Composite porous calcium phosphate bone cement and method for making same

Abstract

The invention relates to compound porous calcium orthophosphate skeleton cement. Wherein, said cement is formed by calcium orthophosphate skeleton cement powder, 3-hydroxy butanoic acid-CO-3-hydroxy pentanoic acid polymer microball, and solidify liquid. And the production comprises: preparing orthophosphate skeleton cement solid powder; preparing analogue humor; mixing the PHVV microball radiated by Co60 gama-ray; washing, drying and emerging it in the analogue humor, to be washed and dried; then mixing the PHBV microball and solid powder, to be added with solidify liquid to obtain the product. The invention has high strength, quick degradation and controllable degradation speed. And it can be used to repair skeleton hurt and used as skeleton support.

Description

technical field

[0001] The invention belongs to the technical field of calcium phosphate bone cement composite materials, in particular to a composite calcium phosphate bone cement composite material capable of degrading in vivo to form pores and a preparation method thereof. Background technique

[0002] Self-curing calcium phosphate bone cement has in-situ curing at room temperature or human physiological environment temperature, the structure and composition of the cured body are similar to the structure and composition of natural bone mineral phase, it can be shaped arbitrarily during surgery, and can fill bone defects of various shapes, etc. It can be widely used in clinical fields such as fracture fixation, bone defect repair, dental and maxillofacial surgery repair, and drug carrier. It is a research hotspot in the field of bone repair and hard tissue replacement materials.

[0003] Although the ordinary calcium phosphate bone cement material also has a certain porosi...