51 results about "Glucomanna" patented technology

The invention discloses a bi-crosslinking gelatin-based hydrogel wound dressing as well as a preparation method and application thereof, and belongs to the technical field of biomedical materials. The preparation method disclosed by the invention comprises the following steps: mixing a gelatin solution and an oxidized konjac glucomannan solution, heating and stirring to obtain a hydrogel precursor solution; and mixing the hydrogel precursor solution with a borax solution to obtain the bi-crosslinked gelatin-based hydrogel wound dressing. According to the method, oxidized konjac glucomannan and gelatin are subjected to Schiff base and Schiff base crosslinking, borax is further added to introduce a dynamic boric acid ester bond effect to enhance a three-dimensional network of the hydrogel, and the dynamic reversible Schiff base effect and the boric acid ester bond effect are enhanced, so that the pore diameter and the swelling ratio of the hydrogel are increased, and the gel strength of the hydrogel is enhanced; due to the good self-healing injectable performance, biodegradability and mechanical property of the hydrogel, the hydrogel can be used as a wound dressing for irregular deep skin wounds, and the technical problem that existing hydrogel is insufficient in treatment of irregular wounds is solved.

The invention discloses a fat-reducing and weight-reducing medicinal and edible food and a preparation method thereof, the composition comprises a lotus leaf extract, a Pu'er tea fermentation product, a hovenia dulcis thunb extract, konjac glucomannan, a pepper extract, fermented mulberry leaf powder, a prebiotic compound and oyster peptide, and the invention relates to the technical field of functional food. According to the fat-reducing and weight-reducing medicinal and edible food and the preparation method thereof, efficient fat reduction is realized through a four-dimensional synergistic effect (regulating lipid metabolism, inhibiting fat absorption, promoting energy consumption and improving intestinal flora).

The invention discloses a preparation method of a konjac glucomannan-based coating film. The preparation method comprises the following steps: (1) preparing materials: 4 parts of konjac glucomannan, 3-4 parts of chitosan, 2-3 parts of high-ester pectin, 0.5-0.6 part of calcium carbonate and 0.8-1.1 parts of glycerol; (2) chitosan is dissolved in a 1% organic acid solution, then konjac glucomannan and high-ester pectin are added and stirred evenly to form a mixed solution, and the mass fraction of solute in the mixed solution is 2-3%; and (3) carrying out modification treatment on the mixed solution, then adding glycerol and calcium carbonate, and uniformly stirring to obtain the film coating solution. The coating film is not easy to dissolve, has excellent mechanical properties, and can keep fruits fresh by inhibiting ethylene synthesis, maintaining mango quality, delaying fruit ripening and maintaining fragrance release.

The invention relates to the field of konjak food, provides konjak gel food as well as a preparation method and application thereof, and aims to solve the problems of poor stability, insufficient brittleness and poor antibacterial property of existing konjak gel food. According to the gel food, phosphorylated konjac glucomannan serves as a main body, chitosan / microcrystalline cellulose composite filler, carrageenan, sodium alginate, calcium salt, citrate and other auxiliary materials are added, a multi-cross-linked network structure is constructed through the synergistic effect of multiple components, and the stability and mechanical performance of gel are remarkably enhanced. In the preparation process, a temperature gradient control strategy is adopted, and ordered construction and layer-by-layer curing of a gel network are achieved. The obtained product has high gel strength, excellent brittleness, low bleeding rate and excellent antibacterial performance, can be widely applied to functional food simulating the mouth feel of animal cartilage, and has good storage stability and sensory quality.

The invention discloses a deacetylated konjac glucomannan composite hydrogel and a preparation method thereof, the raw materials comprise deacetylated konjac glucomannan, agar, guar gum and water, the water and polysaccharide powder are mixed according to a certain proportion, magnetically stirred for 15 minutes, then placed in a water bath kettle at 90 DEG C for water bath for 30 minutes, taken out and cooled to room temperature, and the deacetylated konjac glucomannan composite hydrogel is obtained. And refrigerating in a refrigerator at 4 DEG C for 24 hours. The high-elasticity deacetylated konjac glucomannan composite hydrogel is obtained by controlling the adding amount of raw material powder, the deacetylation degree, the stirring time, the water bath temperature and the water bath time, improving the problems of poor gel strength, overlarge viscosity and poor thermal stability of konjac glucomannan single gel and remarkably improving the elasticity and the water-holding capacity of the gel.

A process for preparing a supramolecular carrier photosensitizer for photodynamic therapy and a formulation thereof is disclosed for prevention, treatment, anti-inflammatory and sterilization of oral dental diseases. Supramolecular carrier consists of refined lignin, glucomannan, cysteine, and sodium benzoate at a mass ratio of 0.1-1.0%: 0.5-3%: 0.1-0.5%: 0.05%, and the balance of water. Aqueous solutions of refined lignin, glucomannan, cysteine and sodium benzoate are prepared, and a pH value of combined solution is adjusted to 6.5, so that dissolved alkali lignin is precipitated to form an efficient and stable three-dimensional polymer network skeleton, and rich hydrogen bonds are facilitated to be formed between the same molecules and different molecules of lignin and glucomannan, thereby forming a supramolecular carrier formulation loaded with the photosensitizer. It ensures long-term storage stability of physicochemical traits of formulation, which is conducive to rapidly promoting application of PDT in anti-inflammatory and sterilization treatment of oral dental diseases.

The invention provides a bagasse nanocellulose-based antibacterial composite film as well as a preparation method and application thereof, and belongs to the technical field of food packaging materials. The preparation method comprises the following steps: sequentially carrying out alkali treatment, bleaching treatment and acid treatment on bagasse to obtain bagasse microcrystalline cellulose; the preparation method comprises the following steps: reacting bagasse microcrystalline cellulose, absolute ethyl alcohol and chloroacetic acid, and shearing after the reaction is finished, so as to obtain chloroacetic acid grafted and modified bagasse nano cellulose; dispersing konjac glucomannan in water to obtain a konjac glucomannan dispersion liquid, then adding citrus essential oil and bagasse nanocellulose into the konjac glucomannan dispersion liquid to carry out a secondary reaction, adding a plasticizer after the reaction is finished, and adjusting the pH value with citric acid to obtain a film forming liquid; and drying the film forming liquid to obtain the bagasse nano cellulose based antibacterial composite film. The antibacterial composite film prepared by the invention has excellent tensile strength, water vapor permeability and antibacterial activity, and can be used for monitoring the freshness of high-protein food.

The invention relates to the field of biomedical materials, and discloses natural bio-based hydrogel as well as a preparation method and application thereof. Comprising the following preparation steps: performing alkaline modification on konjac glucomannan to obtain deacetylated konjac glucomannan; carrying out ammoniation modification on gelatin to obtain ammoniated gelatin; treating the amomum villosum volatile oil with a cosolvent to obtain an amomum villosum volatile oil dispersion liquid; and mixing the deacetylated konjac glucomannan and ammoniated gelatin, then adding the amomum villosum volatile oil dispersion liquid, and fully reacting to obtain the natural bio-based hydrogel. After the gelatin is ammoniated and modified, the content of free amino groups is increased by about 220%, and the network stability is improved. The energy storage modulus of the prepared hydrogel can reach 38.25 Pa, and the prepared hydrogel is excellent in mechanical property. The scavenging rate of the hydrogel to DPPH free radicals reaches up to 65.9%, and the hydrogel has good oxidation resistance.

The absorbent material may include glucomannan, as well as biodegradable and / or non-biodegradable additives / substrates. The biodegradable additives may be corn, walnut shells, newspapers, grass, wood chips, x-DDG, etc.

The invention discloses highly acetylated glucomannan and application thereof in preparation of a product with an effect of relieving prediabetes mellitus, and belongs to the technical field of medicines. In-vivo experiments prove that the glucomannan with high acetylation degree has the effect of relieving the prediabetic stage, which is specifically reflected in weight gain of mice in the prediabetic stage, regulation of blood glucose metabolism, improvement of glucose tolerance and insulin resistance, regulation of blood lipid metabolism, protection of liver and pancreatic tissues and reduction of epididymal fat cell size. The invention provides an important basis for developing a dietary formula suitable for prediabetic patients, and provides a new method for prevention and management of diabetes mellitus.

The application discloses a kind of fermented whipped cream and method prepared by using two-phase oil gel, belong to fermentation milk processing technical field.The application is prepared oil phase gel with enzymolysis coconut oil, rapeseed protein as raw material, and prepared water phase gel with selenized carrageenan and oxidized konjac glucomannan, then two-phase oil gel is formed by processing;Cream raw material is pre-fermented by saccharomyces cerevisiae, and cream microspheres are obtained by high-pressure homogenization, then fermented whipped cream is obtained by mixing two-phase oil gel and compound lactic acid bacteria.The application constructs stable crosslinking network by cysteine, gives two-phase oil gel good elasticity and stability, cream microspheres can avoid sedimentation and aggregation, and compound lactic acid bacteria fermentation not only promotes the system to form uniform gel network, but also retains characteristic flavor.The fermented whipped cream prepared by the application has uniform texture and rich and lasting flavor, has nutrition and taste advantage, can effectively solve the problem of loose structure and easy flavor loss of traditional fermented whipped cream, and has good industrial application prospect and market value.

The invention discloses a formula of a cold compress patch capable of being bagged on line and a preparation process of the cold compress patch, the specific formula comprises the following raw materials: oil raw materials comprise 400-500 g of glycerol, 300-350 g of sodium polyacrylate, 6-9 g of dihydroxyaluminum aminoacetate and 7-8 g of disodium salt; the water item raw materials comprise 5140 g of purified water, 13.2 g of tartaric acid, 30 g of a cool feeling agent, 60 g of ethyl alcohol, 0.6 g of potassium sorbate and 0.4 g of glucomannan. According to the formula, on the basis of ensuring the water locking effect of the hydrogel, the use amount of glycerol is reduced through the preparation process, so that the material cost for producing the cold compress patch is saved. The cold compress patch is arranged at the joint of the base body layer and the sealing layer, the closed bonding ring is formed through heat sealing, the closed storage space is formed in the inner side area in the bonding ring and used for containing hydrogel, the gel is prevented from overflowing through the closed bonding ring, airing and curing treatment is not needed, field stacking is reduced, and the cost is reduced. And meanwhile, the moisture of the gel can be locked, online bagging can be achieved, the product process steps are reduced, and the delivery speed is increased. A spacing gap with a certain interval is formed on the outer side of the bonding ring, so that the sealing layer can be conveniently separated from the base body layer.

The invention belongs to the technical field of glass fiber surface treating agents, and discloses a preparation method of a konjac glucomannan modified pea starch glass fiber impregnating compound, which comprises the following steps: adding water into pea starch, and gelatinizing at 85 DEG C for 30 minutes to prepare a pea starch solution; the preparation method comprises the following steps: adding water into konjac glucomannan, and stirring and dissolving at 60 DEG C to prepare a konjac glucomannan solution; mixing the pea starch solution and the konjac glucomannan solution according to a mass ratio of 4: 1, adding a silane coupling agent, and carrying out esterification grafting reaction at 75 DEG C for 1 hour to obtain a mixed solution; and adding a plasticizer, a lubricant and an antistatic agent into the mixed solution, and homogenizing at a high speed to obtain the impregnating compound. According to the preparation method, a pea starch and konjac glucomannan full bio-based system is adopted, the impregnating compound is prepared through a water-phase esterification reaction, the process is simple, the reaction condition is mild, a three-dimensional network is formed through esterification crosslinking of konjac glucomannan linear molecules and pea starch branched chains, and the compactness of a film layer is improved.

The present invention relates to the field of anti-inflammatory and antiseptic formulations for prevention and treatment of dental diseases in the department of stomatology, and specifically to a preparation process for a supramolecular carrier photosensitizer for photodynamic therapy, and a formulation thereof. A supramolecular carrier is composed of refined lignin, glucomannan, cysteine, and sodium benzoate at the mass ratio of 0.1-1.0%:0.5-3%:0.1-0.5%:0.05%, with the balance of water. The preparation process comprises: first respectively preparing aqueous solutions of refined lignin, glucomannan, cysteine, and sodium benzoate; then adjusting the pH value of a mixed solution to 6.5, so that dissolved alkali lignin is separated out, so as to form an efficient and stable three-dimensional polymer network framework; and promoting formation of abundant hydrogen bonds between identical molecules and different molecules of lignin and glucomannan, so as to prepare a photosensitizer-loaded supramolecular carrier formulation. The present invention can ensure the long-term storage stability of the physical and chemical properties of the formulation, and is conducive to quickly promoting the application of PDT in the anti-inflammatory and sterilization treatment of dental diseases in the department of stomatology.

The present invention relates to the technical field of adhesives, and in particular to an environmentally friendly glue for children's picture books based on natural plant extracts, and a preparation method and application thereof. The glue comprises the following components: 10-15 parts by weight of loofah extract, 45-55 parts by weight of dynamic network base liquid, 0.5-1.5 parts by weight of xanthan gum, 1.2-2.3 parts by weight of nanocellulose, 0.3-0.6 parts by weight of methylcellulose, 2-4 parts by weight of aloe vera gel, 1-2 parts by weight of glycerol, 2-4 parts by weight of sorbitol, and 0.3-0.7 parts by weight of rosemary extract; wherein the dynamic network base liquid is obtained by mixing oxidized konjac glucomannan, silk fibroin, tannic acid, and ferric chloride. The present invention adopts a dynamic multiple cross-linked network design, forms a dynamic covalent bond by oxidizing konjac glucomannan and silk fibroin, combines tannic acid-Fe³⁺ coordination complexation, and constructs a three-dimensional network with a synergistic effect of dynamic covalent bonds and coordination bonds.

The invention relates to an application of glucomannan in preparation of a product for preventing or treating radioactive intestinal injury. The relative molecular weight of the glucomannan disclosed by the invention is 10 to 1,000 kD; monosaccharide components of the glucomannan comprise mannose and glucose; the glucomannan is formed by connecting mannose and glucose through a beta-1, 4-glucosidic bond, and has a glucose branched chain structure and acetyl modification. The glucomannan disclosed by the invention can be used for treating radioactive intestinal injury, directly protecting an organism from small intestine DNA injury and small intestine crypt stem cell injury caused by ionizing radiation, and inhibiting oxidative stress, inhibiting mitochondrial apoptotic cell apoptosis regulatory factors and regulating expression of inflammatory factors in intestinal tissues by regulating an in-vivo SOD (superoxide dismutase) value; and the intestinal flora is kept stable under the influence of ionizing radiation.

The invention discloses an intestinal antioxidant peptide and zinc glycan complex as well as a preparation method and application thereof, and belongs to the technical field of functional foods and medicines. The complex is insoluble in water, has better antioxidant activity, can play an antioxidant role in intestinal tracts and can promote intestinal health. According to the intestinal antioxidant peptide and zinc glycan complex, antioxidant polypeptides such as polyglutamic acid, polyaspartic acid, whey protein and glutathione and zinc with an antioxidant effect are creatively selected as antioxidant functional components, and glucomannan molecules are used as a three-dimensional network wall material, so that the antioxidant functional components are successfully fixed; digestion and absorption are prevented, and an anti-oxidation effect can be achieved in the enteric cavity. The preparation process solves a plurality of technical problems of molecular cross-linking entanglement and polypeptide solidification.

The present invention discloses the application of konjac glucomannan in the preparation of high internal phase Pickering emulsions, which relates to the technical field of food industry; the high internal phase Pickering emulsion uses myofibrillar protein as the protein raw material. The present invention also provides a method for preparing a high internal phase Pickering emulsion, which comprises the following steps: (1) A myofibrillar protein solution and a konjac glucomannan solution are mixed and homogenized to obtain a myofibrillar protein / konjac glucomannan mixed system; (2) Using the myofibrillar protein / konjac glucomannan mixed system as the aqueous phase, it is mixed with the oil phase and homogenized to prepare the high internal phase Pickering emulsion. The present invention finds through research that konjac glucomannan can improve the physical properties of high internal phase Pickering emulsions stabilized by myofibrillar protein by changing the interfacial adsorption and network structure.

The invention discloses sprayable hydrogel for tumor postoperative adhesion prevention and immunotherapy as well as a preparation method and application of the sprayable hydrogel, and belongs to the technical field of biomedical materials. The sprayable hydrogel comprises a hydrogel matrix material and a nano material dispersed in the hydrogel matrix material; wherein the nano material is an ovalbumin liposome; the hydrogel matrix material is prepared from oxidized konjac glucomannan and methacrylated gelatin. According to the sprayable hydrogel, on a biological tissue interface, one side has stable tissue adhesion capacity, and the other side keeps free from surrounding tissues; due to the asymmetric adhesion design, the unexpected adhesion problem caused by indifference adhesion of traditional hydrogel can be reduced; in addition, drug release is doubly regulated and controlled through liposome and a gel network, antigen burst release is avoided, immune cell activation is remarkably promoted, and then the tumor recurrence rate is remarkably reduced.

The application relates to the technical field of concrete admixtures, and particularly discloses a concrete admixture for inhibiting negative effects of flocculants and a preparation method and application thereof. The concrete admixture for inhibiting negative effects of flocculants comprises the following components in mass fractions: 1-2 parts of a water reducing agent, 1-1.5 parts of hydroxyethylidene diphosphonic acid, 0.1-0.5 parts of sodium monofluorophosphate, 0.1-0.5 parts of glucomannan and 0.05-0.1 parts of turpentine. The concrete admixture for inhibiting negative effects of flocculants can effectively neutralize or weaken the adverse effects of flocculants on the performance of concrete, while keeping good workability and mechanical properties of the concrete, so that the long-term durability of the concrete is comprehensively improved.

A fat composition for meat analogues comprises a glucomannan gum e.g. konjac gum, a fat, a browning agent e.g. a dextrin, a coagulating agent e.g. calcium hydroxide, and water. The composition prefera

The present invention belongs to the field of biomaterial preparation technology, and specifically relates to a sea squirt nanocellulose-enhanced rapid hemostatic sponge with photothermal antibacterial effect and a preparation method thereof. The present invention uses chitosan and oxidized konjac glucomannan as matrix materials, nano sea squirt cellulose and polydopamine nanoparticles as main reinforcing raw materials, firstly modifies konjac glucomannan into oxidized konjac glucomannan by oxidation, and constructs sea squirt nanocellulose / polydopamine polysaccharide-based scaffold material, which not only has a good infrared light response antibacterial effect, but also has a uniform three-dimensional macroporous structure that enables the sponge scaffold to achieve the function of rapid hemostasis, and can effectively scavenge free radicals and promote wound healing. The prepared sponge has good biocompatibility and no cytotoxicity, and is expected to become a new type of rapid hemostasis and effective antibacterial scaffold material.

The invention provides a method of promoting weight management in a mammal comprising administering to the mammal a composition comprising at least one weight loss agent and at least one mitochondrial enhancer. The weight loss agent can be selected from the group consisting of psyllium, guar gum, capsaicin, chitosan, caffeine, gamboge, mume, capsaicin, yohimbine, butterfly pea, glucomannan, African mango, guarana, pyruvate, carnitine, beta-glucan, fucoxanthin, raspberry ketone, white kidney bean, kola nut, chromium, ginseng, psyllium, St. John's wort, dandelion, hydroxycitric acid, conjugated linoleic acid, green tea, black tea, coffee bean extract, forskolin, and bitter orange. The mitochondrial enhancer can be selected from the group consisting of beetroot extract, nitrate, idebenone, nicotinamide riboside, elamipretide, vitamin C, vitamin D, vitamin E, thiamine, riboflavin, magnesium, calcium, phosphate, phospholipid, creatine, pyruvate, coenzyme Q10, NADH, niacin, L-carnitine, dichloroacetate, curcumin, schisandrin, and resveratrol. Compositions for weight management are also provided.

An oral care composition is described herein. An oral care composition comprising at least two thickening polymers selected from the group consisting of xanthan gum, tara gum, glucomannan, carrageenan and algin; and glycerol, wherein the oral care composition has a viscosity of from about 0.1 to about 1000 Pas. The oral care compositions of the present disclosure have improved rheological properties.

A mix for liquid batter containing processed starch, 0.1-0.8 mass% of glucomannan, and 0.1-0.8 mass% of xanthan gum.

The present invention provides methods of producing a glucomannan scaffold having uniform porosity and interconnectivity. The scaffold is prepared by maintaining a glucomannan gel under conditions prescribed to meet a length of time in the solidification phase. The method improves product consistency, while reducing manufacturing waste. The resulting glucomannan scaffold is capable of promoting cell growth and suitable for three-dimensional tissue culture and engineering.

The invention belongs to the technical field of food processing, and provides plant meat based on compounding of camellia seed grease and polysaccharide and a preparation method of the plant meat. The preparation method comprises the following steps: dispersing a camellia seed grease body in water to obtain a grease body emulsion; the preparation method comprises the following steps: mixing plant drawing protein with water, and sequentially carrying out hydration, stirring, grinding, sieving and ultrasonic treatment to obtain a fibrous system; mixing the grease body emulsion, the fibrous system and polysaccharide, and performing crosslinking to obtain the plant meat, the polysaccharide comprises one or more of gellan gum, konjac glucomannan and chitosan. According to the invention, the camellia seed grease body is integrated into the protein matrix as an active filler, and a dense gel network is formed by utilizing the enhanced hydrogen bond and hydrophobic interaction between the protein matrix and polysaccharide, so that the hardness and elasticity of the plant meat are remarkably improved; meanwhile, the texture and the rheological property of the plant meat are further enhanced by utilizing the excellent compatibility of the polysaccharide with the camellia seed grease body and the protein matrix and through the structure strengthening and water molecule fixing effects.

The invention provides oxidized konjac glucomannan hydrogel for promoting wound healing of diabetic patients and a preparation method of the oxidized konjac glucomannan hydrogel, and belongs to the technical field of biomedical engineering. According to the invention, resveratrol is loaded in a dynamic cross-linked hydrogel matrix formed by carboxymethyl chitosan and oxidized konjac glucomannan, so that a multi-mechanism synergistic composite hydrogel is formed; the prepared resveratrol-loaded oxidized konjac glucomannan hydrogel is safe and efficient, has good oxidation resistance and a function of promoting wound healing, and has good development and application prospects.

The invention discloses Pickering emulsion gel with stable sardine protein / konjac glucomannan compound and application of the Pickering emulsion gel, and belongs to the technical field of Pickering emulsion. According to the preparation method, sardine protein is taken as a raw material, konjac glucomannan is added to form a compound, the Pickering emulsion is stabilized based on the gel characteristic of the compound, and the stable Pickering emulsion gel can be prepared only through a one-step emulsification method. A good physical barrier can be provided for active ingredients, and the retention rate of astaxanthin under the conditions of storage, heating and ultraviolet irradiation is increased. Meanwhile, the emulsion prepared by the method disclosed by the invention has an intestinal flora probiotic effect. The emulsion gel is easy to prepare, raw materials are green and safe, and the emulsion gel can be used for delivering active ingredients and can be applied to the field of food.

The present application relates to the konjac food field, provide a kind of konjac gel food and preparation method and application, to solve the poor stability of existing konjac gel food, insufficient brittleness and poor antibacterial performance Problem.The gel food is mainly based on phosphorylated konjac glucomannan, adding chitosan / microcrystalline cellulose composite filler, carrageenan, sodium alginate, calcium salt and citrate and other auxiliary materials, by the synergistic effect of multiple components Multiple crosslinking network structure is constructed, which significantly enhances the stability and mechanical properties of gel. Temperature gradient control strategy is used in the preparation process, to realize the ordered construction and layer-by-layer solidification of gel network. The product has high gel strength, excellent brittleness, low water separation rate and excellent antibacterial performance, and can be widely used in functional foods simulating the taste of animal cartilage, with good storage stability and sensory quality.