General polymer fluorescent platform applicable to FRET fluorescent probe donor and application of general polymer fluorescent platform

A technology of fluorescent probes and polymers, which is applied in the fields of organic chemistry and polymer material chemistry, can solve problems such as complex synthesis processes, achieve low cost, simple and easy synthesis, and achieve the effect of visual detection by naked eyes
CN113402655AActive Publication Date: 2021-09-17DALIAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
DALIAN UNIV
Publication Date
2021-09-17

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Abstract

The invention relates to a general polymer fluorescent platform applicable to a FRET fluorescent probe donor and application of the general polymer fluorescent platform, belonging to the technical fields of organic chemistry and high polymer material chemistry. According to the invention, methyl methacrylate and 4-allyloxy benzaldehyde are polymerized according to a reasonable ratio, and a coumarin fluorophore is further introduced through an efficient Schiff base reaction to prepare a general polymer blue-light platform MS-1 in the invention. The MS-1 is prepared from MS-1 and MS-2 step by step. The general polymer fluorescent platform prepared from the coumarin fluorophore has the advantages of easily available raw materials, simple and easy synthesis and low cost. When the general polymer fluorescent platform is combined with a mature long-wavelength fluorescent probe, proportional fluorescence detection of target molecules can be realized, and even visual detection with naked eyes can be realized through colors.
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Description

technical field

[0001] The invention belongs to the technical field of organic chemistry and macromolecule material chemistry, and specifically relates to a polymer universal fluorescent platform that can be used as a FRET fluorescent probe donor and its application. Background technique

[0002] Since the 21st century, due to the great application potential of optical fiber sensors in industrial analysis, biochemistry, and drug detection, such sensors have been paid close attention to (Adv Optical Mater. 2021, 9, 2001913). Designing such a sensor requires new functional materials with high sensitivity, which is not easy to achieve. Due to its excellent detection performance and easy preparation into polymer fiber materials, fluorescent sensor polymer materials have become the focus of researchers. However, due to the high concentration of fluorescent sensors, fluorescence quenching is easy to occur, which greatly reduces the detection sensitivity. How to maintain the sensi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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