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Gelan Xinning soft capsule for treating coronary disease and angina and preparation method thereof

A coronary heart disease angina pectoris and gelatin technology, which is applied in the treatment of coronary heart disease angina pectoris Gelanxinning soft capsules and its preparation field, can solve the problems of complex preparation methods of the raw material kudzu root total flavonoids, long production cycle, and small breakthrough in therapeutic effect, etc. Achieve significant clinical therapeutic economic significance, short production cycle, no toxic and side effects

Active Publication Date: 2013-01-16
XIAN CHIHO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Chinese patent ZL03134404.6 with the title of "a drug for treating coronary heart disease and angina pectoris and its preparation method" discloses a drug for treating coronary heart disease and angina pectoris. The preparation method of total flavonoids is complex and the production cycle is long

Method used

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  • Gelan Xinning soft capsule for treating coronary disease and angina and preparation method thereof
  • Gelan Xinning soft capsule for treating coronary disease and angina and preparation method thereof
  • Gelan Xinning soft capsule for treating coronary disease and angina and preparation method thereof

Examples

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Effect test

Embodiment 1

[0046] A kind of Chinese patent medicine for treating angina pectoris of coronary heart disease. 1 part of hydrogenated palm oil, 0.2 part of soybean lecithin, 0.01 part of simethicone, 8 parts of gelatin, 3 parts of glycerin, 8 parts of purified water and 0.01 part of ethyl paraben.

[0047] The preparation method of this Chinese patent medicine comprises the following steps:

[0048] (1) Preparation of kudzu root total flavonoids:

[0049] Take Pueraria mirifica, break it into coarse powder, soak it with 60% ethanol aqueous solution for 1 hour, and then reflux for extraction twice, each time with 8 times the weight of the drug, reflux for 2 hours each time, combine the two extracts, Filtrate, concentrate under reduced pressure to an extract with a relative density of 1.16 (60°C heat test), spray dry, grind through a 80-mesh sieve, and obtain the total flavonoids of kudzu root;

[0050] (2) Preparation of hawthorn extract:

[0051] Take hawthorn slices, and use 80% ethanol...

Embodiment 2

[0058] A kind of Chinese patent medicine for treating coronary heart disease and angina pectoris. 0.6 parts of hydrogenated palm oil, 0.4 parts of soybean lecithin, 0.02 parts of simethicone, 12 parts of gelatin, 5 parts of glycerin, 10 parts of purified water and 0.02 parts of ethylparaben.

[0059] The preparation method of this Chinese patent medicine comprises the following steps:

[0060] (1) Preparation of kudzu root total flavonoids:

[0061] Take Pueraria mirifica, break it into coarse powder, soak it with 65% ethanol aqueous solution for 1 hour, and then reflux for extraction twice, each time with a solvent 6 times the weight of the drug, and reflux for 1.5 hours each time, combine the two extracts, Filtrate, concentrate under reduced pressure to an extract with a relative density of 1.28 (60°C heat test), then vacuum-dry, crush and pass through an 80-mesh sieve to obtain the total flavonoids of kudzu root;

[0062] (2) Preparation of hawthorn extract:

[0063] Tak...

Embodiment 3

[0070] A kind of Chinese patent medicine for treating coronary heart disease and angina pectoris. 1 part of hydrogenated palm oil, 0.6 part of soybean lecithin, 0.03 part of simethicone, 25 parts of gelatin, 8 parts of glycerin, 20 parts of purified water and 0.04 part of ethylparaben.

[0071] The preparation method of this Chinese patent medicine comprises the following steps:

[0072] (1) Preparation of Pueraria total flavonoids:

[0073] Take Pueraria mirifica, break it into coarse powder, infiltrate with 75% ethanol aqueous solution for 1 hour, and then reflux for extraction twice, each time with 7 times the amount of drug weight solvent, reflux for 2.5 hours each time, combine the two extracts, Filtrate, concentrate under reduced pressure to an extract with a relative density of 1.25 (thermally measured at 60°C), spray-dry, and crush through a 80-mesh sieve to obtain the total flavonoids of kudzu root;

[0074] (2) Preparation of hawthorn extract:

[0075] Take hawtho...

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Abstract

The invention provides a Gelan Xinning soft capsule for treating coronary disease and angina and a preparation method of the Gelan Xinning soft capsule. The medicine comprises the following raw materials in parts by weight or is composed of the following raw materials in parts by weight: 4 to 60 parts of radix puerariae general flavones, 1 to 30 parts of fructus crataegi extract, 0.4 to 10 parts of gynostemma pentaphylla general flavones, 5 to 100 parts of soybean oil or salad oil, 0.1 to 3 parts of beewax, 0.4 to 10 parts of hydrogenated palm oil, 0.2 to 5 parts of soyabean lecithin, 0.01 to 0.5 parts of dimeticone, 8 to 150 parts of gelatin, 3 to 80 parts of glycerol, 8 to 150 parts of purified water and 0.01 to 0.8 parts of ethylparaben. The preparation method of the medicine provided by the invention is simple, the processing cost is low, the efficacy is remarkable and the Gelan Xinning soft capsule is free from any toxic and side effects.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and relates to a medicine for treating angina pectoris of coronary heart disease and a preparation method thereof, in particular to a Gelanxinning soft capsule for treating angina pectoris of coronary heart disease and a preparation method thereof. Background technique [0002] Coronary heart disease is caused by coronary artery atherosclerosis and coronary artery stenosis, which leads to myocardial blood supply disorder. Because the myocardium is in a long-term ischemia-hypoxic state, it will inevitably lead to myocardial cell degeneration, atrophy, and myocardial damage. After the disease develops seriously, it can lead to heart failure. etc., directly endangering human life. With the improvement of people's living standards, the morbidity and mortality of coronary heart disease in my country are also increasing year by year, and there is a trend of younger patients. Angina pectori...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/734A61K36/488A61K9/48A61P9/10A61P9/12A61P3/06
CPCA61K36/48A61K36/488A61K36/734A61K9/107A61K31/80A61K36/889A61K31/685A61P3/06A61P9/10A61P9/12A61K2300/00
Inventor 胡小虎赵宗平
Owner XIAN CHIHO PHARMA
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