4 results about "Angina pain" patented technology

The present invention is related to methods of treating cardiac arrhythmia, angina, or a migraine in a patient in need thereof, with a therapeutically effective amount of a compound having a structure according to the formula:the method comprising nasally administering to the patient (i) a first dose, and (ii) a second dose of an aqueous composition comprising a pharmaceutically acceptable acetate or methanesulfonate salt of compound I, or a racemate or enantiomer thereof, wherein the acetate or methanesulfonate salt of compound I, or the racemate or enantiomer thereof, is dissolved in the aqueous composition at a concentration of 350 mg / mL±50 mg / mL, and wherein the second dose of the compound is administered between 5 minutes and 25 minutes after the first dose.

The invention provides a composition, a traditional Chinese medicine composition and application thereof. Specifically, the invention provides a composition which comprises coix seeds, radix aconiti carmichaeli and musk. The composition can prevent and treat coronary heart disease angina pectoris, improve the attack frequency of angina pectoris, relieve the symptoms of chest distress and pain when angina pectoris attacks, and improve the long-term prognosis effect and life quality.

The application discloses a composition of Qixuebengzhi recipe and belongs to the field of traditional Chinese medicines; the composition is mainly prepared from bupleurum, immature fruit of citrus, persicae semen, safflower, chuanxiong and red peony root; the application is based on the concept of treating heart and body simultaneously, and through the ascending and descending of qi and the regulating of liver qi of bupleurum and immature fruit of citrus, the composition can dredge the liver and regulate qi, and through the dispersing of persicae semen and safflower, the composition can dredge the channels and remove stasis, and through the combination of chuanxiong and red peony root, the composition can regulate qi and blood, and the combination of the medicines can directly attack the core pathogenesis of qi stagnation and blood stasis; clinical verification shows that the composition can not only significantly improve the TCM syndromes such as chest pain and chest distress of patients and the frequency of angina pectoris attacks, but also quickly relieve anxiety and depression and improve sleep quality.

The present disclosure relates to compositions and methods, including prodrugs of (S)-3-(3-(((3,4- dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H- benzo[d]azepin-2-one that find use in the treatment of diseases and disorders, such as therapies for cardiovascular disease, including cardiac arrhythmias, including, without limitations, sinus tach (e.g. inappropriate sinus tachycardia (IST)), postural orthostatic tachycardia syndrome (POTS), coronavirus (COVID-19) (e.g. long COVID) and COVID-associated cardiovascular abnormalities, supraventricular tachycardia (SVT), tachycardia (e.g. rapid heart rate, atrial tachycardia), heart failure (e.g. congestive heart failure (CHF), systolic heart failure, pediatric heart failure, chronic heart failure), myocardial ischaemia, angina (e.g. angina pectoris), myocardial infarct, rhythm disturbances (e.g. supraventricular rhythm disturbances), chest pain, cardiomyopathy, coronary artery disease, and left ventricular dysfunction (LVD).