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Preparation method of natural anti-wrinkle cosmetic material

An anti-wrinkle cosmetic, natural technology, applied in the preparation method of peptides, cosmetic preparations, cosmetics, etc., can solve environmental pollution and other problems

Active Publication Date: 2020-11-27
时垠(上海)生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the irritation, allergies, and safety of synthetic cosmetics have aroused people's concerns, and at the same time, the production process has caused pollution to the environment, so people began to pursue natural cosmetics with good efficacy, few side effects, and high safety.

Method used

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  • Preparation method of natural anti-wrinkle cosmetic material

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] Take fresh silk and mix it with a mass fraction of 1% sodium carbonate solution at a mass ratio of 1:5, place it in a water bath at 120°C for 1 hour, let it cool down to room temperature, filter and collect the filter cake, and vacuum freeze-dry To obtain dry granules, weigh 85 parts by weight of 45% ethanol solution, 10 parts of calcium chloride and 6 parts of dry granules in Erlenmeyer flasks, stir and mix them and place them at 75°C to insulate and dissolve. The solution was collected and dialyzed, the dialysate was collected and placed in a rotary evaporation process at 35°C, and the rotary evaporation was reduced to 1 / 5 of the original volume to obtain silk fibroin particles; by weight, 45 parts of deionized water, 10 1 part of silk fibroin granules and 1 part of phospholipid were placed in an Erlenmeyer flask, stirred and mixed and placed in a homogenizing device, homogenized at 25 MPa for 25 minutes, and the phospholipid complex solution was collected; then weighe...

Embodiment 2

[0067] Take fresh silk and mix it with a mass fraction of 1% sodium carbonate solution according to the mass ratio of 1:5, and place it in a water bath at 125°C for 1 hour, let it cool down to room temperature, filter and collect the filter cake, and vacuum freeze-dry To obtain dry granules, weigh 87 parts by weight of 45% ethanol solution, 12 parts of calcium chloride and 7 parts of dry granules respectively in Erlenmeyer flasks, stir and mix them and place them at 77°C to insulate and dissolve. The solution was collected and dialyzed, the dialysate was collected and placed in a rotary evaporation process at 40°C, and the rotary evaporation was reduced to 1 / 5 of the original volume to obtain silk fibroin particles; in parts by weight, 47 parts of deionized water, 12 1 part of silk fibroin granules and 1 part of phospholipid were placed in an Erlenmeyer flask, stirred and mixed and placed in a homogenizing device, homogenized at 27 MPa for 27 minutes, and the phospholipid compl...

Embodiment 3

[0070] Take fresh silk and mix it with a mass fraction of 1% sodium carbonate solution at a mass ratio of 1:5, place it in a water bath at 130°C for 2 hours, let it cool down to room temperature, filter and collect the filter cake, and vacuum freeze-dry To obtain dry granules, weigh 90 parts by weight of 45% ethanol solution, 15 parts of calcium chloride, and 8 parts of dry granules in Erlenmeyer flasks, stir and mix them, and place them at 80°C to insulate and dissolve. The solution was collected and dialyzed, the dialysate was collected and placed in a rotary evaporation process at 45°C, and the rotary evaporation was reduced to 1 / 5 of the original volume to obtain silk fibroin particles; by weight, 50 parts of deionized water, 15 1 part of silk fibroin granules and 2 parts of phospholipids were placed in an Erlenmeyer flask, stirred and mixed and placed in a homogenization device, homogenized at 30 MPa for 30 minutes, and the phospholipid complex solution was collected; then...

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Abstract

The invention relates to a preparation method of a natural anti-wrinkle cosmetic material, and belongs to the technical field of cosmetic materials. In the technical scheme, anti-wrinkle natural combined materials are mainly compounded, an auxiliary transdermal micro-emulsion gel material is used for sufficiently treating cells in the skin, meanwhile, an ellagic acid substance adopted by the invention can effectively inhibit the effect of an elastase material, and a sea cucumber extract polypeptide material is adopted for modification, so that cell level proliferation and repair are effectively promoted, skin aging is fundamentally delayed, meanwhile, the viscosity of the micro-emulsion is improved through gel, the medicine maintaining time is prolonged, the irritation of the medicine is reduced, the micro-emulsion acts on the surface of the skin for a long time, and the anti-wrinkle effect is further improved.

Description

technical field [0001] The invention relates to a preparation method of a natural anti-wrinkle cosmetic material, which belongs to the technical field of cosmetic materials. Background technique [0002] Skin aging is a continuous and gradual physiological process. In appearance, it is manifested as dry skin, sagging, wrinkles, and pigment deposition. The occurrence of aging includes many factors, which can be roughly divided into endogenous and exogenous oxidative damage. Endogenous oxidative damage is mainly controlled by genetics, free radical damage and metabolic disorders. Exogenous oxidative damage is mainly affected by the environment, such as under tension and stress, or by unhealthy living habits such as excessive drinking and smoking, as well as environmental pollution and ultraviolet radiation. Oxygen is a key factor in the production of free radicals, a hallmark of skin aging. In the exogenous oxidative damage, the damage of ultraviolet rays is very large, whi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/98A61K8/64A61K8/55A61K8/49A61K8/73A61K8/06A61Q19/08A61Q19/00C07K14/435C07K1/34C12P21/06
CPCA61K8/9789A61K8/987A61Q19/08A61K2800/84A61K2800/805A61K8/64A61K8/553A61K2800/82A61K8/20A61K8/604A61K8/73
Inventor 严志晶
Owner 时垠(上海)生物科技有限公司
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