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Nutritional supplement suitable for perimenopausal women

A vitamin and composition technology, applied in the field of vitamin nutrition composition, can solve the problems of many kinds of ingredients, increase the risk of atherosclerosis, and low ingredient content, achieve good process feasibility, protect the cardiovascular system, and prevent menopausal depression Effect

Inactive Publication Date: 2020-02-14
SHENZHEN AUSA PHARMA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This risk-increasing effect mainly comes from three aspects: first, abdominal fat and myocardial fat increase in perimenopausal women, both of which are risk factors for cardiac adverse events; second, fluctuations in estrogen and progesterone levels in perimenopausal women may Lead to abnormal regulation mechanism of renin secretion, causing blood pressure to rise; in addition, plasma cholesterol, triglyceride, and homocysteine ​​levels may increase after menopause, increasing the risk of atherosclerosis
[0006] Menopausal women have become an increasingly large group. To meet the specific physiological and nutritional needs of this group, there are not many vitamin health products on the market at present, and there are many types of ingredients, but the content of each ingredient is low. Urgent improvement is needed to meet the needs of the era of precision nutrition

Method used

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  • Nutritional supplement suitable for perimenopausal women
  • Nutritional supplement suitable for perimenopausal women
  • Nutritional supplement suitable for perimenopausal women

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1: the tablet preparation (1000 pieces quantity) of vitamin composition of the present invention

[0030] formula:

[0031]

[0032] Preparation method: take povidone K30 and prepare an adhesive with 50% ethanol solution, then add vitamin E and vitamin D into the adhesive, stir evenly, and set aside. Extra Vitamin B 12 , folic acid, sucralose and pregelatinized starch are mixed and sieved, then milk essence, carboxymethyl starch sodium and dextrin are added to mix, and the prepared soft material containing vitamin E and vitamin D binder is added, and the 24-mesh sieve is used Granulate, dry at 55°C for 2 hours, sieve through a 24-mesh sieve, add magnesium stearate to mix, and press into tablets. The coating premix is ​​formulated into a solution, and the plain tablet is coated to obtain the health food tablet of the present invention.

Embodiment 2

[0033] Embodiment 2: the soft capsule preparation (1000 grain amount) of vitamin composition of the present invention

[0034] formula:

[0035]

[0036] Preparation method: add beeswax to soybean oil, heat at 50°C to dissolve the beeswax, place it at room temperature, take folic acid, vitamin D, vitamin E, and vitamin B 12 Add soybean oil to make a suspension and set aside. In addition, gelatin, purified water, caramel color, and parabens are prepared into a glue solution, and the prepared suspension is pressed into pills by a pill press to make soft capsules. After shaping, pill washing and drying, it is prepared Obtain the soft capsule of health food of the present invention.

[0037] Take the health food prepared in this example, and carry out animal function test and safety toxicology evaluation test according to the evaluation method of "Technical Specification for Health Food Inspection and Evaluation" issued by the Ministry of Health.

[0038] Female castrated rats...

Embodiment 3

[0080] Embodiment 3: preparation of vitamin composition hard capsules of the present invention (1000 grains amount)

[0081] formula:

[0082]

[0083]

[0084] Preparation method: mix folic acid with 20% microcrystalline cellulose, sieve, then add vitamin E, vitamin D, and vitamin B 12 Mix the obtained raw material mixture with the remaining amount of microcrystalline cellulose in equal increments, then add lactose and magnesium stearate to mix, then use a full-automatic capsule filling machine to fill, and after polishing, obtain the capsules of the present invention. Hard capsules of the health food mentioned above.

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Abstract

The invention provides a composite vitamin health-care food composed of vitamin E, vitamin D, folic acid, vitamin B12 and health-care food acceptable auxiliary materials, aiming at the health risk ofperimenopausal women. The nutritional supplement accurately supplements vitamin E, vitamin D, folic acid and vitamin B12 so as to improve estrogen disorder, prevent osteoporosis and climacteric depression and protect the cardiovascular system. The nutritional supplement is not only a significant improvement and upgrade of existing compound vitamin products, but also an example for implementing accurate nutrition on physiological characteristics of perimenopausal women, and has process feasibility and good market prospects.

Description

technical field [0001] The invention relates to a vitamin nutritional composition, more precisely, the invention relates to a health food or nutritional supplement designed for perimenopausal women and capable of preventing osteoporosis and menopausal depression. Background technique [0002] Perimenopause is the period when women transition from reproductive to non-reproductive, also known as menopause, which usually occurs between the ages of 45 and 55. During this stage, women's ovarian function gradually declines, and estrogen secretion decreases, which can easily lead to a series of physiological and psychological changes, which will affect women's health and quality of life. Among them, osteoporosis, menopausal depression and increased risk of cardiovascular disease are more common hidden dangers. [0003] The incidence of osteoporosis in women over 65 years old in the United States is 26%, and the incidence of osteoporosis in women over 50 years old in my country is ...

Claims

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Application Information

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IPC IPC(8): A23L33/15A23L33/155
CPCA23L33/15A23L33/155A23V2002/00A23V2200/30A23V2250/712A23V2250/71A23V2250/706A23V2250/7056
Inventor 张磊姜城子白洁徐希平王玉
Owner SHENZHEN AUSA PHARMA
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