The application relates to the technical field of
biomedical engineering, and particularly discloses a portable
insulin administration device, which comprises a non-invasive blood
glucose detection module arranged from bottom to top and used for monitoring
human blood glucose concentration based on a counter-
ion electro-
osmosis technology; a
drug loading module used for loading drugs, wherein the drugs comprise
insulin; and a transdermal administration module connected with the
drug loading module and used for applying a
pulse voltage to
skin to enhance the
transdermal penetration efficiency of the
skin and drive the drugs in the
drug loading module to penetrate into a
dermis layer when the monitored blood glucose concentration value is greater than a preset threshold value. The device adopts the counter-
ion electro-
osmosis technology to monitor the
human blood glucose concentration in real time, and realizes transdermal delivery of
insulin through the
electroporation technology, so that the two functions of blood glucose concentration monitoring and
insulin delivery are combined, the integration of symptom diagnosis and treatment is realized, and both functions can be realized in a completely non-invasive manner without causing damage to the
skin of a patient.