Method for separating and purifying vitamin K2 in bacillus subtilis natto
A technology for separation and purification of Bacillus natto is applied in the field of bioengineering to achieve the effects of high biological activity, simple process operation and convenient industrial application.
Active Publication Date: 2017-05-10
HEFEI INSTITUTES OF PHYSICAL SCIENCE - CHINESE ACAD OF SCI
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The invention discloses a method for separating and purifying vitamin K2 in bacillus subtilis natto. The method comprises the following steps: acquiring vitamin K2 extract, acquiring a vitamin K2 column stock solution, acquiring a low-purity vitamin K2 concentrated solution, acquiring a high-purity vitamin K2 concentrated solution, acquiring high-purity vitamin K2, and acquiring vitamin K2 crystals. The method has the advantages that (1) an obtained vitamin K2 crystal product is high in purity, bioactivity and recovery rate; (2) a separation and purification process is easy to operate, mild in condition and high in treatment capability; (3) each organic solvent can be recycled for industrial application.
Application Domain
Quinone separation/purification
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Property | Measurement | Unit |
Molecular weight | 400.0 ~ 1000.0 | |
tensile | MPa | |
Particle size | Pa | |
strength | 10 |
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