Synthetic peptide and application thereof

A technique for synthesizing peptides and wound healing agents, applied in the field of biology, can solve the problems of natural antibacterial peptide content, activity, activity-dependent structure, production cost, etc., achieve significant wound healing effect, realize the effect of low dosage of production and use
CN102816206BInactive Publication Date: 2014-07-23CHONGQING ACAD OF ANIMAL SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
CHONGQING ACAD OF ANIMAL SCI
Publication Date
2014-07-23
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to the technical field of biology, in particular to a synthetic peptide containing an amino acid sequence shown as SEQ ID NO: 1. The invention also relates to application of the synthetic peptide in preparation of anti-infective drugs and wound healing drugs. The synthetic peptide is a hexapeptide formed by only six amino acids and is synthesized by a chemical method, so the production cost is reduced accordingly; compared with other complicated antibacterial peptides or growth factor peptide preparations and the like, the synthetic peptide is easier to produce and is suitable for being widely used in clinic; and the synthetic peptide provided by the invention has multiple activities, high antibacterial activity, a significant role in promoting wound healing, low dose, one-time daily application and obvious efficacies.
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Description

technical field

[0001] The invention relates to the field of biotechnology, in particular to synthetic polypeptides and applications thereof. Background technique

[0002] Since the invention of antibiotics, human beings have made great achievements in the control and treatment of microbial infections, but with the continuous use of antibiotics, microbial resistance has become a major problem in infection control, so that some microbial bacteria have no control kill. first-line drug. As in clinical drug therapy, vancomycin-resistant staphylococci. Enterococcus and other Gram-negative bacterial infections are currently clinical problems worldwide.

[0003] Antimicrobial peptides are small-molecule polypeptide substances with broad-spectrum antibacterial activity, effective on prokaryotes, and harmless to eukaryotes. Antimicrobial peptides are a class of peptides produced in the biological defense system against exogenous pathogens, and are an important part of biological i...

Claims

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