Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Au@Cu2-deltaX nanoscale crystal and preparation method and application thereof

A nanocrystal, aucu2- technology, applied in nanotechnology, nanotechnology, nanotechnology for materials and surface science, etc., can solve problems such as low absorption of sulfides, reduced photothermal conversion efficiency, etc., and achieve mild reaction conditions. Effect

Active Publication Date: 2016-01-27
BEIJING INSTITUTE OF TECHNOLOGYGY
View PDF6 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the current photothermal conversion materials have defects in photothermal conversion efficiency and biocompatibility: first, noble metals are heavy metals, which have certain biological toxicity, and their surfaces need to be modified or modified before they can be used in cancer photothermal therapy , such as coating SiO on the surface of Au nanorods 2 etc.; secondly, the absorption of copper sulfide in the near-infrared is low, which reduces the overall photothermal conversion efficiency
Although it has been reported to combine different copper sulfides and noble metals such as Au to form heterojunction structures, these heterojunction structures have not completely solved the two defects of photothermal conversion materials at present.
[0005] At present, in the photothermal reagent synthesis, there is still no way to combine Au and Cu 2-δ X, X=S, Se or Te, forming a uniform and controllable core-shell nanocrystal structure, forming a photothermal with high absorption coefficient in the near-infrared lesion window, high photothermal conversion efficiency, adjustable absorption band, and low toxicity Reagent

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Au@Cu2-deltaX nanoscale crystal and preparation method and application thereof
  • Au@Cu2-deltaX nanoscale crystal and preparation method and application thereof
  • Au@Cu2-deltaX nanoscale crystal and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] 1. Preparation of granular AuCdS nanocrystals

[0064] (1) Stir 0.72mL of oleic acid, 1mL of 1mol / L sodium hydroxide solution, 4mL of acetonitrile and 4mL of water at room temperature, then add chloroauric acid (HAuCl 4 4H 2 (2) 20 mg, stirred to form a uniform transparent microemulsion, added 80 μL of 0.1mol / L ascorbic acid solution and 13 mL of cyclohexane, and continued to stir for 6 h, left to stand, after layering, take the organic layer liquid; add ethanol to the organic layer liquid 39mL, and centrifuged at 2000rpm for 7min to obtain 4nm granular Au nanocrystals;

[0065] (2) Disperse the granular Au nanocrystals in 20mL of toluene to obtain the granular Au nanocrystal sol, the concentration is 1mg / mL, take the granular Au nanocrystal sol 8mL, add 0.2mL of oleylamine, silver nitrate methanol of 10mg / mL After 1mL of the solution, seal it in a 20mL screw bottle, heat it in an oil bath to 60°C, and keep the temperature constant for 16h to obtain a granular AuAg na...

Embodiment 2

[0079] 1. Preparation of granular AuCdS nanocrystals

[0080] (1) At room temperature, stir 0.72mL of oleic acid, 1mL of 1mol / L sodium hydroxide solution, 4mL of acetonitrile and 4mL of water evenly, then add 20mg of chloroauric acid and stir to form a uniform and transparent microemulsion, add 0.1mol / L 80μL of ascorbic acid solution and 13mL of cyclohexane, and continue to stir for 6h, add 4mg of chloroauric acid, 40μL of 0.1mol / L ascorbic acid solution, continue to stir for 3h; stand still, take the organic layer liquid after layering; add to the organic layer liquid 39 mL of absolute ethanol, and centrifuged at 2000 rpm for 7 min to obtain 5 nm granular Au nanocrystals;

[0081] (2) Disperse the granular Au nanocrystals in 40mL of toluene to obtain the granular Au nanocrystal sol, the concentration is 1mg / mL, take the granular Au nanocrystal sol 8mL, add 0.2mL of oleylamine, silver nitrate methanol of 10mg / mL After the solution was 1 mL, it was sealed in a 20 mL capacity s...

Embodiment 3

[0095] 1. Preparation of granular AuCdS nanocrystals

[0096] (1) At room temperature, stir 0.72mL of oleic acid, 1mL of 1mol / L sodium hydroxide solution, 4mL of acetonitrile and 4mL of water evenly, then add 30mg of chloroauric acid and stir to form a uniform and transparent microemulsion, add 0.1mol / L 80 μL of ascorbic acid solution and 13 mL of cyclohexane, and continue to stir for 6 hours, add 8 mg of chloroauric acid, 40 μL of 0.1 mol / L ascorbic acid solution, continue to stir for 3 hours, stand still, take the organic layer liquid after layering; add to the organic layer liquid Ethanol 39mL, and centrifuged at 2000rpm for 7min to obtain 8nm granular Au nanocrystals;

[0097] (2) Disperse the granular Au nanocrystals in 30mL of toluene to obtain the granular Au nanocrystal sol, the concentration is 1mg / mL, take the granular Au nanocrystal sol 8mL, add 0.2mL of oleylamine, silver nitrate methanol of 10mg / mL After 1mL of the solution, seal it in a 20mL screw bottle, heat i...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to an Au@Cu2-deltaX nanoscale crystal and a preparation method and application thereof and belongs to the field of nanoscale materials. The crystal is the nanoscale crystal of a core-shell structure, Au serves as the core, Cu2-deltaX serves as the shell, X is S, Se or Te, and delta is 0-1. The method comprises the steps that Au@CdX nanoscale crystals are dispersed in a non-polar organic solvent, tetrakiscopper hexa-fluorophosph (I) or a solution thereof is added, and reaction liquid is obtained after even mixing; and absolute ethyl alcohol is added for precipitation and centrifugalization to obtain the crystal. The crystal can be applied to the fields of photo-thermal conversion, cancer photo-thermal treatment and the like. The crystal has high light absorptivity and high photo-thermal conversion coefficient at a near infrared region and fills in the technical blank of bimodal surface plasmon resonance (SPR) coupled photo-thermal conversion composite materials. The method can be used for adjusting the size, morphology and the shell layer chemical constituents of the crystal, the conditions are mild, easy and feasible, and a crystal absorption spectrum can be adjusted in a visible light-near infrared light region.

Description

technical field [0001] The present invention relates to a kind of AuCu 2-δ X nanocrystal, its preparation method and application, in the nanocrystal, X is a chemical element: sulfur (S), selenium (Se) or tellurium (Te), and δ is 0 to 1; the preparation method is to use ion exchange method, mixing AuCdX nanocrystals with an organic alcohol solution of Cu(I) salt to obtain the nanocrystals, the preparation method can regulate the size, shape and Cu of the nanocrystals 2-δ The non-stoichiometric ratio of the X shell layer; the nano crystal can be applied to the fields of photothermal conversion and cancer photothermal therapy; it belongs to the field of nanometer materials. Background technique [0002] Today, how to cure tumors and cancers has become one of the most difficult and urgent medical problems facing mankind; and photothermal therapy proposed in recent years is one of the possible effective methods. The photothermal therapy reagent required by photothermal therapy ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): B22F1/02B82Y30/00B82Y40/00
Inventor 张加涛纪穆为徐萌黄柳刘啸
Owner BEIJING INSTITUTE OF TECHNOLOGYGY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com