Preparation method and application of anti-bacterial and anti-inflammation sow thistle ointment

Abstract

The invention discloses a preparation method and application of anti-bacterial and anti-inflammation sow thistle ointment. The anti-bacterial and anti-inflammation sow thistle ointment is obtained by extracting raw materials according to a sequential extraction method, wherein sow thistle serves as a main raw material. The preparation method comprises the following steps: drying the raw materials; smashing the dried raw materials; mixing raw material powder with an ethanol solution to obtain a mixture I; heating the mixture I to boil; carrying out ultrasonic shaking and centrifugal separation to obtain a supernatant fluid; evaporating ethanol in the supernatant fluid, wherein the residue serves as a first extract; dissolving the first extract in water being 4 to 15 times of the first extract in volume to obtain a first extract water solution; conducting extraction with ligarine on the first extract water solution, carrying out extraction with vinegar naphtha and n-butanol sequentially, and evaporating n-butanol after extraction is finished to obtain a thick paste; mixing the thick paste with water being 1 to 15 times of the thick paste in volume to obtain a uniform raw material extracting solution, and mixing the raw material extracting solution with an ointment base to obtain the uniform sow thistle ointment. The sow thistle ointment can be applied to treatment of haemorrhoids, skin damage, acne or mammitis by being smeared on an affected part directly.

Description

technical field [0001] The invention relates to the field of ointment, in particular to a preparation method and application of bitter vegetable ointment with antibacterial and anti-inflammatory effects. Background technique [0002] Bitter cabbage contains a variety of nutrients needed by the human body. Modern medicine has proved that long-term consumption of bitter cabbage and its products can prevent and treat many diseases. The polysaccharides contained in the leaves of bitter herbs have two-way effects of anti-diarrhea and anti-constipation; the plant proteins contained in bitter herbs have good anti-tumor, antibacterial, anti-aging effects; bitter herbs also contain dandelion sterols, choline and other ingredients , has a strong bactericidal effect on hemolytic streptococcus and Staphylococcus aureus drug-resistant strains, and also has a certain killing effect on Shigella, pneumococcus, Pseudomonas aeruginosa, meningococcus, diphtheria bacillus, etc. Hepatitis, cold...

AI Technical Summary

Problems solved by technology

[0006] At present, there are some patents on beverages, health foods or ointments that add bitter herbs to the raw materials for preparation. However, in these existing technologies, the amount of bitter herbs added is very small, and it is difficult to extract bitter herbs due to lack of proper extraction and preparation methods. The active ingredients such as polysaccharides, flavonoids, phenolic acids, and saponins of the vegetable are fully extracted to give full play to the multiple functions of the bitter vegetable, resulting in a high loss of active ingredients and a low utilization rate of the bitter vegetable.