Probiotics-containing female hygienic product as well as preparation method and application thereof

A hygienic product and probiotic technology, which is applied in the field of feminine hygiene products and its preparation, to achieve the effects of prolonging the shelf life, good antibacterial effect, and strong acid resistance

Inactive Publication Date: 2011-07-13
BIOGROWING CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] One of the technical problems to be solved by the present invention is to provide a probiotic with a high survival rate under humid conditions and a strong adhesion ability t

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0039] Example 1:

[0040] Production of sanitary napkins containing probiotics

[0041] 1. Preparation of culture medium for Lactobacillus rhamnosus and Lactobacillus casei: glucose 1-2%, beef extract 0.5-1%, peptone 0.5-1%, yeast extract 0.5-1%, diammonium citrate 0.1-0.5% , Anhydrous sodium acetate 0.1~0.5%, dipotassium hydrogen phosphate 0.05~0.2%, magnesium sulfate 0.05~0.2%, manganese sulfate 0.01~0.3%, Tween 0.01~0.1% and the balance distilled water, pH 6~7 medium Expand the culture and collect the bacterial sludge.

[0042] According to the ratio of excipients: bacterial mud = 1.0: 0.1-100, the bacterial mud and excipients are thoroughly mixed. The excipients are lactose 0.5-10%, trehalose 0.5-10%, glycerol 0.1-5%, maltodextrin 0.5-10%, 0.5-10% triglyceride, in the weight ratio of -80~-40 Pre-freezing at ℃ for 3-10 hours, freeze-drying at -40~-60℃, 0.1-1.0Pa for 12-24 hours to obtain Lactobacillus rhamnosus powder and Lactobacillus casei powder.

[0043] 2. Weigh Lactobacil...

Example Embodiment

[0045] Example 2:

[0046] Production of tampons containing probiotics

[0047] 1. Making Lactobacillus gasseri powder and Lactobacillus fermentum powder, the specific method is the same as step 1 in Example 1;

[0048] 2. Weigh Lactobacillus gasseri powder and Lactobacillus fermentum powder at a mass ratio of 1.0:0.1-10, mix them evenly and dissolve them in sterile water to obtain a bacterial suspension. Total number of viable bacteria in liquid 1×10 9 ~10 12 cfu / ml.

[0049] 3. Soak the tampon absorbent core (that is, the surface layer between the surface layer and the absorbent layer) in the bacterial suspension. After the bacterial suspension is completely and evenly immersed in the surface layer, under low temperature conditions (less than 45°C) The surface layer is dried to obtain the finished product.

Example Embodiment

[0050] Example 3:

[0051] Production of toilet paper containing probiotics

[0052] 1. Making Lactobacillus gasseri powder and Lactobacillus fermentum powder, the specific method is the same as step 1 in Example 1;

[0053] 2. Weigh Lactobacillus gasseri powder and Lactobacillus fermentum powder at a mass ratio of 1.0:0.1-10, mix them evenly and dissolve them in sterile water to obtain a bacterial suspension. Total number of viable bacteria in liquid 1×10 9 ~10 12 cfu / ml.

[0054] 3. Spray the above bacterial suspension with a spray machine on the surface of the toilet paper that is running (drying temperature is lower than 45°C). At this time, the bacterial liquid adheres to the surface of the toilet paper and is dried at low temperature or air-conditioned. Then use ordinary toilet paper to cut and package.

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Abstract

The invention discloses a probiotics-containing female hygienic product, comprising a carrier; a probiotics composition is attached onto the carrier and comprises lactobacillus and an excipient, wherein the excipient is combined with polysaccharide or lipid substances; and the viable count of a unit product is 107-1012CFU. The invention further discloses a preparation method of the probiotics-containing female hygienic product. The active probiotics or variants thereof in the invention can adhere to a female vagina and breed in a fixed way, and the selected bacterial strains belong to single strain or combination of strains of lactobacillus casei, lactobacillus rhamnosus, lactobacillus gasseri, lactobacillus fermentium and bacteroides fragilis, and can be used for treating or preventing bacterial vaginosis, candidal vaginitis, HIV (Human Immunodeficiency Virus) infectious diseases, chlamydia infectious diseases, infectious diseases endangering a fetus of a pregnant woman, premature-birth infectious diseases, and urinary tract infectious diseases. The preparation method provided by the invention is simple and economic and is beneficial to product storage.

Description

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Claims

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Application Information

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Owner BIOGROWING CO LTD
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