Full-nutritional formula food for nephropathy

Abstract

The invention provides a full-nutritional formula food, a specific full-nutritional formula food or a non-full-nutritional formula food for patients with nephropathy. The formula is based on the requirements of general principles of formula food with special medical use, is combined with the constitutive characters of the patients with nephropathy, is integrated with the advanced research results of physiology, medicine, nutriology, clinical application and the like of Harvard University at present, and is developed according to the traditional Chinese medicine essence theory (with the main principle of homology of three internal organs including liver, spleen and kidney) of'reinforcing middle energizer to reside the dispelling Qi' and'balancing aftercare'. The product takes more than ten medicine and food dual-purpose traditional Chinese medicine extract essences, multiple probiotic bacteria and prebiotics as main raw materials, and takes oligopeptides, amino acid, water-soluble dietary fiber, multi-vitamins and composite minerals as auxiliary materials, thus not only being used as a single nutrition source to meet the demand for nutrition of the patients with nephropathy, but also having the effects of invigorating the kidney and strengthening Yang, replenishing the vital essence and enriching the blood, nourishing the liver and the kidney, strengthening tendons and bones, securing essence and reducing urination and controlling the nephropathy.

Description

technical field [0001] The invention belongs to the technical field of medicine and food homologous formula and food, and specifically combines the traditional Chinese medicine essence theory of "medicine and food homologous Chinese medicine" with "multiple probiotics", and adds short peptides, prebiotics, amino acids, Water-soluble dietary fiber, multi-vitamins, and multi-mineral supplements are complete nutritional formula foods for the prevention and treatment of kidney disease, specific complete nutritional formula foods or non-complete nutritional formula foods. Background technique [0002] Definition of Chronic Kidney Disease (CKD): Chronic kidney structure and dysfunction caused by various reasons (history of kidney damage for more than 3 months), including pathological damage with normal and abnormal renal GFR, abnormal blood or urine components, and imaging studies Abnormal examination, or unexplained decrease in GFR (<60ml / min · 1.73m 2 ) for more than 3 month...

AI Technical Summary

Problems solved by technology

[0005]The relationship between gut microbiome and kidney disease: Studies have shown that Enterobacteriaceae, Halomonasceae, Halomonasceae, The 190 taxonomic operating units (OTUs) clustered by Moraxellaceae and other sequences are significantly different from healthy people. Patients with end-stage renal disease have damage to the structure and function of the intestinal mucosal barrier. and immune response affect the systemic inflammatory response of such patients, and the toxic damage of some metabolites to the kidney may also be related to the intestinal flora. Studies have shown that in rats treated with melamine, antibiotics inhibit intestinal flora After group activity, the excretion of melamine was accelerated, and the toxic reaction induced by it was weakened. Further in vitro studies showed that Klebsiella can directly convert melamine into cyanuric acid. Rats that received Klebsiella transplantation showed that melamine The induced nephrotoxicity was exacerbated, and the content of cyanuric acid was found to be increased in the kidney, suggesting that the gut microbiota may mediate the nephrotoxicity caused by melamine

[0006] For kidney disease, direct oral administration of probiotics has a certain effect, but since probiotics cannot colonize in the intestinal tract, and stay and occupy very little space, they are easy to be lost. Harmful bacteria are easy to relapse after taking it, and the relevant patients need to take it for a long time, and the treatment cycle is long, and the recurrence rate after use is often very high; Key technical research on the mechanism of intestinal colonization, and strive to improve the "medicine and food homologous traditional Chinese medicine" compound formula for improving the colonization of probiotics in the intestinal tract, taking into account several key elements of the colonization of probiotics in the intestinal tract: the presence of prebiotics can play a role Based on the above elements, the research group screened suitable ingredients from dozens of "Chinese medicines with the same source of medicine and food", and discovered for the first time After adding extracts of traditional Chinese medicine ingredients such as yam, barley, gallinacea, Gorgon fruit and Jerusalem artichoke, as well as stachyose, yeast, L-glutamine, etc., it has a strong colonization effect on exogenous probiotics. Provide experimental basis for the selection of probiotics in intestinal microecological preparations

[0007] At present, there are food-derived short peptides used as the main raw material in the market, and the extracts of shiitake mushrooms, tangerine peel, wolfberry, yam, poria cocos, and sealwort for both medicine and food are added. , multivitamins and minerals to form a compound formula, and there are products using probiotics as the main raw material, but it has not been found to combine the physical characteristics of patients with liver disease. According to the essence theory of traditional Chinese medicine, it varies from person to person. The golden compatibility is based on ten kinds The above medicinal and edible Chinese medicine extract essence, a variety of probiotics, and prebiotics are the main raw materials, and the complete nutritional formula food made of short peptides, amino acids, water-soluble dietary fiber, multivitamins, and composite minerals. Nutritional formula or similar product