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Cosmetic containing stem cell extract and aloe micromolecular bioactive peptide

A technology for small molecular peptides and cosmetics, applied in the field of cosmetics, can solve the problems of tumorigenicity and rejection, difficult promotion and use of stem cells, reduced differentiation ability, etc., and achieve the effect of improving cell quality, orderly and tightly arranged muscle fibers, and brightening skin tone.

Inactive Publication Date: 2018-08-24
金鑫
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many kinds of stem cells. For the use of stem cells to study anti-aging, people initially focused on embryonic stem cells (ES) because of their ability to proliferate indefinitely and differentiate into three germ layers. However, ES transplantation has ethical controversies and transplantation neoplasticity and rejection
Recent studies have found that adult stem cells also have the ability to differentiate into the three germ layers, among which bone marrow-derived mesenchymal stem cells (BM-MSCs) are the most studied, but BM-MSCs must be differentiated through an invasive approach. Obtained, and with age, the number of cells decreases significantly, and the ability to differentiate decreases, so these types of stem cells are difficult to promote because of their own problems

Method used

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  • Cosmetic containing stem cell extract and aloe micromolecular bioactive peptide
  • Cosmetic containing stem cell extract and aloe micromolecular bioactive peptide

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] The preparation of embodiment 1 aloe small molecule peptide

[0038] (1) fresh aloe leaves are smashed to form mud;

[0039] (2) Centrifuge the pulverized mixture at a speed of 4000r / min for 15min to obtain the first supernatant;

[0040] (3) The first supernatant was centrifuged at a speed of 8000r / min for 10min to obtain the second supernatant containing the aloe active peptide;

[0041] (4) enzymatically hydrolyzing the second supernatant, the temperature of the enzymolysis is 27° C., the time is 3 h, and the enzymolysis liquid is carboxylate hydrolase, protease, lipase and 3-phytase;

[0042] (5) In terms of the weight of the second supernatant, carboxylate hydrolase is carbohydrase, and the addition of carbohydrase is 0.4% of the second supernatant; the addition of protease is 0.5% of the second supernatant The addition of lipase is 0.6% of the second supernatant; the addition of 3-phytase is 0.3% of the second supernatant;

[0043] (6) Centrifuge the enzymatic ...

Embodiment 2

[0047] Example 2 Preparation of Epidermal Stem Cell Extract

[0048] Prepare epidermal stem cells, which were purchased from Huatuo Biotechnology, product number: HT-X2729.

[0049] The preparation method of epidermal stem cell cell extract is as follows:

[0050] Step A: the epidermal stem cells are placed in the cell culture medium for subculture, the cell culture medium is the stem cell culture medium of 89% DMEM+10%FBS+1% double antibody, and the culture condition is 37°C, 5% CO2 culture;

[0051] Step B: select the epidermal stem cells in the logarithmic growth phase, and centrifuge at 1000rpm for 5 minutes to remove the cell culture medium, and obtain the epidermal stem cells separated by centrifugation;

[0052] Step C: Freeze the epidermal stem cells collected by centrifugation, and then thaw them at a temperature not higher than 8°C. Repeat the freeze-thaw operation 2-3 times until the cells are completely broken, and filter them with a filter membrane with a pore si...

Embodiment 3

[0054] The preparation of embodiment 3 cosmetics

[0055] Each component according to the following parts by weight: 1% of the aloe vera small molecule active peptide lyophilized powder of embodiment 1, 20% of sodium lactate, 1% of the epidermal stem cell cell extract of embodiment 2, 10% of D-panthenol, xanthan gum 0.25%, trehalose 15%, fatty alcohol polyoxyethylene ether 4%, potassium sorbate 0.5%, and the balance is deionized water.

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Abstract

The invention provides a cosmetic. The cosmetic is mainly prepared from an epidermal stem cell extract and aloe micromolecular bioactive peptide. The provided human epidermal stem cell extract contains various kinds of life active matter, can revitalize skin cells, activate the self-healing function of human body, supplement and condition aged cells, activate cell functions, increase the number ofcells, improve the cell viability, improve the cell quality, improve the material transportation function of cytomembrane and material interchange capability, recover the normal physiological function of cells, and promote corium layer cells to secrete and synthesize functional molecules such as collagenous fiber, polysaccharide and glycoprotein. The provided aloe micromolecular polypeptide can obviously improve the recovery function of the human epidermal stem cell extract on damaged skin, and the function of delaying cell ageing.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to a cosmetic comprising stem cell extracts and aloe vera small molecule active peptides. Background technique [0002] In modern cities, sun exposure, smog, radiation, makeup and other damage to the skin are ubiquitous, causing various skin problems, such as dull skin, reduced skin elasticity, pigmentation, wrinkles, acne, etc. Skin sensitivity due to non-genetic factors is increasing, and people's demand for protective cosmetics has arisen as the times require, such as skin care lotion, lotion, liquid foundation, sunscreen or barrier cream, which have become must-have cosmetics for modern women one. [0003] Cosmetics can be divided into the following four categories according to the part of use: [0004] 1. Cosmetics for skin use refers to cosmetics for face and skin. Such cosmetics as various creams, bath agents. [0005] 2. Hair cosmetics refer to special cosmetics for hair. Such ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/99A61K8/98A61K8/64A61Q19/00A61Q19/08A61Q19/02
CPCA61K8/99A61K8/645A61K8/985A61Q19/00A61Q19/004A61Q19/02A61Q19/08
Inventor 金鑫
Owner 金鑫
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