Three-dimensional porous tissue engineering stand material and preparation thereof

A tissue engineering scaffold and three-dimensional porous technology, applied in the field of biomedical materials-tissue engineering scaffold materials, can solve the problems of natural polymers lacking spatial structure and mechanical strength, and unsatisfactory biodegradability, etc., to achieve good biological activity and degradation Sexuality, low cost, and wide-ranging effects
CN1613514AInactive Publication Date: 2005-05-11XIAMEN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
XIAMEN UNIV
Publication Date
2005-05-11
Estimated Expiration
Not applicable · inactive patent

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Abstract

A 3D porous scaffold material for tissue engineering to induce the generation of bone tissue is prepared from chitosan, gelatin, GPSM and calcium nitrate through sol-gel process, chemical treating and freeze drying. Its advantages are high bioactivity and degradability, proper porosity and pore diameter, and controllable properties.
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Description

technical field

[0001] The invention relates to a biomedical material with good biological activity and degradability-tissue engineering scaffold material. Background technique

[0002] Since the 19th century, bone grafting has been committed to repairing large-scale bone defects caused by trauma, tumors, and infections to restore limb function. But there are many problems with this method, such as immune rejection and shortage of donor tissues and organs. An ideal strategy is to artificially cultivate tissues and organs, and then put forward the concept of tissue engineering, whose goal is to use the composite culture of cells and biological scaffold materials to regenerate bone tissue and achieve the purpose of repair. Among them, on the one hand, the scaffold material serves as a carrier of signal molecules or cells to deliver them to the defect site, and on the other hand, it provides a scaffold for new bone growth. At present, a variety of materials have been used as ...

Claims

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