A non-invasive method and device for promoting a localized change in a flow of blood through a
blood vessel in a
limb segment of a body by a series of electrically stimulated contractions of
muscle tissue in the
limb segment, the method including the steps of: (a) providing a device including: (i) first, second and third electrodes, each adapted to operatively contact the
limb segment; (ii) a
signal generator, operatively connected to the electrodes, adapted to produce a series of electrical impulses to the limb segment via the electrodes, and (iii) a
control unit adapted to control the
signal generator to produce the series of electrical impulses; (b) positioning the electrodes on the limb segment, wherein the first
electrode is positioned on a lower end of the lower leg, the second
electrode is positioned on the lower leg, and the third
electrode is positioned on an upper end of the lower leg, whereby the first and third electrodes are disposed on opposite ends of the lower leg, and the second electrode and one of the first and third electrodes are disposed on a same end of the lower leg; (c) effecting a sequence of
muscular contractions of the lower leg, by operations including: (i) applying a first
electrical impulse between the electrodes on the same end of the lower leg to induce a first muscular contraction of a first portion of the tissue; and (ii) applying at least a second
electrical impulse between the first and third electrodes to induce a longitudinal muscular contraction of a second portion of the muscular tissue; and (d) repeating operations (i) and (ii), to repeatedly induce the contractions, to effect the increased flow of blood.