Gynecological antibacterial temperature-sensitive gel and preparation method thereof

Abstract

The invention provides a temperature-sensitive gel for gynecological antibacterial nursing. Based on the total amount of the temperature-sensitive gel for gynecological antibacterial nursing, the temperature-sensitive gel comprises the following components in percentage by weight: 1.2%-17% of a humectant, 0.2%-0.5% of chlorhexidine acetate, 1.11%-9.4% of a traditional Chinese medicine antibacterial compound, 16%-30% of a temperature-sensitive gel, 3.2%-5.2% of a freshener and 0.3%-0.6% of a preservative, 0.3%-5.05% of a lubricant and 46.07%-61.7% of deionized water, and the temperature-sensitive gel is any two of glucomannan, poloxamer 407 and poloxamer 188. Through combination of the chemical bacteriostatic agent and the main bacteriostatic agent, the gynecological antibacterial temperature-sensitive gel has a more milder and more thorough antibacterial effect, the gelation temperature can be adjusted, the gel is convenient to use and more suitable for human body, and all the components are safe and reliable, and the gel is free of irritation to the human body and free of accumulated toxicity.

Description

technical field [0001] The invention relates to the technical field of external gynecological health care products, in particular to a gynecological antibacterial and temperature-sensitive gel and a preparation method thereof. Background technique [0002] With the growth of women's age and the increase of life pressure, there are more and more gynecological diseases or health problems, which not only affect women's physical health, but also have a negative impact on women's mental health. More and more women are troubled by gynecological diseases such as abnormal leucorrhea, genital itching, irregular menstruation, leucorrhea odor, and vaginal dryness. In the epidemiological survey results of common gynecological diseases, the order of prevalence of reproductive tract infection is as follows: chronic cervicitis 39.3%, vaginitis caused by various causes 15.9%, genital Chlamydia trachomatis infection 5.4%, chronic pelvic inflammatory disease 4.1% %, vulvitis 1.5%, etc. The ...

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Problems solved by technology

The special physiological structure of women is vulnerable to the attack of pathogens such as Candida albicans, Staphylococcus aureus, Streptococcus, Escherichia coli, viruses, etc. Poor living habits or high work pressure may make some patients have poor immunity, resulting in These gynecological diseases are usually incurable for a long time, which brings great inconvenience to women's life and work

[0003] At present, there are many kinds of drugs for treating gynecological inflammation. Oral drugs are mainly absorbed through the stomach and enter the vagina through blood circulation and kill bacteria. The onset time is slow, and long-term use is required to show the effect; external antibacterial drugs for treating gynecological inflammation also include suppositories. , lotions, sprays, etc. are inconvenient to use and feel burdensome, but most of the drugs will damage the vaginal environment and the secretion function of the mucous membrane itself, which will lead to a decline in the local immunity of the reproductive system and may cause pathogenic bacteria to Drug resistance and drug resistance are produced, and finally inflammation recurs; how to solve gynecological inflammation from itself and achieve the dual purpose of antibacterial and nursing has become an urgent problem to be solved

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