Leontopodium alpinum toothpaste and preparation method thereof

Abstract

The invention relates to the technical field of oral cavity cleaning supplies, in particular to leontopodium alpinum toothpaste. The leontopodium alpinum toothpaste comprises the following raw materials in percentage by weight: 20-30% of calcium hydrophosphate dihydrate, 28-42% of a humectant, 8-12% of calcium hydrophosphate, 8-14% of hydrated silica, 2-3% of a foaming agent, 1-1.5% of essence, 0.8-1.6% of an adhesive, 0.2-0.8% of tetrasodium pyrophosphate, 0.2-0.5% of a sweetening agent, 0.2-0.5% of a preservative, 0.1-0.5% of a leontopodium alpinum extract, 0.05-0.2% of lysozyme, 0.05-0.2% of tranexamic acid, 0.84-1.5% of glycyrrhizin and 5.45-12.35% of purified water. The leontopodium alpinum toothpaste prepared by the method is natural, safe, free of side effects, not easy to generatedrug resistance, capable of increasing the pain threshold of a mouse, remarkable in analgesic effect and capable of effectively preventing and relieving toothache, and the leontopodium alpinum toothpaste is not easy to delaminate, proper in viscosity, not easy to be influenced by temperature, easy to extrude and relatively good in stability.

Description

technical field [0001] The invention relates to the technical field of oral cleaning products, in particular to an edelweiss toothpaste and a preparation method thereof. Background technique [0002] Toothache is one of the common clinical symptoms of stomatology. It is caused by diseases of the teeth themselves, periodontal tissue diseases, and adjacent tissue diseases of the teeth. Zhou Yan and other diseases related. In terms of treatment, western medicine adopts anti-inflammatory and pain relief, but it is more likely to recur; and according to the theory of traditional Chinese medicine, toothache can be divided into stomach heat type: symptoms include severe tooth pain, red and swollen gums, pain in the maxillofacial area, headache, thirst and bad breath , constipation, red tongue with yellow coating, slippery and rapid pulse; wind-fire type: symptoms include toothache, red, swollen and painful gums, pain relieved by cold, severe pain by wind or heat, or fever, aversio...

AI Technical Summary

Problems solved by technology

[0005] Chinese patent application CN110038073A discloses a composition for treating oral diseases, which uses active extracts of edelweiss, blue cloth, honeysuckle, emblica, and grape seed as active ingredients, which have the effect of clearing away heat and detoxification. The composition can be used It is used for the treatment of diseases such as caries, bleeding gums, swelling and pain of the mouth or gums, oral inflammation, oral ulcers, gingivitis or periodontitis, but the active extract in the composition is extracted by ethanol soaking and low addition number fatty alcohol solvent Get the powder, and then mix the powder with an acceptable carrier. After long-term use, the composition is prone to drug resistance, and cannot effectively relieve pain and toothache

[0006] Lysozyme is a hydrolytic enzyme that specifically acts on the cell wall of microorganisms. Adding lysozyme to toothpaste makes the antibacterial effect of toothpaste better. However, in the actual production of toothpaste, lysozyme is often unstable under alkaline conditions. Easy to inactivate, resulting in easy layering of the paste, therefore, there is still room for improvement

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