Medical material with heterogeneous coating and its preparing method

A non-homogeneous coating technology, which is applied in the fields of pharmaceutical formulation, medical science, dental preparations, etc., can solve the problems of long-term coating decline, high solubility, and insufficient activity, etc., to ensure long-term stability and bonding strength High, mineralization-promoting effect
CN1775305AInactive Publication Date: 2006-05-24ZHEJIANG UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
ZHEJIANG UNIV
Publication Date
2006-05-24
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention discloses a medical material with heterogeneous coating layer and its preparation method. It is composed of medical matrix and heterogeneous coating layer coated on the surface of said medical matrix, the described heterogeneous coating layer is formed by distributing zinc, magnesium or strontium contained calcium phosphate or calcium carbonate coacervate whose gain size is 200nm-20 microns into the calcium phosphate coating layer containing manganese and containing fluorine, in which the surface of calcium phosphate coating layer containing manganese or containing fluorine has high surface potential adsorption function, it is favorable for promoting adsorption of cell on its surface, the zinc, magnesium or strontium contained calcium phosphate or calcium carbonate coacervate has ion-releasing function, it can utilize the mode of releasing beneficial ions to promote cytogenic protein secretion and promote mineralization, etc.
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Description

technical field

[0001] The invention relates to a medical biological material, in particular to a medical material used for hard tissue repair, which has a heterogeneous coating composed of two micron-scale blocks with different functions on the surface and a preparation method thereof. Background technique

[0002] Since hard tissues such as bones and teeth are mostly located in the load-bearing parts, correspondingly, while considering whether the implant can produce good bonding with the living tissue, its mechanical properties are very important. However, it is difficult for a single material to meet the requirements of both mechanical properties and bioactive properties. At present, the method of coating a layer of active coating capable of depositing osteoid apatite on the surface of the medical metal substrate is mostly used. For example, the Chinese patent CN1064610 adopts a plasma spraying process to prepare a layer of hydroxyapatite coating on the dental metal sur...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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