Two-phase oil adjuvant foot-and-mouth disease vaccine stabilizer and application thereof

A foot-and-mouth disease vaccine and stabilizer technology, applied in the field of animal biological products, can solve the problems of reduced immune effect, undetectable antibodies, and demulsification, so as to reduce animal stress, ensure immunogenicity, and increase the proportion of water phase Effect
CN113893340APending Publication Date: 2022-01-07CHINA ANIMAL HUSBANDRY IND
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
CHINA ANIMAL HUSBANDRY IND
Publication Date
2022-01-07

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Abstract

The invention discloses a two-phase oil adjuvant foot-and-mouth disease vaccine stabilizer and application thereof The two-phase oil adjuvant foot-and-mouth disease vaccine stabilizer is prepared from the following components in percentage by weight of 0.1 to 1 percent of acid, 0.1 to 2 percent of alcohol, 0.1 to 2 percent of amine, 0.1 to 10 percent of charge control agent, 0.1 to 15 percent of polymer, 0.1 to 20 percent of sugar and the balance of water. The stabilizer provided by the invention improves the preservation effect, immune efficacy and safety level of the two-phase oil adjuvant foot-and-mouth disease vaccine.
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Description

Technical field

[0001] The present invention belongs to the technical field of animal biological products, and specific to stabilizers and their applications thereof are related to double-phase oil joined foot-and-mouth disease vaccine. Background technique

[0002] Foot-and-mouth disease is an acute, thermal, highly contactive infectious disease caused by the cow, pig, and sheep caused by foot and mouth disease virus, FMDV, which can reduce animal production performance, causing huge direct economy. Loss, was listed by OIE as the first place in 16 kinds of animal diseases. The foot-and-mouth disease virus belongs to small RNA virus, and there are seven serotypes of foot-and-mouth disease: A type, O type, C-type, SAT1 type, SAT2 type, SAT3 type, ASIA1, foot-and-mouth disease antigen immunogenic immunogenicity, antigen No crossover protection between various types. The prevention and control measures for foot-and-mouth disease are mainly immunized by immunization prevention, and e...

Claims

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