A method for preparing oxidized cellulose for hemostasis in the process of oxidative degumming of ramie

Abstract

The invention provides a method for preparing bleeding stopping oxidized celluloses in ramie oxidation degumming procedures. The method includes smashing raw ramie to obtain short fibers and soaking the short fibers to sufficiently moisten the short fibers and allow the short fibers to sufficiently swell; mixing the pretreated raw ramie short fibers and degumming solution with one another to obtain mixtures, heating the mixtures, then preserving heat, sufficiently removing colloid in the raw ramie by the aid of oxidability of specific oxidizing agents and simultaneously oxidizing celluloses with active hydroxyl to obtain oxidized celluloses with a large quantity of carboxyl; soaking oxidized and treated fibers by the aid of organic solvent aqueous solution and removing the unreacted oxidizing agents; separating the oxidized celluloses from water and carrying out drying treatment on the oxidized celluloses to ultimately obtain the powdery bleeding stopping oxidized celluloses. The method has the advantages that processes are simple, the original two working procedures are combined into a single working procedure, accordingly, the total reaction time can be shortened, medicines and the cost can be saved, and the efficiency can be greatly improved; the bleeding stopping oxidized celluloses which are products prepared by the aid of the method are high in bleeding stopping speed and bleeding stopping efficiency and can be widely applied to quickly stopping bleeding under conditions of war wound, trauma and the like, and stable effects can be realized.

Description

technical field [0001] The invention relates to a method for preparing oxidized cellulose for hemostasis in the oxidative degumming process of ramie, and belongs to the technical field of natural fiber preparation and application of oxidized cellulose for hemostasis in the textile field. Background technique [0002] In recent years, medical absorbable hemostatic materials have attracted great attention from the medical and industrial circles of various countries. With the improvement of performance requirements for hemostatic materials, the development of hemostatic materials with better hemostatic effect, green, environmental protection, degradable, non-toxic, no side effects, no stimulation It is imperative to develop a medical absorbable hemostatic material with high biocompatibility and good biocompatibility. At present, medical hemostatic materials mainly include fibrin glue, gelatin sponge, oxidized cellulose, microfibrous collagen, chitosan and calcium alginate fiber...

AI Technical Summary

Problems solved by technology

At present, the commercial product of oxidized cellulose clinically used as hemostatic gauze is "SURGICEL" of Johnson & Johnson, but the current form of the product is not conducive to combining with other products, and the production process is relatively complicated, the cost is high, and the price is high. Expensive, serious waste of oxidizing solution in the production process, it is urgent to develop better alternative products, exploring a better preparation process of medical hemostatic oxidized cellulose is an urgent proposition