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62 results about "Bladder volume" patented technology

The entire volume of the bladder varies but it can hold between 400 mL to 1000 mL. The ureters will be opening into the body of the bladder posteriorly and you see here the orifices where they are going to be connecting with the bladder and we will talk about them later on on this tutorial.

Instantaneous ultrasonic measurement of bladder volume

An apparatus and methods to quantify the volume of urine in a human bladder with a limited number of acoustic beams is disclosed. In a first version the apparatus is composed of a transducers assembly that transmits a plurality of narrow ultrasound beams in different directions towards the bladder and receives the returning ultrasound signals; a receiver detector for processing the returned signals; an analog-to-digital converter; a memory to store the digitized data and a volume display allowing to define the optimal position of the transducer assembly. The apparatus also includes a signal processing software that automatically determines the bladder Depth D and Height H and computes the volume of urine using an empirical formula corrected by specific, empirically measured, filling dependant correction factors. In a second version a single wide angle ultrasound beam transducer transmitting ultrasound signals at fundamental frequency is used to quantify the urine volume. Return signals originating from a depth beyond the usual position of the posterior wall depth of a filled bladder are analyzed for presence of higher harmonic signals which in turn are related to presence or absence of urine. Both methods or a combination thereof can be used us a simple warning device for presence of residual urine after voiding or indicate the presence of a critical bladder urine filling level.
Owner:VERATHON

Implantable bladder sensor

An implantable sensor for monitoring the condition of an organ, such as the bladder, of a recipients' body. The sensor (100) comprises a carrier (102), such as a tubular housing that is attachable to the outer surface of the organ. An impedance-varying means (104), such as a saline solution, is carried by the carrier (102). The impedance-varying means (104) within the carrier varies as the condition of the organ changes to cause in output state of the sensor (100). The sensor (1000) can be used for the purposes of monitoring the filling of the bladder, making bladder volume information to the recipient or another person, and causing an alarm signal to be generated when a preset bladder volume is reached.
Owner:NEOPRAXIS

Pessary Device

A pessary comprising a main stem and an inflatable bladder disposed about the proximal larger diameter section of the main stem. The main stem further comprises a distal smaller diameter portion having a cap at its distal tip and a check valve disposed there under. The check valve communicates with a central fluid passage that may extend into the proximal larger diameter section of the main stem. Secondary fluid passages connect the central fluid passage to the inflatable bladder volume disposed about the outer circumference of the proximal larger diameter section of the main stem. The main stem provides support to the pelvic structures and the inflatable bladder acts to hold the device in position. At least one void through the proximal larger diameter portion of the main stem allows bodily material to pass from the vagina through the pessary device thereby decreasing the amount of vaginal discharge.
Owner:ZIPPER RALPH

A method and system for automatic measurement of bladder volume in ultrasound images

ActiveCN102274051AAutomatic volume estimationReduce repetitive and boring workOrgan movement/changes detectionUltrasonic/sonic/infrasonic dianostic techniquesRadiologyDiagnostic ultrasound
The invention relates to a method and system for automatically measuring the bladder volume of an ultrasonic image. The method for measuring the bladder volume comprises the following steps of: acquiring an ultrasonic image; acquiring an ultrasonic bladder image through ultrasonic scanning; preprocessing the ultrasonic image; preprocessing the acquired ultrasonic bladder image; acquiring a bladder pixel contour line through the gray level difference between the ultrasonic bladder image and peripheral ultrasonic non-bladder images; selecting radial line measured values: analyzing the acquired bladder pixel contour line and selecting a first radial line measured value and a second radial line measured value; and the measuring the bladder volume according to the selected first radial line measured value and the selected second radial line measured value. According to the method for measuring the bladder volume of the ultrasonic image, the measuring result is more accurate, and the measuring precision is improved; meanwhile the repeated and dried works of a user can be reduced, and the efficiency of an ultrasonic diagnosis system is improved; and the method disclosed by the invention is more convenient and rapid to use.
Owner:EDAN INSTR

Instantaneous ultrasonic echo measurement of bladder volume with a limited number of ultrasound beams

An apparatus and methods to quantify the volume of urine in a human bladder with a limited number of acoustic beams is disclosed. In a first version a plurality of narrow ultrasound beams is transmitted in different directions towards the bladder. Returning echoes are converted to digital form and stored in memory. A volume display on the apparatus allows to define the optimal apposition of the transducer assembly. Signal processing software automatically determines the bladder Depth D and Height H and computes the volume of urine. In a second version, a single wide angle ultrasound beam transducer transmits ultrasounds signals at a fundamental frequency to quantify the urine volume. Return signals originating from a depth beyond the usual position of the posterior wall depth of a filled bladder are analyzed for presence of higher harmonic signals, which in turn are related to the presence or absence of urine.
Owner:VERATHON

Simulation and analysis device for physiological processes of urine storage and emiction of bladder

InactiveCN101664313AAccurately monitor complianceAccurately monitor urine flow rateEducational modelsUrological function evaluationPerfusionPelvic cavity
The invention provides a simulation and analysis device for physiological processes of urine storage and emiction of the bladder, comprising an artificial bladder, an artificial urethra, a pelvic cavity sink, an extrusion device, a pressure device, a perfusion device, a urine recovery device, a pressure measuring device and a flow metering device. The artificial bladder is used for simulating thefeature that the bladder changes volume along with the liquid capacity and realizing the function of urine storage; the artificial urethra used as a channel for discharging liquid in the bladder; thepelvic cavity sink is used as the environment for containing organs of the bladder, and the like; the extrusion device is used for simulating extrusion caused by the peripheral organs of the bladder to the bladder; the pressure device is used for simulating the shrinkage of detrusor of the bladder so as to realize the function of emiction of the bladder; the perfusion device is used for accuratelymeasuring and displaying the liquid amount perfused to the bladder in real time; the urine recovery device is used as liquid reserve of liquid pumping of the perfusion device and for collecting the liquid discharged from the urethra so as to facilitate recycling; the pressure measuring device is used for measuring and displaying inner pressure of the bladder and the inner pressure of a pelvic cavity in real time; and the flow metering device is used for measuring and displaying the flow of the liquid passing through the urethra in real time. The invention can realize the physiological processes of urine storage and emiction of the artificial bladder, analyzes the physiological process by controlling and monitoring urine dynamical parameters of bladder volume.
Owner:BEIHANG UNIV

Sensor for measuring bladder volume, and system and method of managing bladder using the same

The invention relates to a sensor for measuring bladder volume that includes an RFID chip (particularly, a passive RFID chip) to generate driving power using an electric wave generated by a reader, and to transmit information on the measured bladder volume to the reader using an elastic wave or an electromagnetic wave, and to a system and method of managing a bladder using the same.A sensor for measuring bladder volume according to an embodiment of the invention includes an antenna that receives an electric wave, a transducer generates a predetermined wave and measures the bladder volume indicating the size of a bladder using the predetermined wave, and an RFID chip that generates and supplies power using the electric wave received by the antenna, generates information on the bladder volume from the measured bladder volume, and transmits the generated information to the outside through the antenna. The sensor for measuring bladder volume is attached to the skin in an abdominal region of a user.According to the embodiment of the invention, since the sensor for measuring bladder volume does not use a battery, it is reduced in size, thereby improving mobility. Therefore, an adverse affect when the sensor is inserted into the body through a surgical operation can be prevented.
Owner:GWANGJU INST OF SCI & TECH

Method of urinary continence training based on an objective measurement of the bladder

Method of urinary continence training, utilizing an objective measurement, indicative of the state of fullness of the bladder of the subject, to identify the occurrence of an appropriate continence training opportunity. When the objective measurement equals or exceeds a signal threshold value, set to correspond to a bladder volume that is less than a reflexive urination volume, a signal is provided to the subject or to a caregiver. The objective measurement may be performed by a bladder monitor, using any of several modalities of automatic sensing, and preferably using ultrasound. The signal threshold value may be recalculated and increased, so as to continue to correspond to a relatively full bladder, as the subject grows and / or achieves progress toward continence. The method may include other steps directed to help the subject associate the physical sensation of a full bladder with voluntary urination, such as informing the subject that urination is imminent.
Owner:THE PROCTER & GAMBLE COMPANY

Subsea fluid storage system

The present disclosure relates, according to some embodiments, to subsea fluid storage systems that may automatically and / or continuously compensate for subsea pressure changes. A subsea fluid storage unit with passive pressure compensation may comprise a vessel and a deformable bladder disposed within the vessel. A vessel may comprise a top port, a bottom port, and an internal vessel volume. A deformable bladder may comprise a first end and a second end. A second end may comprise a bladder opening that may be fluidically connected to a top port or a bottom port of a vessel. A deformable bladder may define an internal bladder volume that may be suitable for storage of fluids and / or chemicals.
Owner:OCEANEERING INTERNATIONAL

Device for measuring urine volume and pressure intensity of bladder and measurement and control method thereof

The invention provides a device for measuring the urine volume and the pressure intensity of a bladder and a measurement and control method thereof. Each pipeline is controlled to be on and off, a control and information analysis system records the corresponding value of the increment or decrement of the bladder pressure intensity and the bladder volume on each time point in real time in the irrigation process and the urination process; then, the information is collected and counted by the control and information analysis system to obtain and store the corresponding relationship of the bladder pressure intensity and the bladder volume as well as a graph and a report. The device for measuring the urine volume and the pressure intensity of the bladder has the advantages of convenience in operation and control, low cross infection risk and small potential safety hazard.
Owner:MIANYANG MEIKE ELECTRONICS EQUIP

Inflatable artificial muscle for elongated instrument

An inflatable artificial muscle for manipulating a flexible elongated instrument such as a medical endoscope that advantageously utilizes fluid pressure to facilitate insertion into a tortuous passage and maneuver of the instrument is described herein. The inflatable artificial muscle comprises a hollow cylinder-like bladder with a lumen or a plurality of such bladders joined end to end for receiving an elongated instrument. The bladder volume is divided into a plurality of chambers of varying configurations, which are in fluid communications with one another. There is provided a plurality of supply tubes for supplying and evacuating a pressurizing fluid to and from the bladder. The inflatable artificial muscle is activated by inflating the bladder with a pressurizing fluid to a predetermined internal pressure. The artificial muscle of the present invention is capable of straightening a portion of an elongated instrument in a bent configuration, which is enclosed within the lumen thereof.
Owner:CHUL HI PARK

Method and device for measuring bladder volume through ultrasound images

The invention discloses a deformable model-based method and device for measuring bladder volume through ultrasound images. The method for measuring the bladder volume through ultrasound images includes that acquiring n ultrasound images of a bladder; orderly arraying the n ultrasound images of the bladder according to the acquisition sequence, and constructing three-dimensional data of the bladder according to space information of the bladder; using a deformable model corresponding to the current form of the bladder to carry out three-dimensional image segmentation on the three-dimensional data of the bladder to obtain the bladder region; calculating the volume of the bladder region. The deformable model-based method and device for measuring the bladder volume through ultrasound images fully consider the shape difference of the bladder under different states, enable the bladder volume measurement result to be closer to the clinical manifestation of the bladder, enable the bladder volume measurement precision to be improved, and provide more precise reference data for diagnosing and treating bladder diseases.
Owner:深圳市大深生物医学工程转化研究院

Method and an apparatus for recording bladder volume

A non-invasive method and apparatus for monitoring the bladder volume in humans or animals. The monitoring measurements are based on the analysis of ultrasound signals from at least two individual ultrasound transducer arrays. Each one individual ultrasound transducer array has a contact face, which is arranged in order to transmit an ultrasonic signal through an abdominal surface of an individual being monitored. The method and apparatus includes the arranging of each individual transducer array on the abdominal surface around an axis which extends from a point on the abdominal surface through a point on or within the urinary bladder. The method and apparatus further comprises that each individual transducer array is arranged to scan the bladder using a two-dimensional scan plane which extends radially from the transducer array through the bladder.
Owner:URODAN

Bladder ultrasonic image segmentation method and device based on UNet convolutional neural network

The invention provides a bladder ultrasonic image segmentation method and device based on a UNet convolutional neural network, and the method comprises the steps: obtaining a bladder ultrasonic imageof a human body through ultrasonic scanning equipment; constructing a training set and a test set of the bladder ultrasonic images, wherein the training set and the test set comprise all bladder ultrasonic image data subjected to labeling and data enhancement processing; constructing a UNet convolutional neural network model, wherein the UNet convolutional neural network model comprises a lower sampling layer and an upper sampling layer; training the constructed UNet network model by using the training set image data of the bladder ultrasonic image to generate a network model, and testing themodel effect by using the test set image data of the bladder ultrasonic image; and segmenting the actual bladder ultrasonic image acquired by the ultrasonic equipment by using the trained UNet networkmodel. According to the invention, the interference of noise on bladder ultrasonic image segmentation can be eliminated, and the accuracy of bladder volume calculation is improved.
Owner:深圳市嘉骏实业有限公司

Bladder volume measuring device, and implementation method of the same

ActiveCN106562794AConvenient quantitative measurementPrecision radiotherapyUltrasonic/sonic/infrasonic diagnosticsInfrasonic diagnosticsImaging processingUltrasonic imaging
The invention relates to an implementation method of bladder volume measurement. The implementation method of bladder volume measurement includes the steps: control of a whole machine; control of probe scanning; control of emission and reception of ultrasonic signals; control of image processing and ultrasonic imaging; according to the obtained image information, drawing the boundary two dimensional coordinates of a plurality of bladder sections, converting the two dimensional coordinates of all the boundary points of each section into three dimensional coordinates, and enabling the three dimensional coordinates to employ OpenGL to establish a 3D bladder model; equally dividing the 3D bladder model into n layers from top to bottom, wherein n is the ultrasonic depth of the bladder; and calculating the area of each layer, and accumulating the areas to obtain the volume of the bladder. The invention also relates to a ladder volume measuring device. The bladder volume measuring device, and the implementation method of the same can conveniently measure the bladder volume without pain, thus reducing iatrogenic urinary system infection, reducing the pain caused by frequent conduit insertion and being convenient to operate, and can preferably control filling of bladder for pelvic cavity tumour radiotherapy, thus positioning accurately for pelvic cavity tumour radiotherapy and achieving accurate radiotherapy effect.
Owner:重庆康超医疗科技股份有限公司

Shape feature-based ultrasonic image bladder volume measuring method and device

The invention discloses a shape feature-based ultrasonic image bladder volume measuring method and device. The shape feature-based ultrasonic image bladder volume measuring method comprises the following steps: acquiring a two-dimensional bladder ultrasonic image; recognizing the shape of a bladder according to the two-dimensional bladder ultrasonic image; measuring the volume of the bladder according to the shape of the bladder. The shape feature-based ultrasonic image bladder volume measuring device comprises a two-dimensional bladder ultrasonic image acqusition unit for acquiring the two-dimensional bladder ultrasonic image, a bladder shape recognition unit for recognizing the shape of a bladder according to the two-dimensional bladder ultrasonic image and a bladder volume measuring unit for measuring the volume of the bladder according to the shape of the bladder. According to the shape feature-based ultrasonic image bladder volume measuring method and device, shape difference shown in different states by the bladder in clinical application is combined, the shape of the bladder is used as priori knowledge, the volume of the bladder is automatically calculated according to the current shape of the bladder, and the accuracy for measuring the volume of the bladder is improved.
Owner:深圳市大深生物医学工程转化研究院

Pessary device

A pessary having a main stem and an inflatable bladder disposed about the proximal larger diameter section of the main stem. The main stem further provides a distal smaller diameter portion having a cap at its distal tip and a check valve disposed there under. The check valve communicates with a central fluid passage that may extend into the proximal larger diameter section of the main stem. Secondary fluid passages connect the central fluid passage to the inflatable bladder volume disposed about the outer circumference of the proximal larger diameter section of the main stem. The main stem provides support to the pelvic structures and the inflatable bladder acts to hold the device in position. At least one void through the proximal larger diameter portion of the main stem allows bodily material to pass from the vagina through the pessary device thereby decreasing the amount of vaginal discharge.
Owner:ZIPPER RALPH

Method and system for calculating bladder volume

The invention discloses a method and system for calculating the bladder volume. The method includes the steps that bladder echo radio frequency data is obtained; an initial bladder contour line is obtained according to the amplitude difference of the bladder echo radio frequency data and the boundary continuity of the bladder; the initial bladder contour line is finely adjusted through a key point moving method, and a final bladder contour line is obtained; the bladder volume is calculated according to the final bladder contour line. The bladder contour is detected through original data, namely the bladder echo radio frequency data, limitation of the gray scale range and the influence of the boundary gray scale change are avoided, detection accuracy is improved, the bladder contour can be more accurately detected, and the precision of the calculated result of the bladder volume is improved. The contour line is better attached to an actual boundary by finely adjusting key points on the bladder contour line, the boundary can be accurately described, and then the more precise calculated result of the bladder volume is obtained. The method and system can be widely applied to the field of ultrasonic image processing.
Owner:SONOSCAPE MEDICAL CORP

Systems and methods for bladder health management

A system includes at least one wearable device configured to monitor a bladder volume of a user associated with the at least one wearable device, monitor moisture associated with the user, and transmit information regarding the bladder volume and moisture. The system also includes a display device configured to receive the information regarding the bladder volume and moisture from the at least one wearable device, and display information to the user based on the received information.
Owner:VERATHON

Bladder volume measurement and calculation method under abdominal two-dimensional ultrasound

The invention relates to a bladder volume measurement and calculation method under abdominal two-dimensional ultrasound. The method comprises the following steps that 1, the bladder is subjected to abdominal scanning, and a bladder two-dimensional image, namely, the median sagittal plane D1 is obtained through the ultrasound; 2, a probe is counterclockwise rotated by 90 degrees, and the maximum section, namely, the cross section D2 of the bladder median sagittal plane is obtained; 3, the probe is clockwise rotated by 45 degrees on the basis of the first median sagittal plane D1, and the maximum section, namely, the left slope D3 of the bladder median sagittal plane is obtained; 4, the probe is clockwise rotated by 45 degrees on the basis of the D2, and the maximum section, namely, the right slope D4 of the bladder median sagittal plane is obtained; 5, the center point Q of the median sagittal plane is positioned; 6, the median sagittal plane D1, the left slope D3 and the right slope D4 are measured; 7, the cross section D2 is measured; 8, the actual volume of the bladder is calculated according to a formula.
Owner:CHINA THREE GORGES UNIV

Bladder monitoring

InactiveUS20200196979A1Reduce the amount requiredSignal processing typically is rather computationally intensiveImage analysisOrgan movement/changes detectionPelvic regionPhased array
The present application discloses a bladder monitoring system comprising a wearable bladder monitoring device (1) including securing means (27, 29) for securing the device to a subject's (40) body; a phased array (11) of ultrasound transducers (10); and a phased array controller (13) adapted to control the phased array to direct a plurality of ultrasound beams (30, 30′, 30″) into the subject's body under a range of beam angles, as well as a signal processor (23) adapted to receive data pertaining to echo signals (31, 31′, 31″) of said ultrasound beams from the phased array. The signal processor is adapted to process said data in order to identify an edge of the subject's pelvic bone (43) proximal to the subject's bladder (41) from data pertaining to at least one of said echo signals; determine an orientation of the wearable bladder monitoring device relative to the pelvic bone based on beam angle information associated with the at least one of said echo signals; and derive bladder information from the data based on the determined orientation. A method of obtaining bladder (volume) information with such a system is also disclosed.
Owner:KONINKLJIJKE PHILIPS NV

Wearable bladder urine volume ultrasonic monitoring system

The invention relates to a wearable bladder urine volume ultrasonic monitoring system, which comprises an ultrasonic detection unit, a host and a system terminal, the ultrasonic detection unit comprises a flexible stretchable wearable flexible substrate and a plurality of ultrasonic probes distributed on the flexible substrate, the host comprises a high-voltage excitation emitter, a T / R switch, a gating circuit controller, an AFE receiver, a data processor, a wireless transmission module and a power supply module, and the system terminal comprises a data receiving module, a data analysis module and a post-processing display module. On one hand, the bladder volume can be calculated without bladder imaging or reexamination, the defects that an existing single-array-element sensor is low in spatial resolution and poor in accuracy, needs professional auxiliary operation and the like can be overcome, the state of urine in the bladder can be conveniently obtained, and corresponding auxiliary information is provided for clinical monitoring and urination of a patient; and on the other hand, wearing is convenient, real-time measurement is facilitated, measurement time consumption is low, manufacturing cost is low, and the size is small.
Owner:SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI

Method and system for monitoring bladder capacity

The invention discloses a method and system for monitoring bladder capacity. The method includes: applying ultrasonic waves to the human body; receiving echo signals transmitted back from the walls of human body organs, and converting them into digital amplitude signals after processing; The signal is analyzed to obtain the information image, and the current bladder volume value is obtained according to the information image; it is determined that the current bladder volume value is greater than the bladder safety capacity value, and an alarm signal is issued. The present invention acts on the human body through ultrasonic waves, receives the echo signal reflected by the human body, analyzes and processes the echo signal to obtain an information image, and then analyzes the current bladder volume value from the information image, so that according to the current bladder volume value and The comparison of bladder safety capacity values ​​determines whether to send an alarm signal to the voiding disorder to remind the voiding disorder to urinate, to achieve an early warning effect, to ensure the safety of the patient, and to avoid complications such as bladder-ureteral reflux and hydronephrosis.
Owner:何晓庆

Device and method for monitoring bladder volume of a subject

The present invention provides a device and a method for monitoring the bladder volume of a subject. A device for monitoring the bladder volume of a subject comprises a sensor to be attached to a region on the exterior surface of the abdomen of the subject, the region corresponding to the bladder of the subject, the sensor being configured to obtain a sensor signal indicating the bladder volume of the subject; a controlling unit configured to generate a control action signal if it determines, based on the sensor signal, that the change of the bladder volume of the subject exceeds a predetermined amount; an ultrasound probe to be attached to the subject and configured to emit, in response to the control signal, an ultrasonic signal toward the bladder of the subject and receive echo signals from the bladder of the subject; a deriving unit configured to derive the bladder volume of the subject from the received echo signals. According to the device, long-time monitoring of the bladder volume of the subject may be achieved.
Owner:KONINKLJIJKE PHILIPS NV

Simulation and analysis device for physiological processes of urine storage and emiction of bladder

The invention provides a simulation and analysis device for physiological processes of urine storage and emiction of the bladder, comprising an artificial bladder, an artificial urethra, a pelvic cavity sink, an extrusion device, a pressure device, a perfusion device, a urine recovery device, a pressure measuring device and a flow metering device. The artificial bladder is used for simulating thefeature that the bladder changes volume along with the liquid capacity and realizing the function of urine storage; the artificial urethra used as a channel for discharging liquid in the bladder; thepelvic cavity sink is used as the environment for containing organs of the bladder, and the like; the extrusion device is used for simulating extrusion caused by the peripheral organs of the bladder to the bladder; the pressure device is used for simulating the shrinkage of detrusor of the bladder so as to realize the function of emiction of the bladder; the perfusion device is used for accurately measuring and displaying the liquid amount perfused to the bladder in real time; the urine recovery device is used as liquid reserve of liquid pumping of the perfusion device and for collecting the liquid discharged from the urethra so as to facilitate recycling; the pressure measuring device is used for measuring and displaying inner pressure of the bladder and the inner pressure of a pelvic cavity in real time; and the flow metering device is used for measuring and displaying the flow of the liquid passing through the urethra in real time. The invention can realize the physiological processes of urine storage and emiction of the artificial bladder, analyzes the physiological process by controlling and monitoring urine dynamical parameters of bladder volume.
Owner:BEIHANG UNIV

Daytime wetting treatment device

PendingCN110393551AEnuresis self-healingUrination self-healingOrgan movement/changes detectionGymnastic exercisingComputer moduleEngineering
The invention relates to a daytime wetting treatment device. The daytime wetting treatment device comprises a main body patch and a main machine; an ultrasonic probe is installed in the middle of theinner side surface of the main body patch, and an oval adhesive patch is arranged at the edge of the inner side surface of the main body patch; the main machine is installed on the outer side surfaceof the main body patch; a display screen is arranged in the front of the main machine, alarms are installed on the left side and the right side of the display screen, and five adjustment buttons are installed under the display screen; a charging socket is formed in the right side of the main machine; and the main machine is internally provided with an ultrasonic transmitting module, an ultrasonicreceiving module, a data processing module and a display alarm module. The daytime wetting treatment device has the advantages that a bladder volume value of patients or children before urination is detected by an ultrasonic probe, and the bladder volume value is input into the display alarm module, and when the bladder volume value is reached, alarming is carried out to urge urination; in clinical, the daytime wetting treatment device can be used for patients who resume urination training after operation; and the bladder volume value input for alarming can be flexibly adjusted to adapt to physiological and psychological changes for children with different ages.
Owner:SHANGHAI CHILDRENS MEDICAL CENT AFFILIATED TO SHANGHAI JIAOTONG UNIV SCHOOL OF MEDICINE
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