A device configured for use at a
catheter insertion site on a subject can include a base configured to be secured to the subject's
skin over the
insertion site and a
catheter hub holder configured to secure to a
catheter hub connected to a catheter that is configured for
insertion at the
insertion site. The
catheter hub holder can be movably coupled to the base to allow for relative movement between the base and the
catheter hub and catheter. The
catheter hub holder and base can be connected via a
gimbal arrangement. The base can include a membrane configured to secure to the subject's
skin and a frame. In some implementations, the catheter hub holder is rotatably coupled to a clamp that is connected to the frame. In some implementations, the clamp is pivotably connected to the frame and configured to pivot between open and closed positions.