Magnesium alloy sheet-reinforced absorbable intrabony fixing composite material and preparation method thereof

Abstract

The invention discloses a magnesium alloy sheet (strip)-reinforced absorbable intrabony fixing composite material and a preparation method thereof. The preparation method comprises the following steps of: dispersing and arranging magnesium alloy sheets or thin strips which are subjected to micro arc oxidation in an absorbable high molecular material serving as a substrate in an oriented way to enhance the mechanical performance of the absorbable composite material; mixing degradable polymer substrates such as poly(lactic acid) and the like with a magnesium alloy sheets or thin strip reinforced phase; manufacturing a bar and a plate by performing die pressing or extruding at the temperature of 80-235 DEG C under the pressure of 0.5-40 MPa; and performing subsequent machining to obtain various intrabony fixing products. The method has the characteristic of easiness in operating process conditions; a product has excellent mechanical performance, high biocompatibility, and safe, stable and controllable product degradation, is suitable for intrabony fixing products of various shapes, and has a wide market prospect; and pain of a patient caused by the need of secondary surgery or advanced failure of an orthopaedic fixing product.

Description

technical field [0001] The invention relates to an orthopedic internal fixation material in medical equipment, belongs to the field of biomedical equipment, and is particularly suitable for the fields of orthopedic trauma surgery, bone defect repair surgery, and medical equipment for plastic surgery. Specifically, it is a magnesium alloy sheet or strip reinforced resorbable bone internal fixation composite material, which is an bone internal fixation composite material formed by compounding a resorbable magnesium alloy sheet or thin strip reinforcement phase with a polylactic acid matrix. Background technique [0002] Internal bone fixation is a routine method in orthopedic trauma surgery, bone defect repair surgery, and plastic surgery. Currently, internal fixation plates and screws are most commonly made of pure titanium or titanium alloy, which have stable fixation effects and superior biocompatibility. It provides a good internal environment for bone tissue healing, but ...

AI Technical Summary

Problems solved by technology

[0002] Internal bone fixation is a routine method in orthopedic trauma surgery, bone defect repair surgery, and plastic surgery. Currently, internal fixation plates and screws are most commonly made of pure titanium or titanium alloy, which have stable fixation effects and superior biocompatibility. It provides a good internal environment for bone tissue healing, but it also has the following problems: (1) The elastic modulus of titanium metal is 8 times that of cortical bone, and it has a stress shielding effect on normal bone tissue, which is easy to cause osteoporosis and relapse Fracture; (2) It cannot be degraded and absorbed. If it is used for a long time, it will block X-rays and affect imaging examinations and chemotherapy for cancer patients.

[0007] Therefore, in order to solve the above-mentioned existing problems, a kind of bone internal fixation composite material prepared by the present invention is composed of absorbable magnesium alloy flakes or strips as a reinforcing phase and polylactic acid as a matrix. Materials and biodegradable magnesium alloys have their respective advantages, but at the same time they can overcome their respective shortcomings. They have good application prospects in orthopedic trauma surgery, bone defect repair surgery, plastic surgery, especially in internal fixation of high-stress fractures. , but so far there have been no relevant research reports at home and abroad