Method for preparing compound pseudo-ginseng film coated tablet

Abstract

The invention discloses a method for preparing a compound pseudo-ginseng film coated tablet. The method comprises steps of grinding, granulating, tabletting, coating and the like. According to the preparation method, the number of bacteria, mould, escherichia coli and other pathogenic bacteria in a product can be greatly reduced, moisture in medicinal materials can be reduced, and the medicinal materials can be easily ground; the content of ginsenoside in each compound pseudo-ginseng film coated tablet can be increased, and the product quality and acting effect on a focus can be improved; the tablet can be easily disintegrated in stomach and intestines, so that the releasing speed of the medicinal materials can be increased, the tablet can be absorbed in time to reach the level of plasma concentration after a patient takes the tablet, and the curative effect can be improved; coating materials can be reduced, and cost can be reduced; the tablet can be directionally absorbed by a human body; the labor production rate can be improved, and the labor intensity of workers can be reduced; and the preparation process can be simplified, potential consumption of raw materials can be eliminated, and industrialization can be easily realized.

Description

technical field [0001] The invention belongs to the technical field of Chinese patent medicines, and relates to a preparation method of Chinese patent medicines, in particular to a preparation method of compound notoginseng film-coated tablets. Background technique [0002] Compound Panax notoginseng film-coated tablets have the effects of removing blood stasis, stopping bleeding, reducing swelling and relieving pain, and are mainly used for bruises, blood stasis, swelling and pain, traumatic bleeding, contusions, sprains, and femoral trauma. However, the existing preparation method of compound notoginseng film-coated tablets needs to prepare dry cream powder and notoginseng fine powder respectively first, then add appropriate amount of auxiliary materials to the dry cream powder and notoginseng fine powder to mix and evenly granulate, and finally add volatile oil ethanol Solution or volatile oil cyclodextrin inclusion compound and appropriate amount of auxiliary materials a...

AI Technical Summary

Problems solved by technology

However, the existing preparation method of compound notoginseng film-coated tablets needs to prepare dry cream powder and notoginseng fine powder respectively first, then add appropriate amount of auxiliary materials to the dry cream powder and notoginseng fine powder to mix and evenly granulate, and finally add volatile oil ethanol Solution or volatile oil cyclodextrin inclusion compound and appropriate amount of auxiliary materials are mixed, tableted, coated, etc. and the dry cream powder also includes 1 / 2 of the prescription amount, and the preparation of dry cream powder itself is a very complicated process. The process requires crushing various raw materials first, then cooking, spray drying, etc.

It can be seen that the preparation process of the existing compound notoginseng film-coated tablets is complex, which brings the following problems: (1) the bacteria, molds and pathogenic bacteria used in the original medicine often exceed the standard limit. (2) Due to high-temperature drying in several processes, the content of active ingredients often cannot meet the minimum requirements of the standard; (3) Sugar-coated tablets are prone to moisture absorption, discoloration and splitting; (4) The disintegration time limit of sugar-coated tablets often exceeds the limit; ( 5) Particles made of mint and Nepeta volatile oil are difficult to mix with other medicinal materials, and are prone to volatile loss; (6) Long production time, large material loss, high energy consumption, and high production cost

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