Tissue engineering cartilage based on placenta source filling dry cell and production thereof

Abstract

A tissue engineering cartilage based on placenta original filled stem cell and its production are disclosed. The process is carried out by using filled stem cell of placenta original as seed cell, combining with degradable porous biological material to construct tissue engineering cartilage. It is convenient and has short cell culture time and easy quality control, it can be used for functional repair of joint cartilage injure.

Description

field of invention

[0001] The invention relates to a tissue-engineered cartilage based on placenta-derived mesenchymal stem cells and a manufacturing method thereof, belonging to the field of tissue engineering. Background technique

[0002] Articular cartilage trauma repair is still a great challenge in clinical medicine. Current treatment options include cartilage or bone-cartilage grafts and artificial joints. Autologous cartilage is the best transplant material, but it is not ideal in terms of application because of the limited body size and the need for surgery at a second site to obtain sufficient cartilage tissue for transplantation. However, the replacement repair of artificial joints has so far been difficult to achieve functional repair effects, and is often accompanied by various complications. Despite many years of unremitting efforts in this field, there is still a need to find an effective treatment for the repair of articular cartilage damage, providing appr...