Application of lactobacillus helveticus NS-8 fermented liquor

A fermented liquid and Lactobacillus technology, which can be used in fermentation, cosmetic preparations, skin care preparations, etc., can solve the problems of high cost and poor stability, and achieve the effect of wide application, low cost and good oxidation resistance

Inactive Publication Date: 2015-04-29
王沥 +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, common anti-melanin production and antioxidants, such as kojic acid and vitamin C, have problems in practical application such as poor stab

Method used

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  • Application of lactobacillus helveticus NS-8 fermented liquor
  • Application of lactobacillus helveticus NS-8 fermented liquor
  • Application of lactobacillus helveticus NS-8 fermented liquor

Examples

Experimental program
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Effect test

preparation example Construction

[0023] The preparation of Lactobacillus NS-8 fermentation broth is as follows: Inoculate Lactobacillus helveticus NS-8 into MRS medium for 12-24 hours of fermentation, and the fermentation product is centrifuged and filtered through a microporous membrane to obtain sterile NS-8 fermentation broth.

[0024] Through the detection of melanoma cell tyrosinase activity, melanin content and spectrophotometer, the anti-melanin production and anti-oxidation properties of NS-8 fermentation broth were determined. The results show that the lactic acid bacteria NS-8 fermentation liquid obtained by the present invention can effectively inhibit the activity of tyrosinase, reduce the production of melanin in cells, and can effectively remove oxygen free radicals. The NS-8 fermented liquid obtained by the present invention can be used as a natural and highly active whitening ingredient in the development of skin care products and cosmetics.

Embodiment 1

[0025] Example 1 .Using Lactobacillus helveticus NS-8 fermentation broth as an ingredient for the preparation of Lactobacillus body lotion

[0026] Formula by weight percentage:

[0027] Element w / % Lactobacillus NS-8 fermentation broth 10 Deionized water 60 rose flower water 3 glycerin 10 Tween 80 2 Propylene Glycol 2 Iodopropynyl butylcarbamate 5 Glyceryl caprylate 5 Hydrolyzed Collagen 1 Sodium hyaluronate 1 rose essential oil 1

[0028] The product contains the fermentation product of Lactobacillus NS-8, which can effectively regulate the function of the skin, and is combined with a variety of natural active ingredients, such as hyaluronic acid, collagen, rose extract, etc., with a mild fermented smell, you can experience the symbiosis with nature a feeling of. Do not use any synthetic surfactants, synthetic fragrances, artificial colors, mineral oil, ethanol, preservatives, phenoxyetha...

Embodiment 2

[0029] Example 2 . Lactobacillus helveticus NS-8 fermentation broth is used as an ingredient to prepare Lactobacillus soap (daily chemical products)

[0030] Formula by weight percentage:

[0031] Element w / g (total weight 80g) Lactobacillus NS-8 fermentation broth 5 Deionized water 30 Soap base 30 Sodium citrate 10 olive oil 2 Zeolite 2 Chamomile Extract 0.5 Eucalyptus essential oil 0.5

[0032] Natural soap with Lactobacillus helveticus NS-8 fermentation liquid as the formula ingredient, combined with zeolite and other cleaning ingredients, does not use antioxidants such as ethylenediaminetetraacetic acid salts that irritate the skin, and has a gentle formula that moisturizes the skin.

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Abstract

The invention discloses a novel application of lactobacillus helveticus NS-8 fermented liquor. The lactobacillus helveticus NS-8 fermented liquor can serve as a raw material to be used for preparing cosmetics or daily chemical products with anti-oxidation and anti-melanogenesis effects. Lactobacillus helveticus NS-8 is separated from a natural fermented product in Inner Mongolia prairie of China and has good activity of probiotics. The lactobacillus helveticus NS-8 is conventionally fermented for 12-24 hours, centrifuged and filtered to separate out the aseptic fermented liquor. Intracellular and extracellular detection proves that the fermented liquor has activity of tyrosinase in a mode of inhibiting melanogenesis and can effectively reduce generation of melanin in cells. In addition, a spectrophotometer detects that the fermented liquor can remarkably remove formation of oxygen free radicals and is good in oxidation resistance. Therefore, the obtained lactobacillus helveticus NS-8 fermented liquor can serve as a natural effective component to be applied to products such as the cosmetics and the daily chemical products.

Description

technical field [0001] The invention belongs to the fields of biomedicine and food, and in particular relates to a new application of Lactobacillus helveticus NS-8 fermentation liquid. Background technique [0002] Fair skin has always been admired by Asian women. On the one hand, the formation of human melanin is the skin's own protection mechanism against ultraviolet rays, and on the other hand, the disorder of melanin metabolism will cause excessive accumulation of skin melanin, leading to various pigmentation symptoms such as chloasma, age spots, and freckles. even skin cancer. In the biosynthetic pathway of melanin, tyrosinase is the most important rate-limiting enzyme. Studies have shown that the structure and activity of tyrosinase are mainly affected by genes, hormones, cytokines and ultraviolet rays. At present, a variety of whitening ingredients from chemical synthesis or natural products have been applied to skin care products or cosmetics, such as kojic acid...

Claims

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Application Information

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IPC IPC(8): A61K8/99A61Q19/08A61Q19/00A61Q19/10A61Q1/06C12P1/04C12R1/225
Inventor 王沥戎晶晶
Owner 王沥
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