Locating quick-release biological adhesive and application thereof

Abstract

The invention provides locating quick-release biological adhesive and relates to a medical device for preventing or / and treating diabetes, adiposis, alcoholism, gastric and intestinal mucositis or / and ulcer and the like. According to the locating quick-release biological adhesive, biocompatible biological adhesion materials are prepared into particles, a quick-release disintegrating agent is added, the particles are coated with enteric or gastric-soluble coatings after being tableted, or the particles are coated with the enteric or gastric-soluble coatings, or the particles are filled in enteric or gastric-soluble hollow capsules, or additives such as the biological adhesion materials and the quick-release disintegrating agent are directly tableted and then coated with the enteric or gastric-soluble coatings; after the locating quick-release biological adhesive is taken, the locating quick-release biological adhesive is located and quickly released, is rapidly adhered to and covers upper sections of a duodenum and a jejunum or / and a gastric mucosa, and weakens absorption of the upper sections of the duodenum and the jejunum or / and a stomach; the locating quick-release biological adhesive is taken orally, and convenient to carry, store and use, a user does not need to go hospital or undergo a surgery or endoscopy, and has no pain; the compliance of the user is improved; and operational repeatability is avoided.

Description

technical field [0001] The invention relates to a biocompatible medical device for internal or / and external use, in particular to a localized immediate-release biological device for preventing or / and treating diabetes, obesity, alcoholism, gastric and intestinal mucosal inflammation or / and ulcers, etc. Adhesives. Background technique [0002] In March 2011, at the Second International Conference on Interventional Treatment of Type 2 Diabetes held in New York, USA, the International Diabetes Federation (IDF) stated for the first time that gastric bypass surgery can be used to treat obese type 2 diabetes patients and reduce chronic complications of diabetes. The occurrence and development of the disease (Chinese Medical Science, 2011,1(22):1-2). This kind of operation can also significantly improve the complications of patients such as hypertension, obesity, and blood lipid disorder (Chinese Medical Science, 2011, 1(21):3-5). However, gastric bypass surgery has clinical risk...

AI Technical Summary

Problems solved by technology

[0004] Common hangover thinking, how to passively release or reduce its effect after drinking, the corresponding prior art invention patent "a prescription and preparation process of oral medicine for hangover" (application date December 20, 2010 , published on July 11, 2012), the invention patent of the prior art "an anti-drunk hangover composition and its preparation method" (application date May 18, 2012, publication date September 19, 2012) , the invention patent of the prior art "oral absorption solid hangover effervescent preparation" (application date July 12, 2010, publication date December 22, 2010), etc., and does not evaluate the effect of these substances on hangover relief, its Through absorption, metabolism and other in vivo pathways, it will also increase the burden on organs such as the liver and / or kidneys. More importantly, the node of passive hangover is basically after the body absorbs alcohol, which has increased the burden on the body's related organs.

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