The invention discloses a medical medicinal material grinding device with noise reduction function, which comprises a base, a piston cylinder, a piston ball, a shear thickening liquid, a grinding box, a driving motor, a runner, a feeding device, a grinding motor, a grinding wheel and Material receiving device, the inside of the piston cylinder is filled with shear thickening liquid; several groups of elastic steel plates are fixedly installed on the left and right sides of the support seat. The upper end of the elastic steel plate is rotated by a bearing to install a pulley, and the pulley is slidably installed inside the slide rail; A feeding device is connected to the lower side of the feeding port. According to the change of the descending speed of the piston ball, the shear thickening fluid can produce different resistances to improve the shock absorption effect of the device when it is working. The two sides move to press the elastic steel plate downward to play the role of shock absorption and buffering. Through the joint action of the above two kinds of shock absorption and buffering, the noise generated during the grinding process can be effectively reduced.