23.16 20.15 27.40 29.56 PDI 0.13 0.12 0.11 0.14 0.15
[0048] PDI represents the particle size distribution of droplets in the system, and the smaller the value, the more uniform the particle size dispe...
Embodiment 3
[0049] Embodiment 3 has hair growth, scalp repair, preparation of the composition of moisturizing effect
[0050] Example 3 of the present invention has hair growth, scalp repair, and moisturizing compositions. %, diguanosine tetraphosphate 1.5%, Prolixir ICE 2%, nanoemulsion 6%, moisturizer 3%, thickener 0.5%, preservative 0.2%, and the balance is deionized water.
[0051] Preparation:
[0052] (1) Preparation of Trichosanthes extract: take fresh Trichosanthes whole plant, dry, pulverize, pass through a 15-mesh sieve, add 10 times the weight of the raw material with a volume fraction of 70% ethanol, and then add 1.2% cellulose of the total raw material Enzyme, leaching at 45°C for 2 hours, then reflux extraction at 90°C for 3 hours, filtering, concentrating and drying the filtrate under reduced pressure in vacuo to obtain Trichosanthes extract, in which the specific activity of cellulase is 5000U / g.
[0053] (2) Preparation of Polygala root extract: take fresh Polygala root...
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