Gynecological antibacterial gelatin based on green antibacterial materials, and preparation method of gynecological antibacterial gelatin based on green antibacterial materials

Abstract

The invention discloses gynecological antibacterial gelatin based on green antibacterial materials. The antibacterial gelatin is characterized by comprising the following components in parts by weightof 0.5-1.5 parts of hyperbranched glycol chitosan, 1-3 parts of 2,3,5,4'-tetrahydroxystilbene-2-O-glucoside/citronellal/(Z)-2-(2-tert-butoxycarbonylaminothiazol-4-yl)-2-pentenoic acid/limonene-1,2-epoxide/allyloxypolyethyleneglycol copolymers, 3-5 parts of hyperbranched polyglycerol, 0.1-0.4 part of hypericum perforatum extracts, 0.1-0.3 part of porous cyclodextrin type metal organic frameworks,0.2-0.5 part of Chinese herbal medicine extracts, 0.1-0.3 part of pH adjusting agents and 50-60 parts of water. The invention also discloses a preparation method of the gynecological antibacterial gelatin based on green antibacterial materials. The gynecological antibacterial gelatin based on green antibacterial materials, disclosed by the invention, is notable in antibacterial and anti-infectioneffects, good in performance stability, excellent in biocompatibility, excellent in treatment effects of gynecological inflammation, capable of promoting regeneration and relieving pain, and being small in side effects, and safe to use, and has higher market promotion and application value.

Description

technical field [0001] The invention relates to the technical field of medical nursing materials, in particular to a gynecological antibacterial gel based on green antibacterial materials and a preparation method thereof. Background technique [0002] In recent years, with the development of society and the constant changes in people's lifestyles and behaviors, the prevalence of gynecological inflammation is gradually increasing, especially in women of childbearing age and married women. Gynecological inflammation refers to various inflammations that occur in female reproductive organs, including vulvitis, vaginitis, cervicitis, pelvic inflammatory disease, etc. It is a common and frequently-occurring disease. Once women get sick, it will affect their normal daily life and be detrimental to their physical and mental health. If it cannot be treated in time, the condition will deteriorate, and it can also lead to female infertility, and even premature aging, which seriously a...

AI Technical Summary

Problems solved by technology

[0004] When the common gynecological antibacterial gel in the prior art is injected into the vagina, when it encounters salt and electrolytes in the human body, it is easy to become thin immediately, and the effective drugs are easy to flow out naturally before they can stay on the vaginal wall to play an antibacterial effect, resulting in gynecological Gel has low potency and poor therapeutic effect

Moreover, most of the gynecological antibacterial gel drugs on the market are antibiotic drugs, which are very irritating to the skin, and the skin is prone to allergic reactions. Using it for a long time will not only cause certain damage to the body, but also the body will develop drug resistance, which will affect the quality of the drug. effect and therapeutic effect, and the biocompatibility and biodegradability of the artificially synthesized macromolecular gel matrix are poor, which affects its use as a gynecological external gel

[0005] Patent CN102204880A discloses a gynecological topical disinfectant gel and its preparation method. The gel matrix of the gel itself does not contain bactericidal ingredients, and it is necessary to add bactericides or other surface active substances to have anti-inflammatory effects. Good bactericidal effect, but the added bactericidal ingredients are likely to irritate the skin, and it is easy to affect the normal flora and acid-base balance in the vagina, and it is easy to cause drug dependence