Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Personalized biomimetic dental implant and manufacturing method thereof

A technique for dental implants and implants, which is applied in the fields of dental implants, dentistry, and dental restorations. It can solve problems such as stress concentration and stress shielding, hinder the operation cycle, and incomplete cleaning, and achieve rapid and firm osseointegration and induction. Osteocyte generation, favorable effect on adhesion

Active Publication Date: 2019-07-02
STOMATOLOGICAL HOSPITAL TIANJIN MEDICAL UNIV
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are problems: most of the traditional titanium implants are fully dense, their elastic modulus is more than ten times that of natural bone, and their mechanical compatibility is poor. Occlusion, reducing the success rate and long-term life of the implant
The problem lies in: the surface coating of the substrate is uneven and the surface coating of the substrate with complex shapes cannot be processed; the processing temperature in the preparation is too high (10000 ° C), and the residual interfacial stress between the coating and the substrate during cooling causes the coating to loosen or peel off ; High temperature is easy to decompose HA to produce impurities such as amorphous HA, which affects the biological properties of the coating, etc.
Prolong the patient's treatment cycle, increase the patient's pain and treatment costs
[0017] 3) The lack of correct and effective guidance of the extraction socket for the direction of implant placement increases the complexity of the operation and the risk of damage to important structures such as nerves and blood vessels due to the deviation of the implant placement direction
It is not easy to obtain the ideal anatomical position, which affects the aesthetics and biomechanical compatibility of the later crown restoration
[0018] 4) The gingival papilla cannot be effectively preserved, which affects the aesthetic effect of implant denture restoration
[0019] 5) After tooth extraction, failure to repair immediately leads to the elongation and displacement of the opposing teeth and the oblique displacement of the adjacent teeth during the healing process of the extraction socket, which affects the later restoration effect
[0020] Fourth, most of the existing implants are imported, and a considerable part of the cost of implant restoration comes from the high cost of imported implant materials, resulting in high cost of implant restoration, which greatly increases the economic burden of patients and restricts the cost of implant restoration. The clinical further promotion of denture technology is difficult to benefit the majority of patients with missing teeth
In the process of promoting the development of domestic implants, the lack of strict implant quality control and the lack of diversified restoration options in the conventional assembly line production method have become bottlenecks restricting the development of domestic implants; making it difficult for domestic implants to obtain independent intellectual property rights Dominate the market
[0022] Fifth, the existing assembly line production methods of implants cannot meet the needs of individualized medical care and precision medicine in modern medicine, and are not conducive to the establishment of a harmonious doctor-patient relationship
[0025] The sand blasting acid etching and chemical processing methods used in the existing surface modification have a strong randomness in the processing process, and cannot achieve a uniform, regular, and repeatable surface treatment effect, and the surface coating has poor stability and is prone to dissolution, shedding problem
Due to the addition of reagents such as acid and alkali during the processing, the cleaning in the later stage is not thorough, and it is easy to produce different degrees of residues of toxic substances, which will affect the healing effect of the implant and even lead to implant failure.
Moreover, many reagents used in the processing technology are highly corrosive and have varying degrees of damage to the health of personnel, and discarded reagents will have adverse effects on environmental protection.
[0026] Comprehensive defects of the existing technology: the existing full-dense implants have the problems of poor mechanical compatibility and slow early osseointegration due to the mismatch between the elastic modulus and the bone tissue
Although the aim is to improve the biocompatibility of the implant surface by simulating the structure of natural bone tissue from two aspects of physical structure (rough surface morphology) and chemical composition (increasing calcium and phosphorus content) through implant surface treatment, but ultimately It is quite different from the structure of natural bone tissue, so it is impossible to obtain a three-dimensional porous network-like bionic bone tissue structure; in particular, it is impossible to match the patient's individual alveolar bone tissue structure and shape characteristics. An important defect is that it adopts assembly line mass production, the shape and size range are fixed, and it lacks a structure that is most bionic with natural bone tissue as the body structure of the implant, and finally obtains the ideal early rapid and firm osseointegration
This key defect, on the one hand, greatly hinders the development of immediate implant surgery with multiple advantages such as short operation period, low risk, rapid restoration of appearance and function, and avoidance of displacement of adjacent teeth and opposing teeth; on the other hand, it limits The research and development and promotion of domestic implants are difficult to meet the needs of individualized medicine in modern medicine, especially precision medicine
Moreover, there are also problems such as strong randomness in the processing process, inhomogeneous surface treatment results, poor stability, and difficulty in control. After the coating is prepared, it cannot be kept stable for a long time, and it is prone to problems such as dissolution, falling off, and pollution in the processing process.
In addition, due to the strong corrosiveness of the processing reagents, it has adverse effects on personnel health and environmental protection

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Personalized biomimetic dental implant and manufacturing method thereof
  • Personalized biomimetic dental implant and manufacturing method thereof
  • Personalized biomimetic dental implant and manufacturing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0071] In order to further understand the content, characteristics and effects of the present invention, the following examples are given, and detailed descriptions are as follows in conjunction with the accompanying drawings:

[0072] Such as Figure 1-7 As shown, a complete implant denture is mainly composed of three parts: crown 4 , abutment 3 , and implant body 1 . Wherein, the implant body 1 is the part where the implant denture is combined with the bone tissue, that is, the artificial tooth root, which is directly implanted into the patient's alveolar bone to play a role of fixation and support. The abutment 3 is located between the implant body 1 and the crown 4, and is connected to the implant body 1 apically, and connected to the crown 4 toward the coronal side, so as to connect the preceding and the following. The abutment 3 can be made separately or can be integrally made with the implant body 1 by 3D printing. Both the implant body 1 and the abutment 3 are not di...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to an individual biomimetic dental implant and a making method thereof, and the individual biomimetic dental implant includes an implant body imitating an original teeth root tissue structure of a missing tooth of a patient, a bionic artificial alveolar bone structure outer layer which is bonded with the outer surface of the implant body into one body, and biological protein molecule-bone morphogenetic protein (BMP) which is attached to the bionic artificial alveolar bone structure outer layer. The implant body and the bionic artificial alveolar bone structure outer layer are overall 3D-printed, and are similar to the original teeth root tissue structure and the alveolar bone tissue structure of the missing tooth of the patient, and the BMP-modified biological protein molecule promoting rapid bone formation is added, so that an ideal bionic artificial teeth root tissue structure is provided. The most important is to provide a good biological activity structure which is conducive to bone marrow stem cell and bone formation-related cell adhesion, proliferation and mineralization to finally play the osteogenic function, a bone formation promotion microenvironment is created, bone cell formation is induced, and early rapid and strong bone combination can be realized.

Description

technical field [0001] The invention belongs to a biomedical dental implant, in particular to an individualized bionic dental implant and a manufacturing method thereof. Background technique [0002] With the increase of traffic accidents and the acceleration of the aging process of society, the number of people with missing teeth is increasing year by year. With the improvement of people's living standards, people's requirements for the restoration of dentition defects and missing dentition are increasing. With the rapid development of implant technology, oral implants are increasingly widely used in the restoration of dentition defects and missing dentition to restore aesthetics and function. In the field of dental implants, pure titanium metal (or alloy) is widely used because of its good biocompatibility, mechanical properties and corrosion resistance. However, there are problems: most of the traditional titanium implants are fully dense, their elastic modulus is more ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61C8/00
CPCA61C8/0013A61C8/0043
Inventor 李莺李长义张旭宋云嘉刘亚林
Owner STOMATOLOGICAL HOSPITAL TIANJIN MEDICAL UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products