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Infant formula milk powder containing gastrointestinal regulation peptide and preparation method thereof

A technology for infant formula and milk powder, which is applied in the direction of milk preparations, dairy products, applications, etc., and can solve problems such as bitter taste, low lactose content, and infant malnutrition

Pending Publication Date: 2021-01-05
THE WEST CHINA SECOND UNIV HOSPITAL OF SICHUAN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The 0-6 month infant formula milk powder disclosed in this patent document to prevent lactose intolerance and protein allergy, although many additional nutrients are added, actually still belongs to the category of hydrolyzed protein milk powder, and the depth of hydrolysis is not complete
Its scope of application is still children with clinically confirmed milk protein allergy, the applicable population is still a very small number of clinically ill patients, and it cannot be used for the prevention of milk allergy in a wide range of people
Moreover, because the main ingredient of milk powder is hydrolyzed whey protein, it also has the disadvantage of bitter taste, which is difficult for infants to accept.
In addition, this milk powder has very low lactose content, which is an important nutrient for infant development. Unless it is a baby with severe lactose intolerance, it is not recommended for babies to use low-lactose milk powder for a long time in clinical practice, which will cause malnutrition and developmental impairment of the baby. limit
Therefore, the 0-6 month infant formula milk powder disclosed in this patent document to prevent lactose intolerance and protein allergy is still not suitable for the prevention of cow's milk protein allergy in a wide range of infant populations.

Method used

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  • Infant formula milk powder containing gastrointestinal regulation peptide and preparation method thereof
  • Infant formula milk powder containing gastrointestinal regulation peptide and preparation method thereof
  • Infant formula milk powder containing gastrointestinal regulation peptide and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054]An infant formula containing gastrointestinal regulatory peptides, including the following components in weight ratio:

[0055]Infant formula milk powder 100g

[0056]Motilin 193.93ng

[0057]14 peptide somatostatin 310.29ng;

[0058]The chemical formula of motilin is C120H188N34O35S, the molecular weight is 2699.05, and the concentration is 250ng / L;

[0059]The chemical formula of the 14 peptide somatostatin is C76H104N18O19S2, The molecular weight is 1638, and the concentration is 400ng / L.

[0060]Somatostatin SST can significantly reduce the allergenicity of ordinary milk powder, significantly reduce the allergic digestive tract injury induced by milk protein, and reduce the risk of milk allergy; Motilin MTL can significantly improve the gastrointestinal tolerance of ordinary milk powder , And can well improve baby’s appetite and gastrointestinal motility; the simultaneous addition of somatostatin SST and motilin MTL has the effect of offsetting mutual side effects and synergistically regula...

Embodiment 2

[0062]An infant formula containing gastrointestinal regulatory peptides, including the following components in weight ratio:

[0063]Infant formula milk powder 100g

[0064]Motilin 193.93ng

[0065]14 peptide somatostatin 310.29ng;

[0066]The chemical formula of motilin is C120H188N34O35S, the molecular weight is 2699.05, and the concentration is 250ng / L;

[0067]The chemical formula of the 14 peptide somatostatin is C76H104N18O19S2, The molecular weight is 1638, and the concentration is 400ng / L.

[0068]The weight ratio components of the infant formula milk powder are 95.16 g of whole milk powder, 2.80 g of linoleic acid, 375 g of α-linoleic acid, 396 ug of vitamin A, 7.00 ug of vitamin D, and 6.00 mg of vitamin E per 100 g. Vitamin K134.00ug, vitamin B1 380.00ug, vitamin B2 700ug, vitamin B6 280ug, vitamin B12 0.9ug, niacin 3500ug, folic acid 70.0ug, pantothenic acid 2600ug, vitamin C 70mg, biotin 11.4ug, sodium 150mg, potassium 531mg, copper 290ug, magnesium 48mg, iron 5.6mg, zinc 3.30mg, mangane...

Embodiment 3

[0072]A method for preparing infant formula milk powder containing gastrointestinal regulatory peptides includes the following steps:

[0073]a. Preparation of raw milk: raw milk is purified and filtered. Use skim milk powder, whey protein powder and mixed vegetable oil to adjust the ingredients to a standardized content. After mixing, filter again and homogenize, pre-cook at 80°C for 20 seconds to sterilize, and cool to 4℃ standby;

[0074]b. Premixes with nutritional fortification ingredients: including water-soluble vitamin premixes, fat-soluble vitamin premixes, mineral and trace element premixes, unsaturated fatty acid premixes, nucleotide premixtures and amino acid premixtures ;

[0075]c. Configure active gastrointestinal regulatory peptide premix: each active gastrointestinal regulatory peptide premix includes 25ng of motilin and 40ng of 14 peptide somatostatin;

[0076]d. Mixing and homogenization: mix the emulsion and pre-mixed ingredients in the following proportions, 100ml of standa...

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Abstract

The invention discloses infant formula milk powder containing gastrointestinal regulation peptide, and belongs to the technical field of preparation of formula milk powder. The infant formula milk powder is characterized by comprising the following components by weight: 100g of infant formula cow milk powder, 193.93 ng of motilin and 310.29 ng of 14 peptide somatostatin; the concentration of the motilin is 250 ng / L; and the concentration of the 14 peptide somatostatin is 400 ng / L. The infant formula milk powder can well simulate breast milk components, significantly reduce allergenicity of cowmilk, significantly improve gastrointestinal tract tolerance of common infant formula milk powder and improve infant appetite, has no bitter and astringent taste, and is simple in preparation process; and the milk powder can be used for generally preventing food allergy and food intolerance of vast infant crowds, and has the effects of reducing allergenicity, improving gastrointestinal tract tolerance of the cow milk and improving appetite of infants.

Description

Technical field[0001]The invention relates to the technical field of formula milk powder preparation, in particular to an infant formula milk powder containing gastrointestinal regulatory peptides and a preparation method thereof.Background technique[0002]The existing baby milk powder preparations on the market are divided into three categories: ordinary whole protein milk powder, different levels of hydrolyzed protein milk powder and bovine colostrum milk powder containing maternally transmitted antibodies.[0003]Ordinary whole protein milk powder: This type of whole protein structure has the highest risk of causing allergies and has relatively poor gastrointestinal tolerance. Not suitable for infants with milk allergy.[0004]Different levels of hydrolyzed protein milk powder: including partially hydrolyzed protein milk powder, deep hydrolyzed protein milk powder and amino acid milk powder, this kind of milk powder can only be used clinically to treat babies who have developed milk a...

Claims

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Application Information

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IPC IPC(8): A23C9/16A23C9/152A23C9/158
CPCA23C9/16A23C9/152A23C9/1528A23C9/158A23C9/1522A23C9/1526Y02P60/87
Inventor 谢咏梅
Owner THE WEST CHINA SECOND UNIV HOSPITAL OF SICHUAN
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