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Glucosamine bone glue peptide calcium granules

A technology of granules and collagen peptides, which is applied in the field of medicine, can solve problems such as hard-to-reach and increase bone density, and achieve the effect of improving resistance, increasing bone density, and synergistic bone function

Active Publication Date: 2020-01-14
SHANDONG RUNDE BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, supplementing bone collagen or glucosamine alone is difficult to achieve the effect of increasing bone density and delaying aging

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] In parts by weight, take 45 parts of bone collagen peptide, 25 parts of glucosamine sulfate calcium salt, 13 parts of Antarctic krill oil, 7 parts of isomaltooligosaccharide, 4 parts of D-ribose, 4 parts of oat essence, 5 parts of Seaweed polysaccharide, 10 parts of shrimp powder, 7 parts of vitamin D3, 7 parts of fish oil, and appropriate amount of microcrystalline cellulose, magnesium stearate, and silicon dioxide were used to prepare glucosamine bone gel peptide calcium granules.

[0029]Wherein the preparation method of glucosamine sulfate calcium salt is as follows: get 1kg chitin and 1L 1-butyl-3-methylimidazole methyl sulfate, 3L mass concentration is 25% sulfuric acid and mix under the condition of 40 ℃ Stir to obtain a crude mother liquor, then use a diaphragm pump to continuously pump it into a microporous membrane filter to filter to obtain a fine mother liquor; mix the prepared fine mother liquor with 1-propylsulfanoyl-3-methylimidazolium bisulfate ionic liqu...

Embodiment 2

[0031] In parts by weight, take 40 parts of bone collagen peptide, 20 parts of glucosamine sulfate calcium salt, 10 parts of N-acetylglucosamine, 10 parts of Antarctic krill oil, 5 parts of isomaltooligosaccharide, 3 parts of D-ribose , 2 parts of oat essence, 3 parts of seaweed polysaccharide, 8 parts of shrimp powder, 5 parts of vitamin D3, 5 parts of fish oil, and appropriate amount of microcrystalline cellulose, magnesium stearate, and silicon dioxide to prepare glucosamine bone glue peptide calcium granules.

[0032] Wherein the preparation method of glucosamine sulfate calcium salt is as follows: get 1kg chitin and 2L 1-butyl-3-methylimidazole methyl sulfate, 4L mass concentration is 20% sulfuric acid and mix and stir under the condition of 35 ℃ Obtain thick mother liquor, then use diaphragm pump to continuously pump into microporous membrane filter and filter to obtain fine mother liquor; The degradation solution was prepared by mixing and incubating at 80°C for 3 hours...

Embodiment 3

[0034] In parts by weight, take 50 parts of bone collagen peptide, 30 parts of glucosamine sulfate calcium salt, 15 parts of Antarctic krill oil, 10 parts of isomaltooligosaccharide, 6 parts of D-ribose, 5 parts of oat essence, 7 parts of Seaweed polysaccharide, 13 parts of shrimp skin powder, 9 parts of vitamin D3, 9 parts of fish oil, and appropriate amount of microcrystalline cellulose, magnesium stearate, and silicon dioxide were used to prepare glucosamine bone gel peptide calcium granules.

[0035] Wherein the preparation method of glucosamine sulfate calcium salt is as follows: get 1kg chitin and 1L 1-butyl-3-methylimidazole methyl sulfate, 2L mass concentration is 30% sulfuric acid and mix under the condition of 45 ℃ Stir to obtain a crude mother liquor, then use a diaphragm pump to continuously pump it into a microporous membrane filter to filter to obtain a fine mother liquor; mix the prepared fine mother liquor with 1-propylsulfanoyl-3-methylimidazolium bisulfate ion...

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PUM

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Abstract

The invention belongs to the medical field and discloses glucosamine bone glue peptide calcium granules. The glucosamine bone glue peptide calcium granules comprises bone collagen peptide, glucosamine, euphausia superb oil, isomaltooligosaccharide, D-ribose, oat essence, algal polysaccharides, dried small shrimp meal, vitamin D3, fish oil and pharmaceutical adjutants. The bone collagen peptide, the glucosamine, the dried small shrimp meal and the euphausia superb oil in the glucosamine bone glue peptide calcium granules can be absorbed by a human body easily, are jointly used for increasing bone density and recovering bone functions, have a synergistic effect and can enhance resistance, maintain beauty and care skin.

Description

technical field [0001] The invention relates to the field of medicine, in particular to an aminoglucose bone glue peptide calcium granule. Background technique [0002] Bone mineral density is the main indicator of bone strength, an important sign of bone quality, and an important basis for reflecting the degree of osteoporosis and predicting the risk of fracture. People's bone density reaches its peak at about 30 years old, and then it will decline year by year due to bone loss with age. According to reports, regardless of men and women, after the age of 60, bone loss generally reaches 20% to 30% of the peak value, and the maximum can reach 40%. With the growth of age, compared with young people under the age of 30 under the same nutritional conditions, middle-aged and elderly people still inevitably suffer from a large amount of bone loss, decreased bone density, decreased bone strength, and gradually become loose and easy to break. Therefore, middle-aged and elderly peo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/39A61K9/16A61K47/38A61P19/10C07H1/00C07H5/06A61K31/593A61K31/7004A61K31/7008A61K31/702A61K31/715A61K35/60A61K35/612
CPCA61K9/1652A61K31/593A61K31/7004A61K31/7008A61K31/702A61K31/715A61K35/60A61K35/612A61K38/39A61P19/10C07H1/00C07H5/06A61K2300/00
Inventor 卢健行马善丽吴祥舟赵鹏卢建智
Owner SHANDONG RUNDE BIOTECH CO LTD
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