Surface-modified porous-tantalum biological material and preparation method thereof

Abstract

The invention relates to a surface-modified porous-tantalum biological material and a preparation method thereof, and belongs to the technical field of biological medical materials. The surface-modified porous-tantalum biological material and the preparation method have the beneficial effects that an electrochemical anodic oxidation technology is adopted for modifying the surface of a tantalum sheet to prepare a porous tantalum-pentoxide layer with a micro-nano-scale three-dimensional through porous structure, the pore-diameter size can be controlled, the distribution and the communication ofpores are good, and a hydroxyapatite layer is further constructed on the surface of an oxidation layer, so that protein absorption and cell diffusion and proliferation are obviously enhanced, the biocompatibility and the osteoconduction are improved, the microenvironment beneficial to cell growth is generated, the adhesion, the proliferation, the differentiation and the mineralization of primary osteoblasts of human are promoted, the growth of bone tissues into the porous tantalum is promoted to form a unique bone-implant interface, the stability and the function of the implant in the bone tissues are obviously enhanced, the osseointegration of the bone-implant interface is accelerated, and the stability of the implant into the bone tissues is obviously enhanced. The surface-modified porous-tantalum biological material has the advantages of high corrosion resistance and bright application prospect.

Description

technical field

[0001] The invention relates to a surface-modified porous tantalum biomaterial and a preparation method thereof, belonging to the technical field of biomedical materials. Background technique

[0002] Biomedical metal materials are a kind of biomedical materials with metal or alloy as the matrix, also known as surgical metal materials or medical metal materials, which belong to biologically inert materials. They are used for diagnosis, treatment and replacement of damaged tissues and organs Or materials that enhance its function. Common medical metal materials mainly include the following categories: stainless steel, cobalt-based alloys, titanium alloys, etc. Compared with traditional metal materials, ceramic materials, polymer materials, etc., biomedical materials have not been developed for a long time, and people are still relatively unfamiliar with them, but the research on biomedical materials is of great significance to human health.

[0003] The corr...

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