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Quick-release oral care mouthwash fresh tablet and its preparation method and application

A technology for oral care and refreshing tablets, applied in the field of oral care, can solve the problems of low bioavailability, long action time, unsatisfactory sterilization effect, etc., and achieve the effects of shortening action time, convenient use and portability

Active Publication Date: 2019-04-26
北京瑞济善健康科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the bactericidal effect of existing products is usually unsatisfactory, the action time is long, and the bioavailability is not high

Method used

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  • Quick-release oral care mouthwash fresh tablet and its preparation method and application
  • Quick-release oral care mouthwash fresh tablet and its preparation method and application
  • Quick-release oral care mouthwash fresh tablet and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Take 0.01g of sodium fluoride and 3g of potassium nitrate and pass through a 100-mesh sieve for later use; 16g of citric acid, 37g of sodium bicarbonate, 3g of sodium benzoate, 10g of polyethylene glycol, 5g of povidone, 1.3g of essence, 23g of lactose, sodium saccharin 0.6g, menthol 0.5g, and silicon dioxide 0.3g are passed through an 80-mesh sieve for later use; the above powders are uniformly pressed into tablets. When pressing the tablet, the temperature is less than 18°C, and the air humidity is less than or equal to 40%.

Embodiment 2

[0046] Take 0.01g of sodium fluoride and 3g of potassium nitrate and pass through a 100-mesh sieve for later use; 17g of citric acid, 37g of sodium bicarbonate, 3g of sodium benzoate, 10g of polyethylene glycol, 5g of povidone, 3g of essence, 20g of lactose, and 0.6g of sodium saccharin g, 0.8 g of menthol, and 0.3 g of silicon dioxide are passed through an 80-mesh sieve for subsequent use; the above-mentioned powders are uniformly pressed into tablets. When pressing the tablet, the temperature is less than 18°C, and the air humidity is less than or equal to 40%.

Embodiment 3

[0048] Take 0.01g of sodium fluoride, 3g of potassium nitrate, 1g of sodium lauryl sulfoacetate through a 100-mesh sieve, and set aside; 3g of tartaric acid, 14g of citric acid, 37g of sodium bicarbonate, 3g of sodium benzoate, 10g of polyethylene glycol, and povidone 5g, essence 3g, lactose 19g, saccharin sodium 0.6g, menthol 0.8g, silicon dioxide 0.3g pass through 80-mesh sieve for later use; the above powder is uniformly pressed into tablets. When pressing the tablet, the temperature is less than 18°C, and the air humidity is less than or equal to 40%.

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Abstract

The invention discloses a quick-release oral care mouthwash refreshing tablet. The refreshing tablet contains 0.01-10wt% active ingredients, and the active ingredients are fluoride ion source, potassium ion source and sodium lauryl alcohol sulfoacetate. Any one or more. In addition, the preparation method and application of the aforementioned quick-release oral care mouthwash refreshing tablets are also disclosed. The present invention can better remove oral odor. At the same time, it can effectively help fluoride ions and / or potassium ions penetrate into the tooth surface, thereby improving its bioavailability against dentin sensitivity and greatly shortening its action time. In addition, sodium lauryl sulfoacetate has a synergistic effect with fluoride ion source and potassium ion source to prevent oral fungal infection, further improve the removal rate of harmful bacteria and the proportion of oral odor completely covered; The efficacy of the problem, such as the prevention and treatment of dental caries, anti-inflammation and sterilization, desensitization, hemostasis, fresh breath and other functions.

Description

technical field [0001] The invention belongs to the technical field of oral care, and relates to an oral care product, more specifically, to an immediate-release oral care mouthwash refreshing tablet and its preparation method and application. technical background [0002] The mouth is the beginning of the digestive tract and has many important functions. Oral care is an important part of basic care. First of all, healthy teeth can make people look good and feel better in daily life such as eating and talking. Secondly, good oral care for critically ill patients can avoid some complications, and the condition can be observed according to the health of the oral cavity. Third, disease in the oral cavity is a harbinger of disease in other parts of the body. For example, dry oral mucosa is the first signal of water and salt metabolism disorders; patients with anemia may have persistent oral ulcers and pharyngitis; patients with leukemia may have bleeding gums. Fourth, the en...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/21A61K8/19A61K8/44A61Q11/00A61P1/02A61P37/08A61P31/10
CPCA61K8/19A61K8/21A61K8/447A61Q11/00
Inventor 张青贺付俊昌
Owner 北京瑞济善健康科技有限公司
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